SPINAL CORD INJURY

 

The perceived effects of marijuana on spinal cord injured males.                     (abst – 1974)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=138

 

Marihuana as a therapeutic agent for muscle spasm or spasticity.                    (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=53

 

Cannabis effect on spasticity in spinal cord injury.                     (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=113

 

The effect of delta-9-THC on human spasticity.                      (abst – 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=154

 

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. (abst – 1990)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=160

 

Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivative.  (abst – 1995)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=112

 

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients.                                                (abst – 1996)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=12

 

Involvement of Dynorphin B in the Antinociceptive Effects of the Cannabinoid CP55,940 in the Spinal Cord    (full – 1997)                                  http://jpet.aspetjournals.org/content/281/2/730.full

 

Cannabis and cannabinoids: pharmacology and rationale for clinical use                (abst – 1999)

http://www.ncbi.nlm.nih.gov/pubmed/10575283

 

Selective cannabinoid CB1 receptor activation inhibits spinal nociceptive transmission in vivo.    (full – 2001)                     http://jn.physiology.org/content/86/6/3061.long

 

Clinical investigation of delta-9-tetrahydrocannabinol (THC) as an alternative therapy for overactive bladders in spinal cord injury (SCI) patients.                                                    (abst – 2001)  http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=102

 

The treatment of spasticity with D9-tetrahydrocannabinol (D9-THC) in patients with spinal cord injury  (abst – 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=79

 

Therapeutic potential of cannabinoids in CNS disease.                 (abst – 2003)

http://www.ncbi.nlm.nih.gov/pubmed/12617697

 

Are oral cannabinoids safe and effective in refractory neuropathic pain?             (abst – 2004)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=143

 

Interaction between gamma-aminobutyric acid GABAB and cannabinoid CB1 receptors in spinal pain pathways in rat                                                             (abst – 2005)  http://www.sciencedirect.com/science/article/pii/S0014299905003870

 

Treatments for Chronic Pain in Persons With Spinal Cord Injury: A Survey Study (full – 2006)                                   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864800/?tool=pmcentrez

 

Antinociceptive effect of cannabinoid agonist WIN 55,212–2 in rats with a spinal cord injury     (full – 2006)                        http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez

 

Effects of a Cannabinoid Agonist on Spinal Nociceptive Neurons in a Rodent Model of Neuropathic Pain         (full – 2006)                              http://jn.physiology.org/cgi/content/full/96/6/2984

 

Cannabinoids In Medicine: A Review Of Their Therapeutic Potential                  (full – 2006)

http://www.doctordeluca.com/Library/WOD/WPS3-MedMj/CannabinoidsMedMetaAnalysis06.pdf

 

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.           (abst – 2006)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=166

 

Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury.    (full – 2008)                                     http://jpet.aspetjournals.org/content/326/1/12.long

 

Sustained antinociceptive effect of cannabinoid receptor agonist WIN 55,212-2 over time in rat model of neuropathic spinal cord injury pain                                         (full – 2009)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743245/?tool=pmcentrez

 

The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function                                                         (full – 2009)  http://content.karger.com/produktedb/produkte.asp?DOI=000201556&typ=pdf

 

Medical Marijuana and Whiplash               (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/97?ailment=whiplash-

 

Cannabinoid receptor-mediated antinociception with acetaminophen drug combinations in rats with neuropathic spinal cord injury pain.                                                      (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826109/?tool=pubmed

 

Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study. (abst – 2010)                                        http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=313

 

Cannabinoid subtype-2 receptors modulate the antihyperalgesic effect of WIN 55,212-2 in rats with neuropathic spinal cord injury pain.                                                      (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/20920894

 

The endocannabinoid 2-arachidonoylglycerol reduces lesion expansion and white matter damage after spinal cord injury.                                                        (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/20156559

 

A randomized, double-blinded, crossover pilot study assessing the effect of nabilone on spasticity in persons with spinal cord injury.                                                        (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/20434606

 

Cannabinoid Agonists Inhibit Neuropathic Pain Induced by Brachial Plexus Avulsion in Mice by Affecting Glial Cells and MAP Kinases.                                                      (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172222/?tool=pubmed

 

Modulation of inflammatory responses by a cannabinoid-2-selective agonist after spinal cord injury.       (full – 2011)                         http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235339/

 

Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury.                                                         (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21354467

 

Targetting CB1 Cannabinoid Receptor for Neuroprotetion in Spinal Cord Injury (abst – 2011)

 

http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/lb422?maxtoshow=&hits=80&   RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype

=HWCIT

 

Spinal Cord Injuries Induce Changes of CB1 Cannabinoid Receptor and C-C Chemokine Expression in Brain Areas Underlying Circuitry of Chronic Pain Conditions.

(abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21265596/abstract/Spinal_Cord_Injuries_Induce_   Changes_of_CB1_Cannabinoid_Receptor_and_C_C_Chemokine_Expression_in_Brain_Areas_Underlying

_Circuitry_of_Chronic_Pain_Conditions_

 

Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain.                                                             (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21813113

 

Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury.     (abst – 2011)                               http://www.ncbi.nlm.nih.gov/pubmed/21915768

 

Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury.                                                               (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/22210507

 

Early Endogenous Activation of CB1 and CB2 Receptors after Spinal Cord Injury Is a Protective Response Involved in Spontaneous Recovery                                                      (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496738/

 

A Role for the Cannabinoid 1 Receptor in Neuronal Differentiation of Adult Spinal Cord Progenitors in vitro is Revealed through Pharmacological Inhibition and Genetic Deletion.          (full – 2012)                                    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265030/?tool=pubmed

 

A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord   (full – 2012)  http://onlinelibrary.wiley.com/doi/10.1002/cne.23184/full

 

The interaction between intrathecal administration of low doses of  palmitoylethanolamide and AM251 in formalin-induced pain related behavior and spinal cord IL1-β expression in rats.      (abst – 2012)                                                                  http://www.ncbi.nlm.nih.gov/pubmed/22201038

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