CBR– CB1 CANNABINOID RECEPTOR -activated by THC, Anandamide, synthetics


Cannabinoid Receptor Ligands                     (full – undated)



Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor. (abst – 1992)                                             http://www.ncbi.nlm.nih.gov/pubmed/1470919


Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide.      (abst – 1995)                                http://www.ncbi.nlm.nih.gov/pubmed/7589169


The CB1 cannabinoid receptor antagonist SR 141716A affects A9 dopamine neuronal activity in the rat.                                                  (abst – 1995)       http://www.ncbi.nlm.nih.gov/pubmed/7488739


Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder (full – 1996)                                        http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1909890/


Marijuana and chocolate.                   (abst – 1996)       http://www.ncbi.nlm.nih.gov/pubmed/11363932


Cannabinoid-Induced Hypotension and Bradycardia in Rats Is Mediated by CB1-Like Cannabinoid Receptors  (full – 1997)  http://jpet.aspetjournals.org/content/281/3/1030.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext



Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. (abst – 1997)                                             http://www.ncbi.nlm.nih.gov/pubmed/9394002


Hypoactivity of the Spinal Cannabinoid System Results in NMDA-Dependent Hyperalgesia       (full – 1998)                                          http://www.jneurosci.org/content/18/1/451.long


Cardiovascular actions of cannabinoids and their generation during shock.                  (abst – 1998)



Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor (full – 1999)                                          http://www.jbc.org/content/274/5/2794.long


Increased Mortality, Hypoactivity, and Hypoalgesia in Cannabinoid Cb1 Receptor Knockout Mice.        (full – 1999)                                         http://www.pnas.org/content/96/10/5780.long


Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors (abst – 1999)                                  http://link.springer.com/article/10.1007%2Fs002130050953


Cannabis and cannabinoids: pharmacology and rationale for clinical use                (abst – 1999)



Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain.                                                    (abst – 1999)  http://www.ncbi.nlm.nih.gov/pubmed/10594647?dopt=Abstract


Thujone exhibits low affinity for cannabinoid receptors but fails to evoke cannabimimetic responses.       (abst – 1999)                       http://www.ncbi.nlm.nih.gov/pubmed/10080239


Endocannabinoids and Vascular Function              (full – 2000)



Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human                                                              (full – 2000)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571997/?tool=pmcentrez


Modulation of peristalsis by cannabinoid CB1 ligands in the isolated guinea-pig ileum (full – 2000)                                  http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1571902&tool=pmcentrez


2-Arachidonoylglycerol and the cannabinoid receptors.                (abst – 2000)



Cannabinoid CB1-mediated inhibition of stress-induced gastric ulcers in rats (abst – 2000)                                     http://www.springerlink.com/content/w3jc8rk16k9p92fl/


Inhibition of small intestinal secretion by cannabinoids is CB1 receptor-mediated in rats (abst – 2000)                                      http://www.sciencedirect.com/science/article/pii/S0014299900008438


Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland.                                                  (abst – 2000)     http://www.ncbi.nlm.nih.gov/pubmed/10733937


Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia        (abst – 2000)                                      http://www.ncbi.nlm.nih.gov/pubmed/11204352


Are Cannabinoid Receptor Knockout Mice Animal Models for Schizophrenia?

(abst – 2000)               http://www.medical-hypotheses.com/article/S0306-9877%2800%2991261-1/abstract


CB1 cannabinoid receptor expression in brain regions associated with zebra finch song control.   (abst – 2000)                            http://www.ncbi.nlm.nih.gov/pubmed/10700562


Delta(9)-tetrahydrocannabinol and synthetic cannabinoids prevent emesis produced by the cannabinoid CB(1) receptor antagonist/inverse agonist SR 141716A.                                                   (full – 2001)  http://www.nature.com/npp/journal/v24/n2/full/1395605a.html



Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation                                                 (full – 2001)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572987/?tool=pmcentrez


Endogenous cannabinoids mediate hypotension after experimental myocardial infarction (full – 2001)  http://content.onlinejacc.org/cgi/content/full/38/7/2048?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=cannabinoid&searchid=1&FIRSTINDEX=560&resourcetype=HWCIT


2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor (full – 2001)                                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC31108/


Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase                                                      (full – 2001)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC55427/?tool=pubmed


Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB(1) receptor-dependent G-protein activation in rat cerebellar membranes. (full – 2001)                                    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572991/?tool=pubmed


The neurobiology and evolution of cannabinoid signalling               (abst – 2001)  http://rstb.royalsocietypublishing.org/content/356/1407/381.abstract?ijkey=3aad97283bf56bae0ada89fe6c2  5ef27a702e9ba&keytype2=tf_ipsecsha


The Central Cannabinoid Receptor Inactivation Suppresses Endocrine Reproductive Functions.  (abst – 2001)                                http://www.ncbi.nlm.nih.gov/pubmed/11394887


Sourcing the Code: Searching for the Evolutionary Origins of Cannabinoid Receptors, Vanilloid Receptors, and Anandamide                                                          (full – 2002)



A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding       (full – 2002)  http://www.jneurosci.org/cgi/content/abstract/22/21/9612?ijkey=328b5e83d7be9297b9483d22e0d6319fa0a 862e8&keytype2=tf_ipsecsha


Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN-55212-2 or HU 210 in conscious rats                                                      (full – 2002)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573379/?tool=pmcentrez


Increased Severity of Stroke in CB1 Cannabinoid Receptor Knock-Out Mice (full – 2002)

http://www.jneurosci.org/cgi/content/full/22/22/9771?maxtoshow=&hits=80&RESULTFORMAT=&fullte   xt=cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT#Top


Loss of cannabinoid CB(1) receptors in the basal ganglia in the late akinetic phase of rats with experimental Huntington’s disease.                                              (abst – 2002)  http://www.ncbi.nlm.nih.gov/pubmed/12709298



The endogenous cannabinoid system controls extinction of aversive memories. (abst – 2002)                                       http://www.ncbi.nlm.nih.gov/pubmed/12152079


Association of a CB1 cannabinoid receptor gene (CNR1) polymorphism with severe alcohol dependence.                                                (abst – 2002)       http://www.ncbi.nlm.nih.gov/pubmed/11841893


Marijuana receptor gene abnormality in schizophrenia                (news – 2002)



Differential Roles of CB1 and CB2 Cannabinoid Receptors in Mast Cells            (full – 2003)



CB1 cannabinoid receptor antagonism promotes remodeling and cannabinoid treatment prevents endothelial dysfunction and hypotension in rats with myocardial infarction (full – 2003)                                  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573770/?tool=pmcentrez


Endocannabinoid signalling in the blood of patients with schizophrenia (full – 2003)                                                  http://www.lipidworld.com/content/2/1/5


The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy                                                        (full – 2003)  http://jpet.aspetjournals.org/content/307/1/129.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=  cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT


The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis                                                          (full – 2003)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166293/


Cannabinoid1 receptor in the dorsal vagal complex modulates lower oesophageal sphincter relaxation in ferrets  (full – 2003)                                                 http://jp.physoc.org/content/550/1/149.full


Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon         (full – 2003)



Association between cannabinoid receptor gene (CNR1) and childhood attention deficit/hyperactivity disorder in Spanish male alcoholic patients (full – 2003)  http://www.nature.com/mp/journal/v8/n5/full/4001278a.html


Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis1 (full – 2003)          http://www.fasebj.org/cgi/reprint/17/12/1771


High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma                                                           (abst – 2003)  http://www.ncbi.nlm.nih.gov/pubmed/12970790


Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract.           (abst – 2003)                                    http://www.ncbi.nlm.nih.gov/pubmed/12505538


Milk intake and survival in newborn cannabinoid CB1 receptor knockout mice: evidence for a “CB3” receptor.                                                 (abst – 2003)        http://www.ncbi.nlm.nih.gov/pubmed/12568912


Expression of functionally active cannabinoid receptor CB1 in the human prostate gland (abst – 2003)                                      http://onlinelibrary.wiley.com/doi/10.1002/pros.10165/abstract


Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271.                                                   (abst – 2003)



Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington’s disease transgenic mice.                                                                    (full – 2004)  http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.2004.04460.x/full


Presynaptic cannabinoid CB1 receptors are involved in the inhibition of the neurogenic vasopressor response during septic shock in pithed rats                                                              (full – 2004)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575049/?tool=pmcentrez


Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice.             (full – 2004)



CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity                                                   (full – 2004)  http://www.nature.com/ijo/journal/v28/n4/full/0802583a.html


Human cannabinoid receptor 1: 5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse.                                                           (full – 2004)  http://www.nature.com/mp/journal/v9/n10/full/4001560a.html


Delayed onset of Huntington’s disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors.                                           (abst – 2004)  http://www.ncbi.nlm.nih.gov/pubmed/14667455


Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene. (abst – 2004)                                      http://www.ncbi.nlm.nih.gov/pubmed/15108190


[123I]AM281 single-photon emission computed tomography imaging of central cannabinoid CB1 receptors before and after Delta9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in tourette patients.

(abst – 2004)                    http://www.ncbi.nlm.nih.gov/pubmed/15110734


TRPV1 and CB(1) receptor-mediated effects of the endovanilloid/endocannabinoid N- arachidonoyl-dopamine on primary afferent fibre and spinal cord neuronal responses in the rat.           (abst – 2004)                        http://www.ncbi.nlm.nih.gov/pubmed/15245490


Cb(1) Receptor Mediation of Cannabinoid Behavioral Effects in Male and Female Rats. (abst – 2004)                                    http://www.ncbi.nlm.nih.gov/pubmed/14991224


Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice                                                 (abst – 2004)

http://onlinelibrary.wiley.com/doi/10.1111/j.1460-  9568.2004.03293.x/abstract;jsessionid=15C92BB3498FAF0EE40394675E8B1800.d01t01


Overeating, Alcohol and Sucrose Consumption Decrease in Cb1 Receptor Deleted Mice. (abst – 2004)                                    http://www.ncbi.nlm.nih.gov/pubmed/12770700


On the Cannabinoid Receptor: A Study in Molecular Psychiatry             (full – 2005)



Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full – 2005)                                     http://www.nature.com/npp/journal/v30/n3/full/1300655a.html


Depression in Parkinson’s disease is related to a genetic polymorphism of the cannabinoid receptor gene (CNR1)                                                                         (full – 2005)  http://www.nature.com/tpj/journal/v5/n2/full/6500301a.html


Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala                                                          (full – 2005)  http://www.nature.com/npp/journal/v30/n3/full/1300535a.html


Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity                                              (full – 2005)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087161/?tool=pmcentrez


The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis.        (full – 2005)                              https://www.jstage.jst.go.jp/article/tjem/207/2/207_2_99/_pdf


Direct cerebrovascular effects of CB1 receptor activation by the synthetic endocannabinoid HU-210 in vivo      (full – 2005)  http://www.nature.com/jcbfm/journal/v25/n1s/full/9591524.0581a.html


CB1 cannabinoid receptor-mediated modulation of food intake in mice               (full – 2005)



Evidence that the plant cannabinoid Δ9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist                                                      (full – 2005)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751228/?tool=pubmed


Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. (full – 2005)                                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1266095/?tool=pubmed


Antidepressant-like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis.                                                       (full – 2005)  http://www.pnas.org/content/102/51/18620.long


Ethanol Induces Higher Bec in Cb1 Cannabinoid Receptor Knockout Mice While Decreasing Ethanol Preference.                                                                   (full – 2005)  http://alcalc.oxfordjournals.org/content/40/1/54.long


Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: role of cannabinoid and vanilloid receptors                                                         (full – 2005)  http://gut.bmj.com/content/54/4/522.full?sid=0731f0e5-2071-4549-be57-57f444307138


The endocannabinoid system drives neural progenitor proliferation.                (full – 2005)



Analgesia through endogenous cannabinoids                (full – 2005)  http://www.cmaj.ca/cgi/content/full/173/4/357?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=end  ocannabinoid&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=date&resourcetype=HW   CIT


Interaction between gamma-aminobutyric acid GABAB and cannabinoid CB1 receptors in spinal pain pathways in rat                                                             (abst – 2005)  http://www.sciencedirect.com/science/article/pii/S0014299905003870


The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors            (abst – 2005)                    http://www.sciencedirect.com/science/article/pii/S0014299905013178


