CBR– CB2 CANNABINOID RECEPTOR no “high”, activated by THC, Anandamide, 2 -AG


Cannabinoid Receptor Ligands                       (full – undated)










Cannabinoids enhance human B-cell growth at low nanomolar concentrations. (abst – 1995)                                      http://www.ncbi.nlm.nih.gov/pubmed/7544292


Cannabis and cannabinoids: pharmacology and rationale for clinical use. (abst – 1999)                                    http://www.ncbi.nlm.nih.gov/pubmed/10575283


2-Arachidonoylglycerol and the cannabinoid receptors.              (abst – 2000)



Immunomodulation by Cannabinoids is Absent in Mice Deficient for the Cannabinoid Cb(2) Receptor.  (abst – 2000)  http://www.sciencedirect.com/science/article/pii/S0014299900002119


Involvement of central and peripheral cannabinoid receptors in the regulation of heart resistance to arrhythmogenic effects of epinephrine.                                                                (abst – 2000)  http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=11182823&dopt=abstrac tplus


Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor1           (full – 2001)                       http://cancerres.aacrjournals.org/cgi/reprint/61/15/5784.pdf


Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide                                                      (full – 2002)



Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease            (full – 2002)  http://bloodjournal.hematologylibrary.org/cgi/content/full/100/2/627?ijkey=eb71d6d7a06f311440761cfac6   a7d081bcc2771d


CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? (abst – 2002)                                    http://www.ncbi.nlm.nih.gov/pubmed/12550743


Anandamide and R-(+)-methanandamide prevent development of ischemic and reperfusion arrhythmia in rats by stimulation of CB2-receptors                                                                      (abst – 2002)  http://www.ncbi.nlm.nih.gov/pubmed/12227101


Lymphoma may be slowed by cannabis               (news – 2002)



Differential Roles of CB1 and CB2 Cannabinoid Receptors in Mast Cells             (full – 2003)



Cannabinoid CB2 Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer’s Disease Brains (full – 2003)

http://www.jneurosci.org/content/23/35/11136.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=  cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT










Endocannabinoid signalling in the blood of patients with schizophrenia (full – 2003)                                                  http://www.lipidworld.com/content/2/1/5


Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS                                                       (full – 2003)  http://www.pnas.org/content/100/18/10529.full


Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2 Cannabinoid Receptors          (full – 2003)  http://journals.lww.com/anesthesiology/Fulltext/2003/10000/Inhibition_of_Inflammatory_Hyperalgesia_by



Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN                                                    (full – 2003)  http://www.jleukbio.org/cgi/content/full/75/3/453?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=  cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT


Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea- pigs by cannabinoid (CB2) receptor activation.                                                  (full – 2003)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574031/?tool=pubmed


Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats                                                                   (full – 2004)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575196/?tool=pmcentrez


Cannabinoids and intestinal motility: welcome to CB2 receptors                (full – 2004)



The Peripheral Cannabinoid Receptor CB2 and CD40 Are Novel Biological Markers That Predict Outcome in Diffuse Large B-Cell Lymphoma of Elderly Patients.

(abst – 2004)  http://abstracts.hematologylibrary.org/cgi/content/abstract/104/11/3256?maxtoshow=&hits=80&RESULTF   ORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=800&resourcetype=HWCIT


Cannabinoid receptor type 2 gene is associated with human osteoporosis              (full – 2005)  http://hmg.oxfordjournals.org/cgi/content/full/14/22/3389?maxtoshow=&hits=80&RESULTFORMAT=&f  ulltext=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT


Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders.                                                                  (full – 2005)  http://www.jleukbio.org/content/78/1/231.long


Evidence that the plant cannabinoid Δ9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist                                                       (full – 2005)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751228/?tool=pubmed


Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full – 2005)                                    http://www.springerlink.com/content/tq777102q4185073/fulltext.html










Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor- independent mechanism         (full – 2005)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576089/?tool=pmcentrez


CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility.                                                                   (full – 2005)  http://www.iovs.org/content/46/6/1988.long


Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice (full – 2005)                                     http://www.nature.com/nature/journal/v434/n7034/full/nature03389.html


Identification and functional characterization of brainstem cannabinoid CB2 receptors. (full- 2005) (requires free registration)                                                         http://www.sciencemag.org/content/310/5746/329.full


Chemical modification of the naphthoyl 3-position of JWH-015: In search of a fluorescent probe to the cannabinoid CB2 receptor                                                                       (abst – 2005)  http://www.sciencedirect.com/science/article/pii/S0960894X05006803


Marijuana May Grow Neurons in the Brain                 (news – 2005)



The Cannabinoid CB2 Receptor as a Target for Inflammation-Dependent Neurodegeneration      (full – 2006)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435344/?tool=pmcentrez


Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression                                                 (full – 2006)  http://molpharm.aspetjournals.org/content/70/3/897.long


Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation (full – 2006)  http://www.fasebj.org/cgi/content/full/20/13/2405?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=  cannabis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HW  CIT


In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor?          (full – 2006)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013801/?tool=pubmed


Peripheral cannabinoid receptor, CB2, regulates bone mass                 (full – 2006)



Signaling pathways involved in the cardioprotective effects of cannabinoids. (full – 2006)                                    https://www.jstage.jst.go.jp/article/jphs/102/2/102_2_155/_pdf


Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects.                                                        (full – 2006)  http://www.jbc.org/content/281/20/14192.long










