Protection Against Septic Shock and Suppression of Tumor Necrosis Factor α and Nitric Oxide Production by Dexanabinol (HU-211), a Nonpsychotropic Cannabinoid

(full – 1997)           


Cardiovascular actions of cannabinoids and their generation during shock.                  (abst – 1998)


Endocannabinoid Degradation, Endotoxic Shock and Inflammation (link to PDF – 2002)                                            


Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats                                                                      (full – 2004)


Effects of AM281, a cannabinoid antagonist, on systemic haemodynamics, internal carotid artery blood flow and mortality in septic shock in rats                                                                       (full – 2005)


Effects of AM281, a cannabinoid antagonist, on circulatory deterioration and cytokine production in an endotoxin shock model: comparison with norepinephrine.

(abst – 2006)                 


The cannabinoid receptor 2 is critical for the host response to sepsis.                      (full – 2009)


Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full – 2010)                               









Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture.                                                      (abst – 2010)


Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study                                                     (full – 2011)


The endocannabinoid system in sepsis – a potential target to improve microcirculation? (full – 2011)  target-to-improve-microcirculation


Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis                                                            (full – 2012)


Cannabinoid receptor 1 inhibition causes seizures during anesthesia induction in experimental sepsis.       (abst – 2012)                                 


Inhibition of endocannabinoid degradation in experimental endotoxemia reduces leukocyte adhesion and improves capillary perfusion in the gut.                                                                               (abst – 2013)

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