VISIONalso see GLAUCOMA

 

CONJUGATE DEVIATION OF THE EYES AFTER Cannabis indica INTOXICATION*         (full – 1964)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=505931&tool=pmcentrez

 

Delta 9-tetrahydrocannabinol: elevation of absolute visual thresholds of rabbits. (abst – 1979)                                         http://www.ncbi.nlm.nih.gov/pubmed/482306

 

Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications.        (abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=88

 

Ocular Effects of Topical Administration of {Delta}9-Tetrahydrocannabinol in Man (full – 1982)

http://archopht.ama-  assn.org/cgi/reprint/100/2/265?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searc hid=1&FIRSTINDEX=2960&resourcetype=HWCIT

 

Mydriasis induced by tetrahydrocannabinol (THC) in rats                      (full – 1982)  http://www.iovs.org/cgi/reprint/22/3/408?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuan a&searchid=1&FIRSTINDEX=640&resourcetype=HWCIT

 

Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9- tetrahydrocannabinol or cannabichromene.                                                               (abst – 1984)  http://www.ncbi.nlm.nih.gov/pubmed/6323206

 

Ocular hypotension, ocular toxicity, and neurotoxicity in response to marihuana extract and cannabidiol.                                               (abst – 1984)        http://www.ncbi.nlm.nih.gov/pubmed/6098513

 

Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol.                                               (abst – 1984)       http://www.ncbi.nlm.nih.gov/pubmed/6499952

 

Persistent visual changes following hashish consumption.                     (full – 1993)

 

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC513962/?page=1

 

HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy.                                                        (abst – 1996)      http://www.ncbi.nlm.nih.gov/pubmed/8714863

 

Patent 5631297 – Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same

(full – 1997)              http://www.patentstorm.us/patents/5631297/fulltext.html

 

Smoking dope restored my sight                 (news/anecdotal – 1998)

http://news.bbc.co.uk/2/hi/health/212301.stm

 

Effects of synthetic delta9-tetrahydrocannabinol on binocular depth inversion of natural and artificial objects in man.                                                  (abst – 1999)    http://www.ncbi.nlm.nih.gov/pubmed/10208314

 

Links found between marijuana and vision                (news – 1999)

http://archives.cnn.com/1999/HEALTH/12/07/science.marijuana/index.html

 

Cannabinoids’ Role In Retinal Function Described                (news – 1999)

http://www.sciencedaily.com/releases/1999/12/991208061213.htm

 

Different effects of nabilone and cannabidiol on binocular depth inversion in Man. (abst – 2000)                                    http://www.ncbi.nlm.nih.gov/pubmed/10837858

 

Neuroprotective Effect of(−)Δ9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-d- Aspartate-Induced Retinal Neurotoxicity – Involvement of Peroxynitrite                                                            (full – 2003)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892413/?tool=pmcentrez

 

Dexanabinol (HU-211) has a beneficial effect on axonal sprouting and survival after rat optic nerve crush injury.                                                     (abst – 2003)         http://www.ncbi.nlm.nih.gov/pubmed/12535983

 

Cannabis improves night vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif mountains of northern Morocco                                                                         (full – 2004)  http://science.iowamedicalmarijuana.org/pdfs/misc/Russo%20et%20al.%20Cannabis%20Night%20Vision

%20JEP%202004.pdf

 

Cannabidiol Preserves Retinal Neurons and Reduces Vascular Permeability in Experimental Diabetes     (abst – 2004)  http://abstracts.iovs.org/cgi/content/abstract/45/5/860?maxtoshow=&hits=80&RESULTFORMAT=&fullte  xt=cannabinoid&searchid=1&FIRSTINDEX=1760&resourcetype=HWCIT

 

When spliff gets in your eyes…             (news – 2004)

http://www.guardian.co.uk/science/2004/jul/07/sciencenews.research

 

In-vitro corneal permeation of cannabinoids and their water-soluble phosphate ester prodrugs.     (abst – 2005)                             http://www.ncbi.nlm.nih.gov/pubmed/16105235

 

Marijuna Cured My Color-Blindness               (anecdotal – 2005

http://mmj.tribe.net/thread/ae2e9a56-f117-4e96-b24d-ae799e956b00

 

Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes (full – 2006)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592672/?tool=pubmed

 

R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase- 2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells.

(full – 2006)               http://jpet.aspetjournals.org/content/316/3/1219.long

 

Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration.                                                       (abst – 2006)  http://www.ncbi.nlm.nih.gov/pubmed/17011761

 

Marijuana Compound May Help Stop Diabetic Retinopathy              (news – 2006)

http://www.sciencedaily.com/releases/2006/02/060227184647.htm

 

Getting Eye On Cannabinoids              (news – 2006)

http://www.thehempire.com/index.php/cannabis/news/getting_eye_on_cannabinoids

 

Marijuana compound could prevent eye damage in diabetics               (news – 2006)  http://www.thehempire.com/index.php/cannabis/news/marijuana_compound_could_prevent_eye_damage_i   n_diabetics

 

Endocannabinoids in the retina: From marijuana to neuroprotection.  (full – 2008)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584875/?tool=pmcentrez