Involvement of the Cannabinoid CB2 Receptor and Its Endogenous Ligand 2- Arachidonoylglycerol in Oxazolone-Induced Contact Dermatitis in Mice                                                                       (full – 2006)  http://www.jimmunol.org/content/177/12/8796.full


New Natural Noncannabinoid Ligands for Cannabinoid Type-2 (CB2) Receptors (abst – 2006)                                     http://informahealthcare.com/doi/abs/10.1080/10799890600942674


Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production                                                          (abst – 2006)  http://www.ingentaconnect.com/content/klu/mcbi/2006/00000283/F0020001/00002346


Evolutionary Origins of the Endocannabinoid System.             (abst – 2006)



Towards a therapeutic use of selective CB2 cannabinoid receptor ligands for atherosclerosis.        (abst – 2006)                                        http://www.ncbi.nlm.nih.gov/pubmed/19804131


Researchers from the Hebrew University Discover New Drug for Osteoporosis (news – 2006)

http://news.softpedia.com/news/Researchers-From-the-Hebrew-University-Discover-New-Drug-for- Osteoporosis-15808.shtml


Women with a variant of the CB2 gene have a three-fold higher risk of osteoporosis (news – 2006)  http://www.xagena.it/news/medicinenews_net_news/8f1bac3967e0ff70ebc09d8ca5e08633.html


Activation of CB2 receptor attenuates bone loss in osteoporosis                (news – 2006)



Cannabinoid CB1 and CB2 Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Plaque Cell Subtypes in Human Multiple Sclerosis                                                        (full – 2007)  http://www.jneurosci.org/cgi/content/full/27/9/2396?maxtoshow=&hits=10&RESULTFORMAT=&fulltext




CB2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies                                                                       (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219542/?tool=pmcentrez


Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision.                                                        (full – 2007)  http://journals.lww.com/anesthesiology/pages/articleviewer.aspx?year=2007&issue=04000&article=00021



Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation     (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219529/?tool=pmcentrez









Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury (full – 2007)                                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228252/?tool=pmcentrez


Virodhamine and CP55,940 modulate cAMP production and IL-8 release in human bronchial epithelial cells.     (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042924/?tool=pubmed


In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219539/?tool=pmcentrez


Cannabinoid CB2 receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637559/?tool=pmcentrez


The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset                                                    (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819701/?tool=pmcentrez


CB2 receptors in the brain: role in central immune function                 (full – 2007)



Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation     (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219529/?tool=pmcentrez


Potential role for CB2 selective ligands as immunosuppressive agents                (full – 2007)



Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain            (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219541/?tool=pmcentrez


Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro      (full – 2007)  http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2189767&tool=pmcentrez


CB2 cannabinoid receptors promote mouse neural stem cell proliferation.              (abst – 2007)



Cannabinoids for the treatment of inflammation.              (abst – 2007)  http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Retrieve&list_uids=17520866&dopt=abstrac  tplus


Cannabinoid CB2 receptor activation prevents bronchoconstriction and airway oedema in a model of gastro-oesophageal reflux                                              (abst – 2007)  http://www.ncbi.nlm.nih.gov/pubmed/17643417









The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors                                                   (abst – 2007)  http://www.sciencedirect.com/science/article/pii/S0014299907007935


Role of cannabinoid CB2 receptors in glucose homeostasis in rats              (abst – 2007)



The cannabinoid CB(2) receptor: a good friend in the gut.             (abst – 2007)



Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humans          (abst – 2007)                        http://www.ncbi.nlm.nih.gov/pubmed/17189959


Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors.                                        (abst – 2007)        http://www.ncbi.nlm.nih.gov/pubmed/17205329


CB2 receptors in reproduction                (full – 2008)



Cannabinoid CB2 receptors in human brain inflammation                 (full – 2008)



Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats (full – 2008)                                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592089/?tool=pmcentrez


Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor                                                       (full – 2008)  http://endo.endojournals.org/cgi/content/full/149/11/5619?maxtoshow=&hits=80&RESULTFORMAT=&f  ulltext=cannabinoid&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT


The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9- tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin                                                      (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/


The CB2 Cannabinoid Receptor Controls Myeloid Progenitor Trafficking INVOLVEMENT IN THE PATHOGENESIS OF AN ANIMAL MODEL OF

MULTIPLE SCLEROSIS               (full – 2008)          http://www.jbc.org/content/283/19/13320.long


Cannabinoid receptors and the regulation of bone mass              (full – 2008)



Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats

(full – 2008)                     http://jpet.aspetjournals.org/content/327/2/584.full#content-block


CB2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies                                                                    (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219542/










Pleiotropic effects of the CB2 cannabinoid receptor activation on human monocyte migration: implications for atherosclerosis and inflammatory diseases                                                            (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267750/?tool=pubmed


Crucial Role of CB2 Cannabinoid Receptor in the Regulation of Central Immune Responses during Neuropathic Pain                                                                   (full – 2008)  http://www.jneurosci.org/cgi/content/full/28/46/12125


Expression of the Endocannabinoid System in Human First Trimester Placenta and Its Role in Trophoblast Proliferation                                                       (full – 2008)  http://endo.endojournals.org/content/149/10/5052.full?sid=f5b14012-9fbe-4f10-890c-386313060cf8


The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor.                                                                 (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677557/


Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats                                         (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494728/?tool=pubmed


Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation.    (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219529/?tool=pubmed


Endocannabinoids and Liver Disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases                                                                (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2376822/?tool=pmcentrez


