GLAUCOMAalso see VISION

 

Marihuana smoking and intraocular pressure.                       (abst – 1971)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=47

 

Marihuana and the eye.                   (full – 1975)       http://www.iovs.org/cgi/reprint/14/4/261

 

Marijuana smoking and reduced pressure in human eyes: drug action or epiphenomenon? (full – 1975)  http://www.iovs.org/cgi/reprint/14/1/52?ijkey=80da88f4d9414647a92b76d12895d1108a725d85

 

Editorial: Cannabis and eye function.                    (full – 1976)     http://www.iovs.org/cgi/reprint/15/4/243

 

Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye.            (full – 1976)                       http://www.iovs.org/cgi/reprint/15/2/102

 

Marijuana and vision–after ten years’ use in Costa Rica.                    (full – 1977)

http://www.iovs.org/cgi/reprint/16/8/689

 

Effect of delta-9-tetrahydrocannabinol on intraocular pressure in humans.                   (abst – 1977)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=40

 

 

 

 

 

 

 

 

 

Effects of tetrahydrocannabinol on arterial and intraocular hypertension.            (abst – 1979)

http://www.ncbi.nlm.nih.gov/pubmed/468444

 

US Patent 4189491 – Tetrahydrocannabinol in a method of treating glaucoma (full – 1980)                                    http://www.patentstorm.us/patents/4189491.html

 

Effect of marihuana on intraocular and blood pressure in glaucoma                (full – 1980)

http://www.ukcia.org/research/EffectOnIntraocularAndBloodPressureInGlaucoma.php

 

Topical delta 9-tetrahydrocannabinol and aqueous dynamics in glaucoma              (abst – 1981)

http://www.ncbi.nlm.nih.gov/pubmed/6271841

 

Cannabinoids in glaucoma: a primary screening procedure.               (abst – 1981)

http://www.ncbi.nlm.nih.gov/pubmed/6271842

 

Isolation of ocular hypotensive agents from Cannabis sativa                 (abst – 1981)

http://jcp.sagepub.com/cgi/content/abstract/21/8_suppl/479S?maxtoshow=&hits=80&RESULTFORMAT       =

&fulltext=marihuana&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT

 

Glaucoma, hypertension, and marijuana.                (full -1982)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2552967/?tool=pmcentrez&page=1

 

Ocular Effects of Topical Administration of {Delta}9-Tetrahydrocannabinol in Man (full – 1982)

http://archopht.ama-  assn.org/cgi/reprint/100/2/265?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searc hid=1&FIRSTINDEX=2960&resourcetype=HWCIT

 

Intraocular pressure following systemic administration of cannabinoids.              (abst – 1982)

http://www.ncbi.nlm.nih.gov/pubmed/6295702

 

Multiple-Drop Study of Topically Applied 1% {Delta}9-Tetrahydrocannabinol in Human Eyes   (abst – 1983)

http://archopht.ama-  assn.org/cgi/reprint/101/4/591?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabis&searchid=  1&FIRSTINDEX=2800&resourcetype=HWCIT

 

Intraocular pressure, ocular toxicity and neurotoxicity after administration of delta 9- tetrahydrocannabinol or cannabichromene.                                                         (abst – 1984)  http://www.ncbi.nlm.nih.gov/pubmed/6323206

 

Ocular Hypotension, Ocular Toxicity, and Neurotoxicity in Response to Marihuana Extract and Cannabidiol.                                                       (abst – 1984)  http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=6098513&dopt=abstract plus

 

Central Nervous System and Peripheral Mechanisms in Ocular Hypotensive Effect of Cannabinoids       (full- 1987)

 

 

 

 

 

 

 

 

http://archopht.ama-  assn.org/cgi/reprint/105/2/245?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searc  hid=1&FIRSTINDEX=720&resourcetype=HWCIT

 

A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol.            (abst – 1990)                             http://www.ncbi.nlm.nih.gov/pubmed/1965836

