Cannabinoid receptor genes.                  (abst – 1996)


Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia.       (abst – 2000)                                 


Association of a CB1 cannabinoid receptor gene (CNR1) polymorphism with severe alcohol dependence.                                                      (abst – 2002)


Marijuana receptor gene abnormality in schizophrenia                        (news – 2002)


Human cannabinoid receptor 1: 5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse.                                                                 (full – 2004)


Association study of cannabinoid receptor gene (CNR1) alleles and anorexia nervosa: differences between restricting and binging/purging subtypes.                                                      (abst – 2004)


Depression in Parkinson’s disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1)                                                                              (full – 2005)


Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders.                                                                         (full – 2005)


Cannabinoid receptor type 2 gene is associated with human osteoporosis (full – 2005)  ulltext=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT


Moderation of the Effect of Adolescent-Onset Cannabis Use on Adult Psychosis by a Functional Polymorphism in the Catechol-O-Methyltransferase Gene: Longitudinal Evidence of a Gene X Environment Interaction   (full – 2006)


(AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population                                                            (abst – 2006)







Women with a variant of the CB2 gene have a three-fold higher risk of osteoporosis (news – 2006)


Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation (full – 2007)  xt=cannabinoid&searchid=1&FIRSTINDEX=1120&resourcetype=HWCIT


Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men.                                                           (full – 2007)


The fatty acid amide hydrolase C385A (P129T) missense variant in cannabis users: studies of drug use and dependence in Caucasians                                                     (abst – 2007)


No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents.                                                           (abst – 2007)


Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men                                                        (full – 2008)


Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa    (full – 2008)                       


Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation.           (full – 2008)                    


Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder         (full – 2008)


Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations                                                       (full – 2008)


The role of fatty acid hydrolase gene variants in inflammatory bowel disease. (full – 2009)                         


Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects.                                               (abst – 2009)


The use and misuse of alcohol and marijuana can be traced to a common set of genes









(news – 2009)      


Cannabis and smoking gene links to schizophrenia ‘unfounded’               (news – 2009)


A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia.                                                      (full – 2010)


A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain.                                                         (full – 2010)


The Cannabinoid 1 Receptor (CNR1) 1359 G/A Polymorphism Modulates Susceptibility to Ulcerative Colitis and the Phenotype in Crohn’s Disease                                                       (full – 2010)


Effects of a Commonly Occurring Genetic Polymorphism of Human CYP3A4 (I118V) on the Metabolism of Anandamide                                                     (full – 2010)


Endocannabinoids and Schizophrenia             (link to PDF – 2010)


G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population.                                                        (abst – 2010)


A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands.

(abst – 2010)      


Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism.                                              (full – 2011)


Differential signaling in human cannabinoid CB(1) receptors and their splice variants in autaptic hippocampal neurons                                                        (full – 2011)


Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise       (full – 2011)                   


The association of the rs1049353 polymorphism of the CNR1 gene with hypoadiponectinemia.    (full – 2011)









CNR2 functional variant (Q63R) influences childhood immune thrombocytopenic purpura.         (full – 2011)


Cannabis, COMT and psychotic experiences.              (full – 2011)


The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction

(link to PDF – 2011)     


Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia.                                                   (abst – 2011)


Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. (abst – 2011)




The genetic basis of the endocannabinoid system and drug addiction in humans (abst – 2011)                           


Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. (abst – 2011)                           


Association study of Cannabinoid receptor 1 (CNR1) gene in tardive dyskinesia (abst – 2011)                         


The genetics of eating disorders.              (abst – 2011)


Genetic association between bipolar disorder and 524A>C (Leu133Ile) polymorphism of CNR2 gene, encoding for CB2 cannabinoid receptor.                                                           (abst – 2011)


Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women.  (abst – 2011)


Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease.                                                           (abst – 2011)


Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?                                                    (abst – 2011)










Testing bidirectional effects between cannabis use and depressive symptoms: moderation by the serotonin transporter gene                                             (abst – 2011)


