CHEMOTHERAPY

 

Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy.      (abst – 1975)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=4

 

 

 

 

 

 

 

 

 

Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate   (full – 1979)                             http://www.ukcia.org/research/AntiemeticForMethotrexate.php

 

Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo.                                                                       (abst – 1979)  http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=5

 

Delta-9-tetrahydrocannabinol (THC) as an antiemetic in patients treated with cancer chemotherapy; a double-blind cross-over trial against placebo                                                                 (abst – 1979)  http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=27

 

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9- tetrahydrocannabinol.    (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=107

 

Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy.                                                 (abst – 1979)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=126

 

Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis.                                             (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=6

 

The antiemetic activity of tetrahydrocanabinol versus metoclopramide and thiethylperazine in patients undergoing cancer chemotherapy.                                                                              (abst – 1980)  http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=24

 

Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine.                         (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=3

 

Double-blind comparison of the antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis.                                                    (abst – 1980)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=131

 

Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications.       (abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=88

 

Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting.                                                                      (abst – 1981)  http://www.ncbi.nlm.nih.gov/pubmed/7298877

 

Dose vs response of tetrahydroannabinol (THC) vs prochlorperazine as chemotherapy antiemetics.          (abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=30

 

 

 

 

 

 

 

 

 

Comparative trial of the antiemetic effects of THC and haloperidol               (abst – 1981)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=64

 

Levonantradol, a new antiemetic with a high rate of side-effects for the prevention of nausea and vomiting in patients receiving cancer chemotherapy.                                                       (abst – 1982)  http://www.ncbi.nlm.nih.gov/pubmed/7139853

 

Cannabis and cancer chemotherapy: a comparison of oral delta-9-THC and prochlorperazine.       (abst – 1982)                                          http://www.ncbi.nlm.nih.gov/pubmed/6284334

 

A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy.                                             (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=146

 

A multi-institutional Phase III study of nabilone vs. placebo in chemotherapy-induced nausea and vomiting.                                                  (abst – 1982)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=156

 

Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy.       (full – 1983)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2011510/?tool=pmcentrez&page=1

 

Levonantradol: a synthetic cannabinoid in the treatment of severe chemotherapy-induced nausea and vomiting resistant to conventional anti-emetic therapy.                                              (abst – 1983)  http://www.ncbi.nlm.nih.gov/pubmed/6309451

 

Antiemetic efficacy of levonantradol compared to delta-9-tetrahydrocannabinol for chemotherapy-induced nausea and vomiting.                                                               (abst – 1985)  http://www.ncbi.nlm.nih.gov/pubmed/2981616

 

THC or Compazine for the cancer chemotherapy patient–the UCLA study. Part II: Patient drug preference.                                                      (abst – 1985)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=34

 

A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. (abst – 1985)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=128

 

Nabilone: an alternative antiemetic for cancer chemotherapy.              (full – 1986)

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1777777

 

Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy                                                       (abst – 1986)  http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=127

 

Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis.                                                                 (abst – 1986)

 

 

 

 

 

 

 

 

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=129

 

Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial.                                                       (abst – 1987)

http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=120

 

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy (abst – 1988)                                     http://www.cannabis-med.org/studies/ww_en_db_study_show.php?s_id=31

 

A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues.                                                                                           (abst – 1988)  http://www.ncbi.nlm.nih.gov/pubmed/2838294

 

Marijuana as antiemetic medicine : A Survey of Oncologists’ Experiences and Attitudes (full – 1991)                                    http://www.maps.org/docs/doblin-mt.html

 

Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy- induced nausea and vomiting.                                              (abst – 1991)     http://www.ncbi.nlm.nih.gov/pubmed/1652611

 

An efficient new cannabinoid antiemetic in pediatric oncology               (full – 1995)

http://www.druglibrary.org/olsen/hemp/iha/iha02210.html

 

Therapeutic Aspects of Cannabis and Cannabinoids             (full – 2001)

http://bjp.rcpsych.org/cgi/reprint/178/2/107.pdf

 

Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review            (full – 2001)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC34325/?tool=pubmed

 

The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection. (abst – 2001)                                      http://www.ncbi.nlm.nih.gov/pubmed/11854768?dopt=Abstract

 

Different views on the association between cannabinoids and cancer             (abst – 2006)  http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=16835997&dopt=abstrac  tplus

 

Dronabinol for supportive therapy in patients with malignant melanoma and liver metastases        (abst – 2006)                                http://lib.bioinfo.pl/pmid:16408219

 

2nd synthetic marijuana drug OK’d for chemo effects                (news – 2006)

http://www.usatoday.com/news/health/2006-05-16-marijuana-drug_x.htm

 

Cesamet, THC and chemotherapy              (news – 2006)

http://www.sciencebase.com/science-blog/cesamet-thc.html

 

 

 

 

 

 

 

 

Activation of cannabinoid CB1 and CB2 receptors suppresses neuropathic nociception evoked by the chemotherapeutic agent vincristine in rats.                                       (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190028/?tool=pubmed

 

Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: beyond prevention of acute emesis.                                                       (abst – 2007)  http://www.ncbi.nlm.nih.gov/pubmed/17566383

 

Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting.                                          (abst – 2007)  http://www.ncbi.nlm.nih.gov/pubmed/17355735?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pub med_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

 

Pot Compound May Offer “Non-Toxic” Alternative To Chemotherapy               (news – 2007)

http://www.norml.org/index.cfm?Group_ID=7433

 

Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against Doxorubicin- Induced Cardiotoxicity                                                    (full – 2008)        http://content.onlinejacc.org/cgi/content/full/50/6/528

 

Oral nabilone capsules in the treatment of chemotherapy-induced nausea and vomiting and pain. (abst – 2008)                           http://www.ncbi.nlm.nih.gov/pubmed/18095921

 

Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines.         (abst – 2009)                    http://www.ncbi.nlm.nih.gov/pubmed/19394652

 

Efficacy of Crude Marijuana and Synthetic Delta-9-Tetrahydrocannabinol as Treatment for Chemotherapy-Induced Nausea and Vomiting: A Systematic Literature Review. (abst – 2009)

http://www.unboundmedicine.com/medline/ebm/record/19596652/abstract/Efficacy_of_Crude_Marijuana_ and_Synthetic_Delta_9_Tetrahydrocannabinol_as_Treatment_for_Chemotherapy_Induced_Nausea_and_V omiting:_A_Systematic_Literature_Review_

 

Medical Marijuana and Chemotherapy            (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/20?ailment=chemotherapy

 

Medical Marijuana and Radiation Therapy            (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/56?ailment=radiation-therapy

 

Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy.  (full – 2010)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869084/?tool=pubmed

 

Mechanisms of Broad-Spectemetic Efficacy of Cannabinoids against Chemotherapy- Induced Acute and Delayed Vomiting                                                             (link to PDF– 2010)  http://www.mdpi.com/1424-  8247/3/9/2930

 

Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting                                                                  (full – 2010)  http://www.unboundmedicine.com/medline/ebm/record/21039759/abstract/Preliminary_efficacy_and_safet y_of_an_oromucosal_standardized_cannabis_extract_in_chemotherapy_induced_nausea_and_vomiting_

 

 

 

 

 

 

 

 

 

Regulation of nausea and vomiting by cannabinoids             (abst – 2010)  http://onlinelibrary.wiley.com/doi/10.1111/j.1476-  5381.2010.01176.x/abstract;jsessionid=56CED9CE51B025C161AA2E821BEC94ED.d01t01

 

Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death

(full – 2011)               http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682269/

 

Brief Report: Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice.                                               (full – 2011)

http://www.anesthesia-analgesia.org/content/113/4/947.long

 

Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting                                                                      (link to PDF – 2010)  http://www.mdpi.com/1424-8247/3/9/2930

 

Marijuana Extract Might Help Prevent Chemotherapy-Related Nerve Pain  (news – 2011)

http://www.newswise.com/articles/marijuana-extract-might-help-prevent-chemotherapy-related-nerve-pain

 

Cannabinoid ‘Completely’ Prevents Chemotherapy-Induced Neuropathy, Study Says (news – 2011)                                    http://www.norml.org/index.cfm?Group_ID=8710

 

Ingredient in cannabis restores taste for cancer patients               (news – 2011)

http://phys.org/news/2011-02-ingredient-cannabis-cancer-patients.html

 

Cannabidiol may help prevent paclitaxel-induced peripheral neuropathy             (news – 2011)  http://www.news-medical.net/news/20110926/Cannabidiol-may-help-prevent-paclitaxel-induced-  peripheral-neuropathy.aspx

 

Marijuana component could ease pain from chemotherapy drugs                (news – 2011)

http://medicalxpress.com/news/2011-10-marijuana-component-ease-pain-chemotherapy.html

 

Father: Medical marijuana eased pain of my cancer-battling son               (anecdotal – 2011)

http://www.komonews.com/news/local/120941429.html

 

Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. (full – 2012)                                        http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366638/

 

The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB2 receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy                                                                                         (full – 2012)  http://www.molecularpain.com/content/8/1/71

 

Therapeutic utility of palmitoylethanolamide in the treatment of neuropathic pain associated with various pathological conditions: a case series                                                   (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500919/

 

 

 

 

 

 

 

 

Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting. (abst – 2012)                                             http://www.ncbi.nlm.nih.gov/pubmed/22491047

 

Prevention of Paclitaxel-Induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System                                                                        (abst – 2012)

http://www.anesthesia- analgesia.org/content/114/5/1104.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext=cannabi  noid&searchid=1&FIRSTINDEX=130&sortspec=date&resourcetype=HWCIT

 

The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB2 receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy.                                                                                                 (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22998838

 

Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: Effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment.    (abst – 2012)                                                   http://www.ncbi.nlm.nih.gov/pubmed/23127915

 

Prevention of paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system.                                                                                    (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22392969

 

Reefer tokin’ seniors in South Florida see pain go up in smoke                           (news – 2012)

http://articles.sun-sentinel.com/2012-07-23/news/fl-toking-oldsters-20120723_1_reefer-pain-seniors

 

Cannabis as Painkiller                         (news – 2012)

http://www.sciencedaily.com/releases/2012/08/120807101232.htm

 

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