Regression of Fibrosis after Chronic Stimulation of Cannabinoid CB2 Receptor in Cirrhotic Rats            (full – 2008)  http://jpet.aspetjournals.org/content/324/2/475.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=  cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT#content-block


Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning          (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219536/?tool=pmcentrez


Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product.                                                     (full – 2008)  http://www.ncbi.nlm.nih.gov/pubmed/18806815


CB2 receptors as new therapeutic targets for liver diseases.                (full – 2008)



The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.                                                       (full – 2008)  http://www.jbc.org/content/283/19/13320.long









Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain.                                                   (full – 2008)        http://www.jneurosci.org/cgi/content/full/28/46/12125


Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages         (full – 2008)  http://cardiovascres.oxfordjournals.org/content/81/4/805.full?sid=7d2438c4-a727-410f-870d-  4a971695b4fb


Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling.                                                                      (full – 2008)  http://www.fasebj.org/content/22/10/3685.long


Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation.                                                               (full – 2008)  http://onlinelibrary.wiley.com/doi/10.1002/ijc.23584/full


MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models.         (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597252/


Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain                                           (abst – 2008)  http://www.sciencedirect.com/science/article/pii/S0014299908000630


Role of CB2 receptors in neuroprotective effects of cannabinoids.             (abst – 2008)



Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption.                                                   (abst – 2008)         http://www.ncbi.nlm.nih.gov/pubmed/18991890


Glial expression of cannabinoid CB(2) receptors and fatty acid amide hydrolase are beta amyloid-linked events in Down’s syndrome.                                                       (abst – 2008)  http://www.ncbi.nlm.nih.gov/pubmed/18068305


Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs.          (abst – 2008)                         http://www.ncbi.nlm.nih.gov/pubmed/18266975


New Cannabis-Like Drugs Could Block Pain Without Affecting Brain, Says Study (news – 2008)                                     http://www.sciencedaily.com/releases/2008/09/080912091728.htm


Cannabislike Drugs May Hold Key to Treating Pain While Bypassing the Brain (news – 2008)                                     http://jama.jamanetwork.com/article.aspx?articleid=182826


Salutary pizza spice                  (news – 2008)










Ulcerative Colitis Induces Changes on the Expression of the Endocannabinoid System in the Human Colonic Tissue                                                          (full – 2009)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731878/?tool=pmcentrez


Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke.            (full – 2009)                  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855650/?tool=pubmed


Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects       (full – 2009)



Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development   (full – 2009)                                   http://www.rbej.com/content/7/1/121


The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi’s sarcoma cells in vitro            (full – 2009)  http://science.iowamedicalmarijuana.org/pdfs/cancer/Luca%20et%20al%202009%2019539619.pdf


The cannabinoid receptor 2 is critical for the host response to sepsis.              (full – 2009)



CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages                                                 (full – 2009)  http://cardiovascres.oxfordjournals.org/content/84/3/378.full?sid=7d2438c4-a727-410f-870d-  4a971695b4fb


Endocannabinoid signalling as an anti-inflammatory therapeutic target in atherosclerosis: does it work?   (full – 2009)  http://cardiovascres.oxfordjournals.org/content/84/3/341.full?sid=7d2438c4-a727-410f-870d-  4a971695b4fb


Endocannabinoids and Their Receptors as Targets for Obesity Therapy (full – 2009)                                 http://endo.endojournals.org/cgi/content/full/150/6/2531#top


Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)- Methanandamide and JWH-015: Involvement of CB2                                                                   (full – 2009)  http://www.nature.com/bjc/journal/v101/n6/full/6605248a.html


Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis. (full – 2009)                                 http://onlinelibrary.wiley.com/doi/10.1002/ibd.20960/full


Endocannabinoid-mediated control of synaptic transmission.              (full – 2009)



Microglial CB2 cannabinoid receptors are neuroprotective in Huntington’s disease excitotoxicity (full – 2009)                                    http://brain.oxfordjournals.org/content/132/11/3152.long









Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington’s disease.                                                          (abst – 2009)  http://www.ncbi.nlm.nih.gov/pubmed/19115380


Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications.                                                        (abst – 2009)  http://www.ncbi.nlm.nih.gov/pubmed/19897083


Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission.                                              (abst – 2009)  http://www.ncbi.nlm.nih.gov/pubmed/20590564


Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder.          (abst – 2009)                 http://www.ncbi.nlm.nih.gov/pubmed/19237169


CXCR4-chemokine receptor and Cannabinoid Receptor 2 (CB2) heterodimerization suggests a mechanism for breast metastasis regulation                                                           (abst – 2009)  http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2009/2_Annual_Meeting/4280?maxtosh ow=&hits=10&RESULTFORMAT=&fulltext=cannabinoid&andorexactfulltext=and&searchid=1&FIRSTI  NDEX=0&sortspec=date&resourcetype=HWCIT


The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells.          (abst – 2009)                       http://www.ncbi.nlm.nih.gov/pubmed/19908944


The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages.                                               (abst – 2009)  http://www.ncbi.nlm.nih.gov/pubmed/19505450?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPa   nel.Pubmed_RVDocSum&ordinalpos=18


CB2 cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion          (abst – 2009)                                       http://www.ncbi.nlm.nih.gov/pubmed/19162037                                                  


CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury.                                                          (abst – 2009)        http://www.ncbi.nlm.nih.gov/pubmed/19332079


The role of CB2 cannabinoid receptor and Leptin in hepatic fibrosis via lymphocyte alterations and HSC phagocytosis                                                   (abst – 2009)  http://www.docstoc.com/docs/76792678/The-role-of-CB2-cannabinoid-receptor-and-Leptin-in-hepatic-


