SPASTICITY

 

The perceived effects of marijuana on spinal cord injured males.                      (abst – 1974)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=138

 

Marihuana as a therapeutic agent for muscle spasm or spasticity.                     (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=53

 

Treatment of human spasticity with delta 9-tetrahydrocannabinol.                    (abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=8

 

Cannabis effect on spasticity in spinal cord injury.                        (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=113

 

Effect of Delta-9-THC on EMG Measurements in Human Spasticity                    (abst – 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=110

 

The effect of delta-9-THC on human spasticity.                    (abst – 1986)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=154

 

Delta-9-THC in the treatment of spasticity associated with multiple sclerosis. (abst – 1987)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=1

 

Effect of cannabinoids on spasticity and ataxia in multiple sclerosis.                   (abst – 1989)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=2

 

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. (abst + 1st page – 1990)  http://www.springerlink.com/content/3826667673770p51/fulltext.pdf?page=1

 

Nabilone in the treatment of multiple sclerosis.               (abst – 1995)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=11

 

Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivative.  (abst – 1995)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=112

 

The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients.                                              (abst – 1996)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=12

 

Endocannabinoids control spasticity in a multiple sclerosis model              (full – 2000)  http://www.fasebj.org/cgi/reprint/00-  0399fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabis&andorexactfulltext=and&sear chid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=HWCIT

 

Cannabinoids in the treatment of pain and spasticity in multiple sclerosis.             (abst – 2002)  http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=12137404&dopt=abstrac tplus

 

Experiences with THC-treatment in children and adolescents             (abst – 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=80

 

The treatment of spasticity with D9-tetrahydrocannabinol (D9-THC) in patients with spinal cord injury  (abst – 2003)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=79

 

Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients.         (abst – 2004)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=56

 

Are oral cannabinoids safe and effective in refractory neuropathic pain?             (abst – 2004)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=143

 

Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy.Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study.            (abst – 2004)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=63

 

CB1 cannabinoid receptor-mediated modulation of food intake in mice             (full – 2005)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576140/?tool=pmcentrez

 

Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up.      (abst – 2005)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=160

 

Cannabis-based medicinal extract (Sativex) produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance.       (abst – 2005)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=170

 

The treatment of spasticity with Delta(9)-tetrahydrocannabinol in persons with spinal cord injury.           (abst – 2006)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=166

 

Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial.

(abst – 2006)  http://www.unboundmedicine.com/medline/ebm/record/16988792/abstract/Low_dose_treatment_with_the_ synthetic_cannabinoid_Nabilone_significantly_reduces_spasticity_related_pain_:_A_double_blind_placeb o_controlled_cross_over_trial_

 

Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis.                                                                      (abst – 2006)  http://www.ncbi.nlm.nih.gov/pubmed/17086911

 

Control of Spasticity in a Multiple Sclerosis Model is mediated by CB1, not CB2, Cannabinoid Receptors          (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189718/?tool=pmcentrez

 

Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis           (full – 2007)  http://medicalcannabis.com/images/pdf09/indications/ms/collin_et_al_2007_sativex.pdf

 

Motor effects of delta 9 THC in cerebellar Lurcher mutant mice.             (abst – 2007)

http://www.unboundmedicine.com/medline/ebm/record/17531329/abstract/Motor_effects_of_delta_9_THC

_in_cerebellar_Lurcher_mutant_mice

 

Cannabinoids in the management of spasticity associated with multiple sclerosis (full – 2008)                                   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626929/?tool=pmcentrez

 

Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review       (full – 2009)                                  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793241/

 

Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain                                                                         (full – 2009)  http://www.molecularpain.com/content/5/1/35

 

Marijuana Eases Spasticity in MS Patients                 (news – 2009)

http://www.webmd.com/multiple-sclerosis/news/20091204/marijuana-eases-spasticity-in-ms-patients

 

Medical Marijuana and Skeletal Muscular Spasticity                (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/120?ailment=skeletal-muscular-spasticity