 

Patent 5631297 – Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same

(full – 1997)                http://www.patentstorm.us/patents/5631297/fulltext.html

 

Marijuana Smoking vs Cannabinoids for Glaucoma Therapy                (full – 1998)

http://archopht.ama-assn.org/cgi/content/full/116/11/1433

 

Smoking dope restored my sight                 (news/anecdotal – 1998)

http://news.bbc.co.uk/2/hi/health/212301.stm

 

Cannabis and cannabinoids: pharmacology and rationale for clinical use                (abst – 1999)

http://www.ncbi.nlm.nih.gov/pubmed/10575283

 

Involvement of Cannabinoid Receptors in the Intraocular Pressure-Lowering Effects of WIN55212-2    (full – 2000)                            http://jpet.aspetjournals.org/content/292/1/136.long

 

Therapeutic aspects of cannabis and cannabinoids.                (full – 2001)

http://bjp.rcpsych.org/cgi/content/full/178/2/107

 

Chronic Cannabis Use in the Compassionate Investigational New Drug Program: An Examination of Benefits and Adverse Effects of Legal Clinical Cannabis (full – 2002)    http://proxy.baremetal.com/cannabiscoalition.ca/chronic.pdf

 

Delta-9-tetrahydrocannabinol (THC) in the treatment of end-stage open-angle glaucoma. (full – 2002)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1358964/pdf/12545695.pdf/?tool=pmcentrez

 

Comparison of the enzymatic stability and intraocular pressure effects of 2- arachidonylglycerol and noladin ether, a novel putative endocannabinoid.                                                                              (full – 2002)  http://www.iovs.org/content/43/10/3216.full

 

Effect of WIN 55212-2, a Cannabinoid Receptor Agonist, on Aqueous Humor Dynamics in Monkeys    (full – 2003)

http://archopht.ama-  assn.org/cgi/content/full/121/1/87?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=marihuana&sear   chid=1&FIRSTINDEX=640&resourcetype=HWCIT

 

Cannabinoids and glaucoma                  (full – 2004)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1772142/?tool=pmcentrez

 

 

 

 

 

 

 

 

CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility.                                                                   (full – 2005)  http://www.iovs.org/content/46/6/1988.long

 

Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst – 2005)                                     http://www.ncbi.nlm.nih.gov/pubmed/15823551

 

Noladin ether acts on trabecular meshwork cannabinoid (CB1) receptors to enhance aqueous humor outflow facility.                                                    (full – 2006)      http://www.iovs.org/content/47/5/1999.long

 

R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase- 2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells.

(full – 2006)               http://jpet.aspetjournals.org/content/316/3/1219.long

 

Cannabinoids In Medicine: A Review Of Their Therapeutic Potential                  (full – 2006)

http://www.doctordeluca.com/Library/WOD/WPS3-MedMj/CannabinoidsMedMetaAnalysis06.pdf

 

Effect of Sublingual Application of Cannabinoids on Intraocular Pressure           (abst – 2006)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=201

 

Involvement of the Endocannabinoid System in Retinal Damage after High Intraocular Pressure–Induced Ischemia in Rats                                                            (full – 2007)  http://www.iovs.org/cgi/content/full/48/7/2997?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=can  nabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT

 

Neuroprotective and Intraocular Pressure-Lowering Effects of (-)Delta- Tetrahydrocannabinol in a Rat Model of Glaucoma.                                                                                          (abst – 2007)  http://www.unboundmedicine.com/medline/ebm/record/17284931/abstract/Neuroprotective_and_Intraocul

 

 

 

Additive Effects of Timolol and Cannabinoids on Intraocular Pressure in a Rat Glaucoma Model            (abst – 2007)  http://abstracts.iovs.org/cgi/content/abstract/48/5/4807?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT

 

Dronabinol and retinal hemodynamics in humans.                (abst – 2007)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=202

 

