Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy.      (full – 1975)                                 


Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate   (full – 1979)                       


Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo                                                                       (abst – 1979)









Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9- tetrahydrocannabinol.    (abst – 1979)


Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy.                                                    (abst – 1979)


Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo.                                                                       (abst – 1979)


Double-blind comparison of the antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis.                                                      (abst – 1980)


Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis                                            (abst – 1980)


The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy.                                                                              (abst – 1980)


Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine.                           (abst – 1980)


Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics.          (abst – 1981)


Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications.       (abst – 1981)


Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting.                                                                      (abst – 1981)


Comparative trial of the antiemetic effects of THC and haloperidol             (abst – 1981)


A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy.                                              (abst – 1982)









Cannabis and cancer chemotherapy: a comparison of oral delta-9-THC and prochlorperazine.       (abst – 1982)                                


A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting.                                                 (abst – 1982)


Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy.       (full -1983)


Levonantradol: a synthetic cannabinoid in the treatment of severe chemotherapy-induced nausea and vomiting resistant to conventional anti-emetic therapy.                                                 (abst – 1983)


THC or Compazine for the cancer chemotherapy patient–the UCLA study. Part II: Patient drug preference.                                                     (abst – 1985)


A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. (abst – 1985)


Antiemetic efficacy of levonantradol compared to delta-9-tetrahydrocannabinol for chemotherapy-induced nausea and vomiting.                                                                 (abst – 1985)


Nabilone and metoclopramide in the treatment of nausea and vomiting due to cisplatinum: a double blind study.                                                                    (abst – 1986)


Nabilone: an alternative antiemetic for cancer chemotherapy.                (abst – 1986)


Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy.                                                      (abst – 1986)


Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis.                                                                  (abst – 1986)


Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial.                                                      (abst – 1987)


A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea.                                                     (abst – 1987)







Oral vs. Inhaled Cannabinoids for Nausea/Vomiting from Cancer Chemotherapy (full – 1988)                          


Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst – 1988)                          


A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues.                                                                                            (abst – 1988)


Marijuana as antiemetic medicine: a survey of oncologists’ experiences and attitudes. (abst – 1991)                                   


Effect of nabilone on nausea and vomiting after total abdominal hysterectomy. (abst – 1994)


Effect of nabilone on nausea and vomiting              (letter – 1995)  acttitle=and&andorexacttitleabs=and&fulltext=cannabinoid&andorexactfulltext=and&searchid=1&FIRSTI NDEX=0&sortspec=relevance&resourcetype=HWCIT


An efficient new cannabinoid antiemetic in pediatric oncology.             (abst – 1995)


Patent 5605928 – Antiemetic compositions                (full – 1997)


Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol (dronabinol).                                                   (abst – 1997)


Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review            (full – 2001)


Therapeutic Aspects of Cannabis and Cannabinoids              (full – 2001)


Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A.                                                   (full – 2001)


The cannabinoid agonist WIN55,212-2 suppresses opioid-induced emesis in ferrets. (full – 2001),212_2_Su  ppresses.29.aspx










The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst – 2001)                          


The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2                                                     (abst – 2001)


Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac                                                           (abst – 2001)


Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat? (abst – 2002)                          


Delta9-tetrahydrocannabinol selectively acts on CB1 receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets.                                                                  (full – 2003)


Cannabinoids suppress synaptic input to neurones of the rat dorsal motor nucleus of the vagus nerve       (full – 2004)              


A comparative analysis of the potential of cannabinoids and ondansetron to suppress cisplatin-induced emesis in the Suncus murinus (house musk shrew).

(abst – 2004)      


US Patent Application 20050165088 – Compositions comprising cannabinoids for treatment of nausea, vomiting, emesis, motion sickness or like conditions

(full – 2005)      


Cannabinoids In Medicine: A Review Of Their Therapeutic Potential                  (full – 2006)


Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting.                                                                                                 (abst – 2006)


Prevention of nausea and vomiting following breast surgery.             (abst – 2006)


The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients  (abst – 2006)


Experience with the Synthetic Cannabinoid Nabilone in Chronic Noncancer Pain (abst – 2006)







Methods evaluating cannabinoid and endocannabinoid effects on gastrointestinal functions.         (abst – 2006)                     


Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases.       (abst – 2006)


US Patent Application 20070049645 – Anti-nausea and anti-vomiting activity of cannabidiol compounds           (full – 2007)


THC improves appetite and reverses weight loss in AIDS patients              (abst – 2007)


Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: beyond prevention of acute emesis.                                                        (abst – 2007)


Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting.                                            (abst – 2007)


Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.    (abst – 2007)            


Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew.                                                          (abst – 2007)   emetic_activity_of_structurally_diverse_cannabinoids_against_radiation_induced_emesis_in_the_least_shr  ew


Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret.                                                    (abst – 2007)


Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects      (abst – 2008)                 


Medical marijuana: a surprising solution to severe morning sickness                  (news – 2008)  sickness.htm


Medical Marijuana and Severe Nausea              (news – 2009)


Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting                                                                  (full – 2010)







Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting                                                                       (link to PDF– 2010)


The abuse potential of the synthetic cannabinoid nabilone.               (abst – 2010)


Regulation of nausea and vomiting by cannabinoids                (abst – 2010)  5381.2010.01176.x/abstract;jsessionid=56CED9CE51B025C161AA2E821BEC94ED.d01t01


Motion Sickness, Stress and the Endocannabinoid System                (abst – 2010)


Medical Marijuana: Can Pot Help Pregnant Women With Vomiting and Nausea? (article – 2011)  help-pregnant-women-with-vomiting-and-nausea/


Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst – 2011)                                 


Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A) Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus.     (abst – 2011)


Regulation of nausea and vomiting by cannabinoids.                (abst – 2011) miting_by_cannabinoids_


How Does Marijuana Help Cancer Patients?               (news – 2011)


The Positive Uses of Marijuana for Cancer Patients                (news – 2011)


Medical Marijuana: Clearing Away the Smoke               (full – 2012)


Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting. (abst – 2012)                          


Tumor necrosis factor activation of vagal afferent terminal calcium is blocked by cannabinoids.   (abst – 2012)                          










Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?                                                    (abst – 2012)


The therapeutic potential of cannabis and cannabinoids.                    (abst – 2012)


Effects of parabolic flight and spaceflight on the endocannabinoid system in humans. (abst – 2012)                                  


Effects of dronabinol on morphine-induced dopamine-related behavioral effects in animals          (abst – 2012)                      


The anti-nausea effects of CB(1) agonists are mediated by an action at the visceral insular cortex.            (abst – 2012)            


Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT(1A) receptor activation.                                                            (abst – 2012)


Cannabis as Painkiller                         (news – 2012)

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