 

Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation.        (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592995/?tool=pubmed

 

Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action.                                                     (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637200/?tool=pubmed

 

Mediation of Cannabidiol anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor                                                (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2588644/?tool=pmcentrez

 

Reduction of Congenital Nystagmus in a Patient after Smoking Cannabis. (abst – 2008)  http://www.unboundmedicine.com/medline/ebm/record/18306120/abstract/Reduction_of_Congenital_N yst  agmus_in_a_Patient_after_Smoking_Cannabis_

 

Assessing changes in pupillary size in Rifian smokers of kif (Cannabis sativa L.). (abst – 2008)                                  http://www.ncbi.nlm.nih.gov/pubmed/18511011

 

The role of endocannabinoid system in physiological and pathological processes in the eye           (abst – 2008)

 

http://www.unboundmedicine.com/medline/ebm/record/19195174/abstract/%5BThe_role_of_endocannabi noid_system_in_physiological_and_pathological_processes_in_the_eye%5D

 

Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development. (full – 2009)    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955420/?tool=pubmed

 

Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells.           (full – 2009)                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697670/?tool=pubmed

 

Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes.        (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925907/?tool=pubmed

 

Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation. (full– 2010)                                    http://www.wjgnet.com/1948-9358/full/v1/i1/12.htm

 

Cannabinoid (JWH-133) therapy could be effective for treatment of corneal neovascularization   (link to PDF – 2010)  http://www.doaj.org/doaj?func=abstract&id=844832&q1=cannabinoid&f1=all&b1=or&q2=cannabis&f2=a ll&recNo=68&uiLanguage=en

 

Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells.         (abst – 2010)                                      http://www.ncbi.nlm.nih.gov/pubmed/20619260

 

Cannabinoid (JWH-133) therapy could be effective for treatment of corneal neovascularization   (abst – 2010)  http://www.doaj.org/doaj?func=abstract&id=844832&q1=Cannabinoid%20%28JWH-  133%29%20therapy%20could%20be%20effective%20for%20treatment%20of%20corneal%20neovascular ization%20&f1=all&b1=and&q2=&f2=all&recNo=1&uiLanguage=en

 

Are There Any Herbal Supplements to Reduce Intraocular Pressure?               (news – 2010)  http://www.livestrong.com/article/337990-are-there-any-herbal-supplements-to-reduce-intraocular-  pressure/#ixzz21Iz6sfdN

 

Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study.                                                                   (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096803/

 

Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism.                                              (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933347/?tool=pubmed

 

2-Arachidonoylglycerol (2-AG) Induces Corneal Epithelial Cell Migration via Cannabinoid CB1 Receptors                                                            (abst – 2011)  http://abstracts.iovs.org/cgi/content/abstract/52/6/1995?maxtoshow=&hits=80&RESULTFORMAT=&fullt  ext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT

 

Endocannabinoid CB1 receptors modulate visual output from the thalamus. (abst – 2011)                                        http://www.ncbi.nlm.nih.gov/pubmed/21773721

 

Comparison Of Rat And Human Eyes For The Presence And Distribution Of Cb1 And Cb2 Receptors   (abst – 2011)  http://abstracts.iovs.org/cgi/content/abstract/52/6/4588?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT

 

Enhanced solubility, stability, and transcorneal permeability of delta-8- tetrahydrocannabinol in the presence of cyclodextrins.

(abst – 2011)                http://www.ncbi.nlm.nih.gov/pubmed/21637944

 

Indirect Sympatholytic Actions at β-Adrenoceptors Account for the Ocular Hypotensive Actions of Cannabinoid Receptor Agonists                                                         (abst – 2011)  http://jpet.aspetjournals.org/content/339/3/757.abstract?sid=2ef42c80-59ad-4b4e-8eed-d5b9d556b866

 

Nonpsychotropic Cannabinoids, Abnormal Cannabidiol and Canabigerol-Dimethyl Heptyl, Act at Novel Cannabinoid Receptors to Reduce Intraocular Pressure.

(abst – 2011)               http://www.ncbi.nlm.nih.gov/pubmed/21770780

 

Expression and localization of the cannabinoid receptor type 1 and the enzyme fatty acid amide hydrolase in the retina of vervet monkeys.                                                    (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22142900

 

Effects of Palmitoylethanolamide on Aqueous Humor Outflow.             (abst – 2012)

http://www.ncbi.nlm.nih.gov/pubmed/22589443

 

Effect of ion pairing on in vitro transcorneal permeability of a Δ(9) -tetrahydrocannabinol prodrug: potential in glaucoma therapy.                                                (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/21989812

 

Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammation.                                                                 (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22807196

 

Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23142606?dopt=Abstract

 

Involvement of a non-CB1/CB2 cannabinoid receptor in the aqueous humor outflow- enhancing effects of abnormal-cannabidiol.                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22580290

 

Developmental and Visual Input-Dependent Regulation of the CB1 Cannabinoid Receptor in the Mouse Visual Cortex.                                                               (full – 2013)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540079/

 

Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle                                                    (abst – 2013)

http://www.ncbi.nlm.nih.gov/pubmed/23396229

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