Cough sensors. III. Opioid and cannabinoid receptors on vagal sensory nerves. (abst – 2009)                                     http://www.ncbi.nlm.nih.gov/pubmed/18825336


Cannabis may apparently stop prostate cancer growth                  (news – 2009)



The cannabinoid system: cannabinoids and receptors                 (news – 2009)  http://www.examiner.com/health-science-in-vancouver/the-cannabinoid-system-cannabinoids-and-  receptors










CB2: a cannabinoid receptor with an identity crisis.                (full – 2010)



International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2                                                                   (full – 2010)  http://pharmrev.aspetjournals.org/content/62/4/588.full.pdf+html


Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain                                                       (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845559/?tool=pmcentrez


Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment.     (full – 2010)                                        http://www.fasebj.org/content/24/3/788.long


Patent 7741365 Peripheral cannabinoid receptor (CB2) selective ligands             (full – 2010)



Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy.  (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869084/?tool=pubmed


N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor (full – 2010)  http://www.biomedcentral.com/1471-2202/11/44


Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain.                                                          (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132591/?tool=pubmed


Cannabinoid inhibition of macrophage migration to the trans-activating (Tat) protein of HIV-1 is linked to the CB(2) cannabinoid receptor.                                                     (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846023/?tool=pubmed


The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970523/?tool=pubmed


Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full – 2010)                                       http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed


Cannabinoid (JWH-133) therapy could be effective for treatment of corneal neovascularization   (link to PDF – 2010)  http://www.doaj.org/doaj?func=abstract&id=844832&q1=cannabinoid&f1=all&b1=or&q2=cannabis&f2=a ll&recNo=68&uiLanguage=en


Brain CB2 Receptors: Implications for Neuropsychiatric Disorders









(link to PDF– 2010)              http://www.mdpi.com/1424-8247/3/8/2517


Endocannabinoids and Schizophrenia             (link to PDF – 2010)



Endocannabinoids and Human Sperm Cells              (link to PDF – 2010)



Consider the CB(2) Receptor              (article – 2010)



A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands.

(abst – 2010)                  http://www.ncbi.nlm.nih.gov/pubmed/19768813


Brain cannabinoid CB2 receptor in schizophrenia.               (abst – 2010)



The cannabinoid receptor type 2 is time-dependently expressed during skeletal muscle wound healing in rats                                                  (abst – 2010)          http://www.ncbi.nlm.nih.gov/sites/pubmed


Cannabinoid subtype-2 receptors modulate the antihyperalgesic effect of WIN 55,212-2 in rats with neuropathic spinal cord injury pain.                                                     (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/20920894


The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors  (abst – 2010)  http://www.nature.com/neuro/journal/v13/n8/full/nn.2601.html


Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/19931541


Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity.                                                              (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/19147270


Cannabinoid (JWH-133) therapy could be effective for treatment of corneal neovascularization   (abst – 2010)  http://www.doaj.org/doaj?func=abstract&id=844832&q1=Cannabinoid%20%28JWH-  133%29%20therapy%20could%20be%20effective%20for%20treatment%20of%20corneal%20neovascular ization%20&f1=all&b1=and&q2=&f2=all&recNo=1&uiLanguage=en


Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain.                                                            (abst – 2010)    http://www.ncbi.nlm.nih.gov/pubmed/20863899


Functionally selective cannabinoid receptor signalling: Therapeutic implications and opportunities  (abst – 2010)                                                         http://www.sciencedirect.com/science/article/pii/S0006295210001553










The development of cannabinoid CBII receptor agonists for the treatment of central neuropathies.          (abst – 2010)  http://www.unboundmedicine.com/medline/ebm/record/20236042/abstract/The_development_of_cannabin  oid_CBII_receptor_agonists_for_the_treatment_of_central_neuropathies_


Role of the endocannabinoid system in alcoholic liver disease.                (abst – 2010)



Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery                                                                             (abst – 2010)  http://www.unboundmedicine.com/medline/ebm/record/20718749/abstract/Interaction_between_anandami   de_and_sphingosine_1_phosphate_in_mediating_vasorelaxation_in_rat_coronary_artery_


Studies demonstrate analgesic properties of synthetic cannabinoid                (news – 2010)  http://www.news-medical.net/news/20100702/Studies-demonstrate-analgesic-properties-of-synthetic-  cannabinoid.aspx


Deletion of CB2 Cannabinoid Receptor Induces Schizophrenia-Related Behaviors in Mice          (full – 2011)                       http://www.nature.com/npp/journal/v36/n7/full/npp201134a.html


Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis                                                           (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025486/?tool=pubmed


Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice (full – 2011)                                      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082575/?tool=pubmed


Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice.                                                                     (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109635/?tool=pubmed


WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full – 2011)                                   http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html


Targeting the CB2 cannabinoid receptor in osteoporosis               (full – 2011)

http://www.expert- reviews.com/doi/full/10.1586/eem.11.2?prevSearch=Keyword%253A%2528%2522cannabinoid%2522%2  529&searchHistoryKey=


New blood brothers: the GPR55 and CB2 partnership               (full – 2011)



Functional selectivity in CB2 cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB2 ligands.                                                (full – 2011)  http://molpharm.aspetjournals.org/content/early/2011/11/07/mol.111.074013.long


The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids.









