JZL-184– blocks breakdown of 2-AG


Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects           (full – 2009)                                         http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605181/


Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat        (full – 2012)



Monoacylglycerol lipase is a new therapeutic target for Alzheimer’s disease (full – 2012)                                           http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513645/










Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects.

(abst – 2013)                      http://www.ncbi.nlm.nih.gov/pubmed/23412396

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