N-arachidonylethanolamide-Induced Increase in Aqueous Humor Outflow Facility (full – 2008)                                   http://www.iovs.org/cgi/content/full/49/10/4528

 

Mediation of Cannabidiol Anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor                                                  (full – 2008)  http://www.iovs.org/content/49/12/5526.full

 

Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor-Mediated Mechanism of Action                                                                  (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637200/?tool=pmcentrez

 

 

 

 

 

 

 

 

 

The role of endocannabinoid system in physiological and pathological processes in the eye           (abst – 2008)  http://www.unboundmedicine.com/medline/ebm/record/19195174/abstract/%5BThe_role_of_endocannabi noid_system_in_physiological_and_pathological_processes_in_the_eye%5D

 

Medical Marijuana and Glaucoma                (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/31?ailment=glaucoma

 

Are There Any Herbal Supplements to Reduce Intraocular Pressure?               (news – 2010)  http://www.livestrong.com/article/337990-are-there-any-herbal-supplements-to-reduce-intraocular-  pressure/#ixzz21Iz6sfdN

 

Alternative therapy in glaucoma management: Is there any role?               (full – 2011)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038502/?tool=pubmed

 

Ocular Hypotensive Effect of Oral Palmitoyl-ethanolamide: A Clinical Trial (full – 2011)

http://www.iovs.org/content/52/9/6096.full?sid=b5ebf404-f190-49ee-9076-758ee6c9190d

 

Cannabinoid applications in glaucoma.              (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21414525/abstract/Cannabinoid_applications_in_g  laucoma_

 

A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits. (abst – 2011)                                       http://www.ncbi.nlm.nih.gov/pubmed/21848425

 

Effect of ion pairing on in vitro transcorneal permeability of a Δ(9) -tetrahydrocannabinol prodrug: Potential in glaucoma therapy.                                                 (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21989812/abstract/Effect_of_ion_pairing_on_in_vi

 

tro_transcorneal_permeability_of_a_%CE%94_9 a_therapy_


tetrahydrocannabinol_prodrug:_Potential_in_glaucom

 

 

Comparison Of Rat And Human Eyes For The Presence And Distribution Of Cb1 And Cb2 Receptors   (abst – 2011)  http://abstracts.iovs.org/cgi/content/abstract/52/6/4588?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT

 

Nonpsychotropic Cannabinoids, Abnormal Cannabidiol and Canabigerol-Dimethyl Heptyl, Act at Novel Cannabinoid Receptors to Reduce Intraocular Pressure.

(abst – 2011)                http://www.ncbi.nlm.nih.gov/pubmed/21770780

 

Indirect Sympatholytic Actions at β-Adrenoceptors Account for the Ocular Hypotensive Actions of Cannabinoid Receptor Agonists                                                      (abst – 2011)  http://jpet.aspetjournals.org/content/339/3/757.abstract?sid=2ef42c80-59ad-4b4e-8eed-d5b9d556b866

 

January is Glaucoma Awareness Month: Can Marijuana save eyesight? (news / anecdotal – 2011)

 

 

 

 

 

 

 

 

http://www.examiner.com/norml-in-madison/january-is-glaucoma-awareness-month-can-marijuana-save- eyesight

 

Medical Reasons for Marijuana                       (news – 2011)

http://www.livestrong.com/article/98476-medical-reasons-marijuana/

 

In decades-old program, Uncle Sam provides pot                        (news – 2011)  http://www.msnbc.msn.com/id/44697173/ns/us_news-life/t/decades-old-program-uncle-sam-provides- pot/#.T3KO0YGRZpk

 

Effect of ion pairing on in vitro transcorneal permeability of a Δ(9) -tetrahydrocannabinol prodrug: potential in glaucoma therapy.                                                        (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/21989812

 

Effects of Palmitoylethanolamide on Aqueous Humor Outflow.                    (abst – 2012)

http://www.ncbi.nlm.nih.gov/pubmed/22589443

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