(full – 2011)                http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198780/?tool=pubmed


Cannabinoid CB2 Receptors Contribute to Upregulation of β-endorphin in Inflamed Skin Tissues by Electroacupuncture                                      (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281798/


Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.                                                                   (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168464/?tool=pubmed


Endocannabinoid system in cardiovascular disorders – new pharmacotherapeutic opportunities    (full – 2011)

http://www.jpbsonline.org/article.asp?issn=0975-  7406;year=2011;volume=3;issue=3;spage=350;epage=360;aulast=Cunha


Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice.                                                                       (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109635/?tool=pubmed


Regulatory effect of cannabinoid receptor agonist on chemokine-induced lymphocyte chemotaxis.         (full – 2011)                        https://www.jstage.jst.go.jp/article/bpb/34/7/34_7_1090/_pdf


Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy.     (full – 2011)                                    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161308/


Gadolinium-HU-308-incorporated micelles.              (full – 2011)



Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011)                                  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/


Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. (full – 2011)                                    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137183/?tool=pubmed


CNR2 functional variant (Q63R) influences childhood immune thrombocytopenic purpura.         (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232275/


Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120- induced synapse loss.  (full – 2011)                                   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164336/


The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques                                         (full – 2011)  http://eurheartj.oxfordjournals.org/content/33/7/846.full


The Central Role of Glia in Pathological Pain and the Potential of Targeting the Cannabinoid 2 Receptor for Pain Relief                                                                       (full – 2011)  http://www.hindawi.com/isrn/anesthesiology/2011/593894/









Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone.       (abst – 2011)                            http://www.ncbi.nlm.nih.gov/pubmed/21875957


Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst – 2011)                                        http://marijuana.researchtoday.net/archive/8/1/3517.htm


The role of central CB2 cannabinoid receptors on food intake in neonatal chicks. (abst – 2011)                                   http://www.ncbi.nlm.nih.gov/pubmed/21927979


Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain. (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21550725/abstract/Self_medication_of_a_cannabin




The Type 2 Cannabinoid Receptor Regulates Bone Mass and Ovariectomy-Induced Bone Loss by Affecting Osteoblast Differentiation and Bone Formation                                             (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21447627/abstract/The_Type_2_Cannabinoid_Rec   eptor_Regulates_Bone_Mass_and_Ovariectomy_Induced_Bone_Loss_by_Affecting_Osteoblast_Differenti ation_and_Bone_Formation_


GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21467997/abstract/GPR55_regulates_cannabinoid_  2_receptor_mediated_responses_in_human_neutrophils_


Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization.                                                (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21063029


Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection. (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21873455


Win 55,212-2 reduces cardiac ischaemia-reperfusion injury in zucker diabetic fatty rats: role of cb2 receptors and cardiac inos/enos expression.                                                        (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21309057/abstract/Win_55212_2_reduces_cardiac

_ischaemia_reperfusion_injury_in_zucker_diabetic_fatty_rats:_role_of_cb2_receptors_and_cardiac_inos/e nos_expression_


CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity (abst – 2011)  http://jop.sagepub.com/content/early/2011/03/29/0269881111400652.abstract?maxtoshow=&hits=80&RES  ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcetype=H  WCIT


Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6- hydroxydopamine.          (abst – 2011)                                             http://www.ncbi.nlm.nih.gov/pubmed/20980074









Genetic association between bipolar disorder and 524A>C (Leu133Ile) polymorphism of CNR2 gene, encoding for CB2 cannabinoid receptor.                                                          (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21658778


Cloning and pharmacological characterization of the dog cannabinoid CB2 receptor (abst – 2011)                                   http://www.sciencedirect.com/science/article/pii/S0014299911008788


Brain cannabinoid CB2 receptors modulate cocaine’s actions in mice                (abst – 2011)



G-protein coupled receptors regulating cough.              (abst – 2011)



Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro (abst – 2011)                                        http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01519.x/abstract


Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo.           (abst – 2011)                  http://www.ncbi.nlm.nih.gov/pubmed/21884703


Design and evaluation of a novel fluorescent CB2 ligand as probe for receptor visualization in immune cells.                                                           (abst – 2011)      http://www.ncbi.nlm.nih.gov/pubmed/21855337


Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice. (abst – 2011)                                    http://www.ncbi.nlm.nih.gov/pubmed/21430651


Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects.                                                        (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/22007164/abstract/Endocannabinoid_system_and_ psychiatry:_in_search_of_a_neurobiological_basis_for_detrimental_and_potential_therapeutic_effects_


Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system.         (abst – 2011)                                             http://www.ncbi.nlm.nih.gov/pubmed/22074629


Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization.                                                  (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21063029


Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice                                                        (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21771590/abstract/Antinociceptive_effects_induce  d_through_the_stimulation_of_spinal_cannabinoid_type_2_receptors_in_chronically_inflamed_mice_


Spinal cannabinoid CB2 receptors as a target for neuropathic pain: an investigation using chronic constriction injury.                                                          (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/22210507


Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat

(abst – 2011)











Cannabinoid Receptor 2 Is Critical for the Homing and Retention of Marginal Zone B Lineage Cells and for Efficient T-Independent Immune Responses                                                 (abst – 2011)  http://www.jimmunol.org/content/187/11/5720.abstract?sid=590f7819-f39b-4214-abca-07231b51da55


Cannabinoid-2 Receptor Activation Protects against Infarct and Ischemia/Reperfusion Heart Injury.      (abst – 2011)                         http://www.ncbi.nlm.nih.gov/pubmed/22113346


Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration. (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/20597071/abstract/Beneficial_paracrine_effects_of



Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis.                                                                          (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22119709