The Endogenous Cannabinoid System. Therapeutic Implications for Neurologic and Psychiatric Disorders                                                  (abst – 2005)          http://www.ncbi.nlm.nih.gov/pubmed/15776259


Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation.       (abst – 2005)                        http://www.ncbi.nlm.nih.gov/pubmed/15953683


Finding of endocannabinoids in human eye tissues: implications for glaucoma. (abst – 2005)                                      http://www.ncbi.nlm.nih.gov/pubmed/15823551


Marijuana May Grow Neurons in the Brain                  (news – 2005)



The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus (full – 2006)                                    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769341/?tool=pmcentrez


AM 251 produces sustained reductions in food intake and body weight that are resistant to tolerance and conditioned taste aversion                                            (full – 2006)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615836/?tool=pmcentrez


Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and Status Epilepticus        (full – 2006)  http://jpet.aspetjournals.org/content/317/3/1072.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext



Activation of G-proteins in brain by endogenous and exogenous cannabinoids. (full – 2006)                                       http://www.ncbi.nlm.nih.gov/pubmed/16584117


The Cannabinoid Cb1 Receptor Antagonist Rimonabant Attenuates the Hypotensive Effect of Smoked Marijuana in Male Smokers.                                                               (full – 2006)  http://www.ahjonline.com/article/S0002-8703%2805%2901013-6/fulltext


Cannabinoid (CB1) Receptor Activation Inhibits Trigeminovascular Neurons (full – 2006)

http://jpet.aspetjournals.org/content/320/1/64.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c  annabis&searchid=1&FIRSTINDEX=3680&resourcetype=HWCIT


Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy                                                                (full – 2006)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808496/?tool=pmcentrez


Antinociceptive effect of cannabinoid agonist WIN 55,212–2 in rats with a spinal cord injury     (full – 2006)                       http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861843/?tool=pmcentrez


Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling          (full – 2006)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238031/?tool=pmcentrez


Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis (full – 2006)

http://www.fasebj.org/cgi/reprint/02-  1129fjev1?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=cannabinoid&andorexactfulltext=and&s   earchid=1&FIRSTINDEX=10&sortspec=relevance&resourcetype=HWCIT


Cannabinoid CB1 Receptor Mediates Fear Extinction via Habituation-Like Processes (full – 2006)  http://www.jneurosci.org/cgi/content/full/26/25/6677?maxtoshow=&hits=80&RESULTFORMAT=&fullte   xt=cannabinoid&searchid=1&FIRSTINDEX=400&resourcetype=HWCIT


Evolutionary Origins of the Endocannabinoid System.             (abst – 2006)



(AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population                                                      (abst – 2006)  http://pharmgkb.org/pmid/16314880


Neuromodulatory functions of the endocannabinoid system.               (abst – 2006)



Science: Cannabinoids reduce inflammation of the bowel in animal model (news – 2006)



PET imaging of cerebral cannabinoid CB1 receptors with [11C]JHU75528 (news – 2006)                http://www.news-medical.net/news/2006/06/06/18312.aspx


The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.       (full – 2007)                              http://www.fasebj.org/cgi/content/full/22/1/285


Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner                                                        (full – 2007)  http://www.jbc.org/content/283/10/6005.full?sid=931583b1-e797-43e0-8296-7fd75bb49403#sec-4





Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men.                                                           (full – 2007)  http://jcem.endojournals.org/content/92/6/2382.long


Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors           (full – 2007)                       http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234438/


The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis                                                               (full – 2007)       http://www.jbc.org/content/282/33/23892.full


Expression of Cannabinoid CB1 Receptors in Models of Diabetic Neuropathy (full – 2007)

http://jpet.aspetjournals.org/content/323/2/508.full?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=  cannabinoid&searchid=1&FIRSTINDEX=320&resourcetype=HWCIT


Cannabinoid CB1 and CB2 Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Subtypes in Human Multiple Sclerosis                                                      (full – 2007)  http://www.jneurosci.org/cgi/content/full/27/9/2396?maxtoshow=&hits=10&RESULTFORMAT=&fulltext




Cannabinoid action in the olfactory epithelium              (full – 2007)



Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson’s disease: role of CB1 and TRPV1 receptors                                                   (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128772/?tool=pmcentrez


Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors.  (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189718/?tool=pubmed


Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats (full – 2007)                                  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190006/?tool=pmcentrez


Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro      (full – 2007)  http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2189767&tool=pmcentrez


Anandamide Regulates Keratinocyte Differentiation by Inducing DNA Methylation in a CB1 Receptor-dependent Manner                                                      (full – 2007)     http://www.jbc.org/content/283/10/6005.full


Virodhamine and CP55,940 modulate cAMP production and IL-8 release in human bronchial epithelial cells.     (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2042924/?tool=pubmed


The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. (abst – 2007)   http://www.ncbi.nlm.nih.gov/pubmed/17583570


Effect of Endocannabinoid System on the Neurogenic Function of Rat Corpus Cavernosum  (abst – 2007)  http://www.doaj.org/doaj?func=abstract&id=1150200&q1=endocannabinoid%20system&f1=all&b1=and&  q2=&f2=all&recNo=26&uiLanguage=en


Effects of AM1346, a high-affinity CB1 receptor selective anandamide analog, on open- field behavior in rats.                                                 (abst – 2007)       http://www.ncbi.nlm.nih.gov/pubmed/17912052


Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance                                                                    (abst – 2007)  http://www.ncbi.nlm.nih.gov/pubmed/17320118


The local antinociceptive effects of paracetamol in neuropathic pain are mediated by cannabinoid receptors                                                   (abst – 2007)  http://www.sciencedirect.com/science/article/pii/S0014299907007935


Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies                             (abst – 2007)  http://www.ncbi.nlm.nih.gov/pubmed/17507169


In Vitro Anticonvulsant Action of 2-Arachidonyl Glycerol                   (abst – 2007)  http://www.doaj.org/doaj?func=abstract&id=463469&q1=anandamide&f1=all&b1=and&q2=&f2=all&rec No=29&uiLanguage=en


The endocannabinoid system and neurogenesis in health and disease.               (abst – 2007)




Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret.                                                    (abst – 2007)  http://www.ncbi.nlm.nih.gov/pubmed/17459108


No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents.                                                           (abst – 2007)  http://www.ncbi.nlm.nih.gov/pubmed/17292652


Whole-Body Biodistribution and Radiation Dosimetry of the Human Cannabinoid Type- 1 Receptor Ligand ^sup 18^F-MK-9470 in Healthy Subjects                                                        (full – 2008)  http://jnm.snmjournals.org/content/49/3/439.long


Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men                                                        (full – 2008)  http://jcem.endojournals.org/cgi/content/full/92/6/2382


Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations                                                         (full – 2008)  http://hmg.oxfordjournals.org/content/17/13/1916.long


Cannabinoid Receptor 1 Gene Association With Nicotine Dependence               (full – 2008)  http://archpsyc.ama- assn.org/cgi/content/full/65/7/816?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&se  archid=1&FIRSTINDEX=0&resourcetype=HWCIT


Association of the Cannabinoid Receptor Gene (CNR1) With ADHD and Post-Traumatic Stress Disorder          (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685476/?tool=pubmed


The cannabinoid CB1 receptor antagonist CE prolongs spatial memory duration in a rat delayed radial arm maze memory task                                                       (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577903/?tool=pmcentrez


Cannabinoid Modulation of Cutaneous A{delta} Nociceptors During Inflammation (full – 2008)                                       http://jn.physiology.org/cgi/reprint/100/5/2794


Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor-Mediated Mechanism of Action                                                                   (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637200/?tool=pmcentrez


The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9- tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin                                                     (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219532/


Loss of Cannabinoid Receptor CB1 Induces Preterm Birth                  (full – 2008)



Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning          (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219536/?tool=pmcentrez


Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: growth inhibition by receptor activation.                                                                 (full – 2008)  http://onlinelibrary.wiley.com/doi/10.1002/ijc.23584/full


Pharmacological Inhibition of CB1 Cannabinoid Receptor Protects Against Doxorubicin- Induced Cardiotoxicity                                                    (full – 2008)        http://content.onlinejacc.org/cgi/content/full/50/6/528


Cannabinoid receptors and the regulation of bone mass                 (full – 2008)



Loss of cannabinoid receptor 1 accelerates intestinal tumor growth                (full – 2008)