COMT; another “wrong” result for the reefer madness hype.               (news – 2011)


The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription

(full – 2012)     


Alelle specific differences in the activity of a novel cannabinoid receptor 1(CNR1) gene intronic enhancer in hypothalamus, dorsal root ganglia and hippocampus.                                               (full – 2012)


The Interplay between Parental Monitoring and the Dopamine D4 Receptor Gene in Adolescent Cannabis Use  (full – 2012)


Cannabinoid Receptor 1 (CNR1) 4895 C/T Genetic Polymorphism was Associated with Obesity in Japanese Men.                                                             (full – 2012)


A polymorphism in the gene of the endocannabinoid-degrading enzyme FAAH (FAAH C385A) is associated with emotional–motivational reactivity                                                         (full – 2012)


The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription (full – 2012)                            


Endocannabinoids in stressed humans                (link to PDF – 2012) cNo=2&uiLanguage=en


Cannabinoid-related Agents in the Treatment of Anxiety Disorders: Current Knowledge and Future Perspectives.                                                      (abst – 2012)


Cannabinoid Receptor Genotype Moderation of the Effects of Childhood Physical Abuse on Anhedonia and Depression.                                                 (abst – 2012)


Genetic Epidemiology and Pharmacogenetics in Irritable Bowel Syndrome. (abst – 2012)                               


The G1359A-CNR1 gene polymorphism is associated to glioma in Spanish patients (abst – 2012)                              









G1359A polymorphism in the cannabinoid receptor-1 gene is associated with the presence of coronary artery disease in patients with type 2 diabetes.                                                                        (abst – 2012)


Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets.                                                                   (abst – 2012)


Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic Fatty liver disease.                                                        (abst – 2012)


Investigation of endocannabinoid system genes suggests association between peroxisome proliferator activator receptor-α gene (PPARA) and schizophrenia.                                                 (abst – 2012)


Genetic variability in the endocannabinoid system and 12-week clinical response to citalopram treatment: the role of the CNR1, CNR2 and FAAH genes                                                                  (abst – 2012)  ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=H WCIT


Failure to extinguish fear and genetic variability in the human cannabinoid receptor 1. (abst – 2012)                            


Childhood Obesity and the Role of Dopamine D2 Receptor and Cannabinoid Receptor-1 Gene Polymorphisms.                                                   (abst – 2012)


A genetic perspective on the proposed inclusion of cannabis withdrawal in DSM-5. (abst – 2012)                          


Impact of reference gene selection for type 2 cannabinoid receptor gene expression studies in human spermatozoa                                                                  (abst – 2012)


The Cannabinoid Receptor type 2 Q63R variant increases the risk of celiac disease: Implication for a novel molecular biomarker and future therapeutic intervention. (abst – 2012)                             


Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake. (abst – 2012)                           


Contribution of genetic variants to pain susceptibility in Parkinson disease

(abst – 2012)       


Sensation-seeking genes and physical activity in youth                  (abst – 2012)









Smoking Cannabis Increases Risk of Depression in the Case of Genetic Vulnerability, Study Finds         (news – 2012)                    


Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations.                                                               (full – 2013)


Epigenetic mechanisms and endocannabinoid signalling                       (full – 2013)


Cannabinoid Receptor 1 Gene and Irritable Bowel Syndrome: Phenotype and Quantitative Traits.           (abst – 2013)                                  


Evidence for the involvement of cannabinoid receptors’ polymorphisms in the pathophysiology of human diseases.                                                                                 (abst – 2013)


Genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) and their influence on anthropometric parameters and metabolic parameters under a high monounsaturated vs. high polyunsaturated fat hypocaloric diets.                                                                                               (abst – 2013)


Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding.                                                                                                        (abst – 2013)


Cannabinoid CB2 receptor gene (CNR2) polymorphism is associated with chronic childhood immune thrombocytopenia in Egypt.                                                  (abst – 2013)


Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.                                                                          (abst – 2013)


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