The endocannabinoid system in the cancer therapy: an overview.             (abst – 2011)



CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling          (abst – 2011)



Activation of Cannabinoid Type 2 Receptors Inhibits HIV-1 Envelope Glycoprotein gp120-Induced Synapse Loss                                                                 (abst – 2011)  http://molpharm.aspetjournals.org/content/80/3/357.abstract?sid=5a0b0e4c-1879-438e-a131-8829cc6f9bcb


Electroacupuncture reduces the expression of proinflammatory cytokines in inflamed skin tissues through activation of cannabinoid CB2 receptors.                                                                (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22337285


The role of central CB2 cannabinoid receptors on food intake in neonatal chicks (abst – 2011)                                     http://www.ncbi.nlm.nih.gov/pubmed/21927979


Severity of acute cystitis may be cut with cannabinoid agonist               (news – 2011)  http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Severity-of-acute-cystitis-  may-be-cut-with-cannabi/ArticleStandard/Article/detail/747566


Effects of a Selective Cannabinoid CB2 Agonist and Antagonist on Intravenous Nicotine Self Administration and Reinstatement of Nicotine Seeking.                                                      (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266883/?tool=pubmed


Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors? (full – 2012)                                   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419612/


Endocannabinoids Stimulate Human Melanogenesis via Type-1 Cannabinoid Receptor (full – 2012)                                      http://www.jbc.org/content/early/2012/03/19/jbc.M111.314880.full.pdf+html










The role of CB2 receptor ligands in human eosinophil function              (full – 2012)



Cannabinoid Receptor 2-Mediated Attenuation of CXCR4-Tropic HIV Infection in Primary CD4+ T Cells       (full – 2012)  http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033961


Cannabinoids and atherosclerotic coronary heart disease.              (full – 2012)



Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis                                                      (full – 2012)  http://ccforum.com/content/16/2/R47


Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists.        (full – 2012)                                http://onlinelibrary.wiley.com/doi/10.1002/jbmr.1732/full


The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation (full – 2012)                                    http://www.jneuroinflammation.com/content/9/1/79


Cannabinoid modulation of neuroinflammatory disorders.             (full – 2012)



Functional Metabolomics Reveals Novel Active Products in the DHA Metabolome. (full – 2012)                                  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342038/?tool=pubmed


Therapeutic Potentials and uses of Cannabinoid Agonists in Health and Disease Conditions        (full – 2012)                                    http://maxwellsci.com/print/bjpt/v3-76-88.pdf


Role of cannabinoids in the regulation of bone remodeling              (full – 2012)



Early Endogenous Activation of CB1 and CB2 Receptors after Spinal Cord Injury Is a Protective Response Involved in Spontaneous Recovery                                                (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496738/


The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB2 receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy                                                                                           (full – 2012)  http://www.molecularpain.com/content/8/1/71


Small-animal PET imaging of the type 1 and type 2 cannabinoid receptors in a photothrombotic stroke model     (full – 2012)  http://link.springer.com/article/10.1007/s00259-012-2209-6/fulltext.html









Cannabinoid receptor type 2 is time-dependently expressed during skin wound healing in mice.   (full – 2012)                      http://link.springer.com/article/10.1007/s00414-012-0741-3/fulltext.html


GPR18 in microglia: implications for the CNS and endocannabinoid system signaling (full – 2012)                                   http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02019.x/full


Cannabinoids Facilitate the Swallowing Reflex Elicited by the Superior Laryngeal Nerve Stimulation in Rats     (full – 2012)                                http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507745/


Targeting cannabinoid receptor CB(2 ) in cardiovascular disorders: promises and controversies.   (full – 2012)



Endocannabinoids in stressed humans                (link to PDF – 2012)  http://www.doaj.org/doaj?func=abstract&id=1152482&q1=cannabinoid&f1=all&b1=and&q2=&f2=all&re cNo=2&uiLanguage=en


Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. (abst – 2012)                                    http://www.ncbi.nlm.nih.gov/pubmed/22795792


Effect of omega-3 polyunsaturated fatty acids on the endocannabinoid system in osteoblast-like cells and muscle                                                                  (abst – 2012)  http://docs.lib.purdue.edu/dissertations/AAI3444794/


Behavioral effects of pulp exposure in mice lacking cannabinoid receptor 2. (abst – 2012)                                    http://www.ncbi.nlm.nih.gov/pubmed/22152627


Role of cannabinoid 2 receptor in the development of bone cancer pain (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22490961


Review article: Why do cannabinoid receptors have more than one endogenous ligand? (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/23108541


Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection. (abst – 2012)                                    http://www.ncbi.nlm.nih.gov/pubmed/22020035


Cannabinoid CB(2) receptor-mediated regulation of impulsive-like behaviour in DBA/2 mice.     (abst – 2012)                      http://www.ncbi.nlm.nih.gov/pubmed/21671903


Dynamic changes to the endocannabinoid system in models of chronic pain (abst – 2012)                                  http://www.ncbi.nlm.nih.gov/pubmed/23108548


Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6- hydroxydopamine.          (abst – 2012)                                           http://www.ncbi.nlm.nih.gov/pubmed/20980074









Overexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult mice.                                                   (abst – 2012)      http://www.ncbi.nlm.nih.gov/pubmed/22487302


Cannabinoids and muscular pain. Effectiveness of the local administration in rat. (abst – 2012)                                   http://www.ncbi.nlm.nih.gov/pubmed/22354705


Review article: The endocannabinoid system in normal and pathological brain ageing (abst – 2012)                                       http://www.ncbi.nlm.nih.gov/pubmed/23108550