Cannabinoid CB1 Receptors Are Expressed by Parietal Cells of the Human Gastric Mucosa        (full – 2008)                              http://jhc.sagepub.com/content/56/5/511.full


Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages         (full – 2008)  http://cardiovascres.oxfordjournals.org/content/81/4/805.full?sid=7d2438c4-a727-410f-870d-  4a971695b4fb


Expression of the Endocannabinoid System in Human First Trimester Placenta and Its Role in Trophoblast Proliferation                                                       (full – 2008)  http://endo.endojournals.org/content/149/10/5052.full?sid=f5b14012-9fbe-4f10-890c-386313060cf8


Feeding induced by cannabinoids is mediated independently of the melanocortin system. (full – 2008)                                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386290/?tool=pubmed


Design Logic of a Cannabinoid Receptor Signaling Network That Triggers Neurite Outgrowth    (full – 2008)                             http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776723/?tool=pubmed


Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs.          (abst – 2008)                         http://www.ncbi.nlm.nih.gov/pubmed/18266975


The role of the CB1 receptor in the regulation of sleep.                (abst – 2008)



The modulatory role of endocannabinoids in sleep                 (abst – 2008)



Peripheral cannabinoid CB1 receptors inhibit evoked responses of nociceptive neurones in vivo   (abst – 2008)                            http://www.sciencedirect.com/science/article/pii/S0014299908002719


Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET.                                                       (abst – 2008)  http://www.ncbi.nlm.nih.gov/pubmed/18077184


Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum.      (abst – 2008)                         http://www.ncbi.nlm.nih.gov/pubmed/18204441


Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET.                                                      (abst – 2008)  http://www.ncbi.nlm.nih.gov/pubmed/18077184?dopt=Abstract


Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity.                                              (abst – 2008)  http://www.ncbi.nlm.nih.gov/pubmed/18279310


Dysregulation of the endocannabinoid system in obesity.                 (abst – 2008)



Effect of anandamide in improving of the non-adrenergic non-cholinergic relaxation of the corpus cavernosum from diabetic rats                                                              (abst – 2008)  http://www.doaj.org/doaj?func=abstract&id=859448&q1=anandamide&f1=all&b1=and&q2=&f2=all&rec  No=25&uiLanguage=en


Effect of biliary cirrhosis on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum: Role of nitric oxide pathway and endocannabinoid system

(abst – 2008)  http://www.doaj.org/doaj?func=abstract&id=859538&q1=anandamide&f1=all&b1=and&q2=&f2=all&rec No=24&uiLanguage=en


High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells. (abst – 2008)                                     http://www.ncbi.nlm.nih.gov/pubmed/18615640


Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth (news – 2008)                                       http://www.sciencedaily.com/releases/2008/08/080801074056.htm


Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer        (news – 2008)                                http://www.news-medical.net/news/2008/08/03/40485.aspx



(news – 2008)                http://jama.jamanetwork.com/article.aspx?articleid=182826


Actions of delta-9-tetrahydrocannabinol in cannabis             (full – 2009)



Cannabinoid Receptor 1 Binding Activity and Quantitative Analysis of Cannabis sativa

L. Smoke and Vapor           (full – 2009)      https://www.jstage.jst.go.jp/article/cpb/58/2/58_2_201/_pdf


Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory                                                     (full – 2009)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660732/?tool=pmcentrez


The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine                                             (full – 2009)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757501/


Endocannabinoid-mediated control of synaptic transmission.                (full – 2009)



Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis                                                                      (full – 2009)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688760/?tool=pubmed


The CB1/CB2 receptor agonist WIN-55,212-2 reduces viability of human Kaposi’s sarcoma cells in vitro            (full – 2009)  http://science.iowamedicalmarijuana.org/pdfs/cancer/Luca%20et%20al%202009%2019539619.pdf


Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon                                                           (full – 2009)  http://ajpgi.physiology.org/cgi/content/full/296/1/G119?maxtoshow=&hits=80&RESULTFORMAT=&full text=cannabinoid&searchid=1&FIRSTINDEX=160&resourcetype=HWCIT


Characterization of the Endocannabinoid System in Human Neuronal Cells and Proteomic Analysis of Anandamide-induced Apoptosis                                                     (full – 2009)  http://www.jbc.org/content/284/43/29413.full


Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma       (full – 2009)                                  http://mct.aacrjournals.org/content/8/7/1838.full


Microglial CB2 cannabinoid receptors are neuroprotective in Huntington’s disease excitotoxicity.            (full – 2009)                           http://brain.oxfordjournals.org/content/132/11/3152.long


Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats.                                                           (full – 2009)  http://www.if-pan.krakow.pl/pjp/pdf/2009/2_304.pdf


Voluntary Exercise and Sucrose Consumption Enhance Cannabinoid CB1 Receptor Sensitivity in the Striatum   (full – 2009)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055381/?tool=pubmed


Relationship of type 1 cannabinoid receptor availability in the human brain to novelty- seeking temperament.      (full – 2009)                                     http://archpsyc.ama-assn.org/cgi/content/full/66/2/196


Impairments in Endocannabinoid Signaling and Depressive Illness                 (full – 2009)



CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages                                              (full – 2009)  http://cardiovascres.oxfordjournals.org/content/84/3/378.full?sid=7d2438c4-a727-410f-870d-  4a971695b4fb


Endocannabinoid signalling as an anti-inflammatory therapeutic target in atherosclerosis: does it work?   (full – 2009)  http://cardiovascres.oxfordjournals.org/content/84/3/341.full?sid=7d2438c4-a727-410f-870d-  4a971695b4fb


Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development   (full – 2009)                                     http://www.rbej.com/content/7/1/121


Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications.                                                         (abst – 2009)  http://www.ncbi.nlm.nih.gov/pubmed/19897083


Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas.                                                         (abst – 2009)  http://www.sciencedirect.com/science/article/pii/S0006899308030588


Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington’s disease.                                                            (abst – 2009)  http://www.ncbi.nlm.nih.gov/pubmed/19524019


Bidirectional regulation of novelty-induced behavioral inhibition by the endocannabinoid system.           (abst – 2009)                 http://www.ncbi.nlm.nih.gov/pubmed/19607846


The cannabinoid system: cannabinoids and receptors               (news – 2009)  http://www.examiner.com/health-science-in-vancouver/the-cannabinoid-system-cannabinoids-and-  receptors


Endocannabinoid Overload                 (full – 2010)



International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2                                                             (full – 2010)  http://pharmrev.aspetjournals.org/content/62/4/588.full.pdf+html


Understanding Functional Residues of the Cannabinoid CB1 for Drug Discovery. (full – 2010)                                      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980537/?tool=pubmed


Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism (full – 2010)                                       http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260554/?tool=pubmed


The Cannabinoid 1 Receptor (CNR1) 1359 G/A Polymorphism Modulates Susceptibility to Ulcerative Colitis and the Phenotype in Crohn’s Disease                                                         (full – 2010)




A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain.                                                         (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013130/?tool=pubmed


Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype                                                           (full – 2010)  http://ajpgi.physiology.org/content/299/1/G63.full?sid=fc6948f0-78cf-405c-981b-afaa05ee417c


Cannabinoid–Dopamine Interaction in the Pathophysiology and Treatment of CNS Disorders     (full – 2010)                           http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5949.2010.00144.x/full


Voluntary Exercise and Sucrose Consumption Enhance Cannabinoid CB1 Receptor Sensitivity in the Striatum   (full – 2010)  http://www.nature.com/npp/journal/v35/n2/full/npp2009141a.html


Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis                                                                 (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898685/?tool=pubmed


Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome.            (full – 2010)                              http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906112/


Preservation of Striatal Cannabinoid CB1 Receptor Function Correlates with the Antianxiety Effects of Fatty Acid Amide Hydrolase  Inhibition                                                                       (full – 2010)  http://molpharm.aspetjournals.org/content/78/2/260.long


AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity.                                                 (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006205/?tool=pubmed


Widespread Decrease of Type 1 Cannabinoid Receptor Availability in Huntington Disease In Vivo         (full – 2010)                                   http://jnm.snmjournals.org/cgi/content/full/51/9/1413


JWH018, a common constituent of ‘Spice’ herbal blends, is a potent and efficacious cannabinoid CB(1) receptor agonist.                                                               (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931559/?tool=pubmed


