THC ACID/ THCA – non-psychoactive precursor of THC

 

The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Delta1-tetrahydrocannabinolic acid synthase from Cannabis sativa L. (full – 2004)                                           http://www.jbc.org/content/279/38/39767.long

 

Crystallization of Δ1-tetrahydrocannabinolic acid (THCA) synthase from Cannabis sativa (full – 2005)                                         http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1952348&tool=pmcentrez

 

Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways.            (abst – 2006)                                         http://www.ncbi.nlm.nih.gov/pubmed/16504929

 

THC inhibits primary marker of Alzheimer’s disease                         (news – 2006)

http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=225#3

 

Identification and Characterization of Cannabinoids That Induce Cell Death through Mitochondrial Permeability Transition in Cannabis Leaf Cells                                                                      (full – 2007)  http://www.jbc.org/content/282/28/20739.full?sid=a5db98db-ff96-4187-8790-57097bbe15c1

 

Production of THC acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris.      (abst – 2007)                                http://marijuana.researchtoday.net/archive/4/8/1331.htm

 

Cannabinoids act as necrosis-inducing factors in Cannabis sativa                      (full – 2008)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2634471&tool=pmcentrez

 

Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception     (full – 2009)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765124/?tool=pubmed

 

Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full – 2011)  https://www.jstage.jst.go.jp/article/bpb/34/5/34_5_774/_pdf

 

Cannabis as a Unique Functional Food                     (full – 2011)

http://www.cannabisinternational.org/info/treatingyourself.pdf

 

Immunochemical approach using monoclonal antibody against Δ(9)- tetrahydrocannabinolic acid (THCA) to discern cannabis plants and to investigate new drug candidates.     (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21143135/abstract/Immunochemical_approach_usi

 

 

bis_plants_and_to_investigate_new_drug_candidates_

 

A real-time PCR assay for the relative quantification of the tetrahydrocannabinolic acid (THCA) synthase gene in herbal Cannabis samples                                                                   (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/22093702/abstract/A_real_time_PCR_assay_for_t

 

 

 

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.                                                        (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_

 

Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects.                                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22411724

 

Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP(+) affected murine mesencephalic cultures.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22571976

 

Structure and Function of Δ1-Tetrahydrocannabinolic Acid (THCA) Synthase, the EnzymeControlling the Psychoactivity of Cannabis sativa.                                                            (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22766313

 

Differential Modulation by Delta(9)-Tetrahydrocannabinol (∆ (9)-THC) of CD40 Ligand (CD40L) Expression in Activated Mouse Splenic CD4(+) T cells.                                                            (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22851303

 

Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR.                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23280038

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