β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner.                                                        (abst – 2012)      http://www.ncbi.nlm.nih.gov/pubmed/22326488


Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats.                                                       (abst – 2012)     http://www.ncbi.nlm.nih.gov/pubmed/22290687


Localization of mGluR5, GABA(B) , GABA(A) , and cannabinoid receptors on the vago- vagal reflex pathway responsible for transient lower esophageal sphincter relaxation in humans: an immunohistochemical study.                                                                                 (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22256945


Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2.                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22366523


Alteration of endocannabinoid system in human gliomas.               (abst – 2012)



The Role of Cannabinoids In Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke.                                                                      (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22420307


Intrathecal cannabilactone CB(2)R agonist, AM1710, controls pathological pain and restores basal cytokine levels.                                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22425445


Cannabinoid receptors in submandibular acinar cells: functional coupling between saliva fluid and electrolytes secretion and Ca2+ signalling.                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22366450


The Cannabinoid Receptor type 2 Q63R variant increases the risk of celiac disease: Implication for a novel molecular biomarker and future therapeutic intervention. (abst – 2012)                                     http://www.sciencedirect.com/science/article/pii/S1043661812000540


The therapeutic potential of the endocannabinoid system for Alzheimer’s disease. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/22448595









Δ(8) -Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB(2) receptors.        (abst – 2012)                                http://www.ncbi.nlm.nih.gov/pubmed/21470208


Anti-proliferative and Anti-angiogenic Effects of CB2R Agonist (JWH-133) in Non- small Lung Cancer Cells (A549) and Human Umbilical Vein Endothelial Cells: an in Vitro Investigation.    (abst – 2012)                                               http://www.ncbi.nlm.nih.gov/pubmed/22578958


Role of Lipid Rafts/Caveolae in the Anticancer Effect of Endocannabinoids. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/22625418


Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?                                              (abst – 2012)         http://www.ncbi.nlm.nih.gov/pubmed/22625422


Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis.                                         (abst – 2012)       http://www.ncbi.nlm.nih.gov/pubmed/22738050


Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22553354


Cannabinoid 2 (CB2) Receptor Involvement in the Down-regulation but not Up- regulation of Serum IgE Levels in Immunized Mice.                                                                       (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22552780


Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22532560


Prevention of Paclitaxel-Induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System                                                                 (abst – 2012)

http://www.anesthesia- analgesia.org/content/114/5/1104.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext=cannabi  noid&searchid=1&FIRSTINDEX=130&sortspec=date&resourcetype=HWCI



http://www.bjjprocs.boneandjoint.org.uk/content/94-  B/SUPP_XVIII/7.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext=cannabinoid&searchid= 1&FIRSTINDEX=130&sortspec=date&resourcetype=HWCIT


Cannabinoid receptor-2-selective agonists improve recovery in experimental autoimmune encephalomyelitis                                             (abst – 2012)  http://www.jimmunol.org/cgi/content/meeting_abstract/188/1_MeetingAbstracts/116.7?maxtoshow=&hits

=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&resou  rcetype=HWCIT


CB(2) receptor and amyloid pathology in frontal cortex of Alzheimer’s disease patients. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/22763024










Cannabinoid receptor 2 agonists inhibit migration of activated dendritic cells via modulation of MMP-9 (abst – 2012)  http://www.jimmunol.org/cgi/content/meeting_abstract/188/1_MeetingAbstracts/173.23?maxtoshow=&hits

=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&resou  rcetype=HWCIT


Cannabinoid receptors in submandibular acinar cells: Functional coupling between saliva fluid and electrolytes secretion and Ca2+ signalling                                                    (abst – 2012)  http://jcs.biologists.org/content/125/8/1884.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext



Discovery and optimization of novel purines as potent and selective CB2 agonists. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22765893


Therapeutic modulation of cannabinoid lipid signaling: Metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist.                                                                 (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22749867


Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat

(abst – 2012)



The Expression and Significance of Cannabinoid Receptor 2 in Non-infectious Granuloma and Malignant Melanoma                                                             (abst – 2012)



Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions.                                                       (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22442067


Spinal Cord Fatty Acid Amide Hydrolase (FAAH) in Normal Micturition Control and Bladder Overactivity in Awake Rats.                                                             (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23219540


Excitability of prefrontal cortical pyramidal neurons is modulated by activation of intracellular type-2 cannabinoid receptors.                                                                        (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22331871


Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB(1) and CB(2) Receptors.        (abst – 2012)                               http://www.ncbi.nlm.nih.gov/pubmed/22860209


A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury. (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22903455









Expression of fatty acid amide hydrolase (FAAH) in human, mouse, and rat urinary bladder and effects of FAAH inhibition on bladder function in awake rats.                                                           (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/21930339


Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic Fatty liver disease.                                                        (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22927922


Genetic variability in the endocannabinoid system and 12-week clinical response to citalopram treatment: the role of the CNR1, CNR2 and FAAH genes                                                                  (abst – 2012)  http://jop.sagepub.com/content/early/2012/07/22/0269881112454229.abstract?maxtoshow=&hits=80&RES  ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=H WCIT


Signaling through cannabinoid receptor 2 suppresses murine dendritic cell migration by inhibiting matrix metalloproteinase 9 expression.                                         (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22972984


The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB2 receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy.                                                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22998838


The therapeutic potential of cannabis and cannabinoids.              (abst – 2012)



Anandamide enhances expression of heat shock protein 72 to protect against ischemia- reperfusion injury in rat heart.                                                    (abst – 2012)     http://www.ncbi.nlm.nih.gov/pubmed/23007622


Cannabinoid Receptor Subtypes 1 and 2 Mediate Long-Lasting Neuroprotection and Improve Motor Behaviour Deficits After Transient Focal Cerebral Ischemia.