 

Marijuana Chemicals Ease MS Symptoms, Review Confirms                (news – 2009)

http://www.drugfree.org/uncategorized/marijuana-chemicals-ease-ms

 

Cannabis can reduce spasticity in MS patients               (news – 2009)

http://www.news-medical.net/news/20091204/Cannabis-can-reduce-spasticity-in-MS-patients.aspx

 

Medical Marijuana and Spasticity                (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/119?ailment=spasticity

 

New approaches in the management of spasticity in multiple sclerosis patients: role of cannabinoids         (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835560/?tool=pmcentrez

 

Meta-analysis of the efficacy and safety of Sativex (nabiximols), on spasticity in people with multiple sclerosis                                                   (abst – 2010)  http://msj.sagepub.com/cgi/content/abstract/16/6/707?maxtoshow=&hits=80&RESULTFORMAT=&fullte  xt=cannabis&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HWCIT

 

Emerging treatment options for spasticity in multiple sclerosis; clinical utility of cannabinoids      (link to PDF – 2011)  http://www.doaj.org/doaj?func=abstract&id=842067&q1=cannabinoid&f1=all&b1=or&q2=cannabis&f2=a  ll&recNo=30&uiLanguage=en

 

A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex(®) ), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis.     (abst – 2011)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=322

 

THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis.                                                    (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21456949/abstract/THC_and_CBD_oromucosal_s

 

 

 

Cannabinoids in children                 (abst – 2011)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=295

 

Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial.          (full – 2012)                         http://www.cmaj.ca/content/184/10/1143.long

 

Clinical efficacy and effectiveness of Sativex, a combined cannabinoid medicine, in multiple sclerosis-related spasticity.                                                            (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22509985

 

Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis.     (abst – 2012)                             http://www.ncbi.nlm.nih.gov/pubmed/22954177

 

Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis.    (abst – 2012)  http://www.unboundmedicine.com/medline/ebm/record/22928118/abstract/Evaluation_of_the_Effects_of_

 

Sativex


THC_BDS:_CBD_BDS__on_Inhibition_of_Spasticity_in_a_Chronic_Relapsing_Experimental_

 

Allergic_Autoimmune_Encephalomyelitis:_A_Model_of_Multiple_Sclerosis_

 

Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity. (abst – 2012)                                          http://www.ncbi.nlm.nih.gov/pubmed/22973422

 

What place for cannabis extract in MS?                  (abst – 2012)

http://dtb.bmj.com/content/50/12/141.abstract

 

Treatment of spasticity in multiple sclerosis: new perspectives regarding the use of cannabinoids  (abst – 2012)                                             http://www.ncbi.nlm.nih.gov/pubmed/23011861

 

Cost Effectiveness of Oromucosal Cannabis-Based Medicine (Sativex®) for Spasticity in Multiple Sclerosis.                                                     (abst – 2012)       http://www.ncbi.nlm.nih.gov/pubmed/23072659

 

Treatment of spasticity in multiple sclerosis: new perspectives regarding the use of cannabinoids  (abst – 2012)                                         http://www.ncbi.nlm.nih.gov/pubmed/23011861?dopt=Abstract

 

Smoked Cannabis Reduces Some Symptoms of Multiple Sclerosis                    (news – 2012)  http://health.ucsd.edu/news/releases/Pages/2012-05-14-smoked-cannabis-reduces-symptoms-of-multiple-  sclerosis.aspx

 

Cannabis as Painkiller                         (news – 2012)

http://www.sciencedaily.com/releases/2012/08/120807101232.htm

 

Endocannabinoid system modulator use in everyday clinical practice in the UK and Spain.          (abst – 2013)                                http://www.ncbi.nlm.nih.gov/pubmed/23369054

 

A new multiple sclerosis spasticity treatment option: effect in everyday clinical practice and cost-effectiveness in Germany.                                                                (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23369055

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