(abst – 2012)               http://www.ncbi.nlm.nih.gov/pubmed/23069763


4-Oxo-1,4-dihydropyridines as Selective CB2 Cannabinoid Receptor Ligands Part 2: Discovery of New Agonists Endowed with Protective Effect Against Experimental Colitis.      (abst – 2012)                         http://www.ncbi.nlm.nih.gov/pubmed/23017078


Differences in the endocannabinoid system of sperm from fertile and infertile men. (abst – 2012)                                   http://www.ncbi.nlm.nih.gov/pubmed/23082196


Chronic activation of cannabinoid receptors in vitro does not compromise mouse islet function.   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23078523


Distribution and function of the endocannabinoid system in the rat and human bladder. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/23081739


Cannabinoid drugs can directly inhibit HIV in late-stage AIDS               (news – 2012)









http://www.news-medical.net/news/20120321/Cannabinoid-drugs-can-directly-inhibit-HIV-in-late-stage-  AIDS.aspx


Cannabinoid 2 receptors regulate impulsive behavior                (news – 2012)



Involvement of peripheral cannabinoid and opioid receptors in β-caryophyllene-induced antinociception.                                        (abst – 2012)         http://www.ncbi.nlm.nih.gov/pubmed/23138934


Activation of Cannabinoid Receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23139224


△9-Tetrahydrocannabinol Impairs the Inflammatory Response to Influenza Infection:

Role of Antigen Presenting Cells and the Cannabinoid Receptors 1 and 2.            (abst – 2012)



Impact of reference gene selection for type 2 cannabinoid receptor gene expression studies in human spermatozoa                                                                (abst – 2012)  http://onlinelibrary.wiley.com/doi/10.1111/and.12006/abstract


Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes.                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22701012?dopt=Abstract


Anandamide Induces Matrix Metalloproteinase-2 Production through Cannabinoid-1 Receptor and Transient Receptor Potential Vanilloid-1 in Human Dental Pulp Cells in Culture       (abst – 2012)                       http://www.jendodon.com/article/PIIS0099239912002191/abstract?rss=yes


Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice.                                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/21883147


Endocannabinoid system and mood disorders: Priming a target for new therapies. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/23261685


Cannabinoid receptors: nomenclature and pharmacological principles.              (abst – 2012)



CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation                                                        (abst – 2012)  http://onlinelibrary.wiley.com/doi/10.1002/glia.22366/abstract


Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate.                                                       (abst – 2012)        http://www.ncbi.nlm.nih.gov/pubmed/23199705


Cannabinoid Receptor 2 Signaling in Peripheral Immune Cells Modulates Disease Onset and Severity in Mouse Models of Huntington’s Disease.                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23238740










Update on the endocannabinoid-mediated regulation of gelatinase release in arterial wall physiology and atherosclerotic pathophysiology.                                         (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23253273


Prevention of paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system.                                                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22392969


Cannabinoid Receptor Stimulator Reverses Symptoms of Alzheimer’s Disease in Animal Model  (news – 2012)                         http://www.biotechdaily.com/?option=com_article&Itemid=294742494


Researchers investigating potential drug for treatement of Alzheimer’s disease (news – 2012)



CB1 and CB2 Cannabinoid Receptor Agonists Induce Peripheral Antinociception by Activation of the Endogenous Noradrenergic System.                                        (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23302980


Differential Expression of Intracellular and Extracellular CB(2) Cannabinoid Receptor Protein by Human Peripheral Blood Leukocytes.                                                                (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23299999


The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects.                                         (abst – 2013)         http://www.ncbi.nlm.nih.gov/pubmed/23296873


Cannabinoid Receptors as Therapeutic Targets for Dialysis-Induced Peritoneal Fibrosis. (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23296044


LiCABEDS II. Modeling of Ligand Selectivity for G-protein Coupled Cannabinoid Receptors.   (abst – 2013)                              http://www.ncbi.nlm.nih.gov/pubmed/23278450


Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. (abst – 2013)                                      http://www.ncbi.nlm.nih.gov/pubmed/22795792


CB(2) receptor and amyloid pathology in frontal cortex of Alzheimer’s disease patients. (abst – 2013)                                      http://www.ncbi.nlm.nih.gov/pubmed/22763024


Evidence for the involvement of cannabinoid receptors’ polymorphisms in the pathophysiology of human diseases.                                                                          (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23293857


Behavioral Responses to Acute and Sub-chronic Administration of the Synthetic Cannabinoid JWH-018 in Adult Mice Prenatally Exposed to Corticosterone. (abst – 2013)   http://www.ncbi.nlm.nih.gov/pubmed/23296549


Cannabinoid receptor 2 is upregulated in melanoma.                (abst – 2013)











Δ9-tetrahydrocannabinol impairs the inflammatory response to influenza infection: role of antigen-presenting cells and the cannabinoid receptors 1 and 2.                                                                   (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23152191


The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis.                                                                       (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23373571


The pharmacologic and clinical effects of medical cannabis.                       (abst – 2013)



Cannabinoid CB2 receptor gene (CNR2) polymorphism is associated with chronic childhood immune thrombocytopenia in Egypt.                                                  (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23406660


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