Attenuation of morphine antinociceptive tolerance by a CB(1) receptor agonist and an NMDA receptor antagonist: Interactive effects.                                                               (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813317/?tool=pubmed


Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines. (full – 2010)                                       http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930808/?tool=pubmed


cannabinoid receptors.                  (full – 2010)



Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation    (full – 2010)  http://www.nature.com/npp/journal/vaop/ncurrent/full/npp2010214a.html


Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects.                                                                 (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003779/


The Neuroprotective Effect of Cannabinoid Receptor Agonist (WIN55,212-2) in Paraoxon Induced Neurotoxicity in PC12 Cells and N-methyl-D-aspartate Receptor Interaction        (full – 2010)  http://celljournal.org/library/upload/article/af_4334422Hashemi.pdf


Energetic Metabolism and Human Sperm Motility: Impact of CB1 Receptor Activation (full – 2010)                                    http://endo.endojournals.org/content/151/12/5882.full


Perspectives of CB1 Antagonist in Treatment of Obesity: Experience of RIO-Asia (full – 2010)                                   http://www.hindawi.com/journals/jobes/2011/957268/


Characterization of the Endocannabinoid System in Human Spermatozoa and Involvement of Transient Receptor Potential Vanilloid 1 Receptor in Their Fertilizing Ability    (full – 2010)



Type 1 Cannabinoid Receptor-Containing Axons Innervate Hypophysiotropic Thyrotropin-Releasing Hormone-Synthesizing Neurons                                                                       (full – 2010)  http://endo.endojournals.org/content/150/1/98.full?sid=f5b14012-9fbe-4f10-890c-386313060cf8


Mechanisms of Broad-Spectrum Antiemetic Efficacy of Cannabinoids against Chemotherapy-Induced Acute and Delayed Vomiting                                                                      (link to PDF – 2010)  http://www.mdpi.com/1424-8247/3/9/2930


Endocannabinoids and Human Sperm Cells              (link to PDF – 2010)



Endocannabinoids and Schizophrenia             (link to PDF – 2010)



A model of endocannabinoid 2-AG-mediated depolarization-induced suppression of inhibition  (article – 2010)                               http://www.biomedcentral.com/1471-2202/11/S1/P189


Genes differentially expressed in CB1 knockout mice: involvement in the depressive-like phenotype.      (abst – 2010)                      http://www.ncbi.nlm.nih.gov/pubmed/20692131


cannabinoid receptors                 (abst – 2010)



Pharmacological exploitation of the endocannabinoid system: new perspectives for the treatment of depression and anxiety disorders?                                                                (abst – 2010)  http://www.unboundmedicine.com/medline/ebm/record/20512266/abstract/%5BPharmacological_exploitat ion_of_the_endocannabinoid_system:_new_perspectives_for_the_treatment_of_depression_and_anxiety_d isorders%5D_


Functionally selective cannabinoid receptor signalling: Therapeutic implications and opportunities  (abst – 2010)                                                         http://www.sciencedirect.com/science/article/pii/S0006295210001553


PP-014 Control of receptor expression in vagal afferent neurons by activation of cannabinoid 1 receptors                                                      (abst – 2010)  http://gut.bmj.com/cgi/content/meeting_abstract/59/1_MeetingAbstracts/A45-a?sid=0731f0e5-2071-4549-  be57-57f444307138


Expression of cannabinoid receptors in human kidney.                (abst – 2010)



Abnormal sensitivity of cannabinoid CB1 receptors in the striatum of mice with experimental amyotrophic lateral sclerosis.                                                                      (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/19452308


Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson’s disease in the rat.                                                           (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/20097273


Delta9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus.                                          (abst – 2010)  http://www.unboundmedicine.com/medline/ebm/record/20417220/abstract/Delta9_tetrahydrocannabinol_is



Regulation of nausea and vomiting by cannabinoids                (abst – 2010)  http://onlinelibrary.wiley.com/doi/10.1111/j.1476-  5381.2010.01176.x/abstract;jsessionid=56CED9CE51B025C161AA2E821BEC94ED.d01t01


A common variation in the cannabinoid 1 receptor (CNR1) gene is associated with pre- eclampsia in the Central European population.                                                         (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/21129839


G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population.                                                        (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/20851297


Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/19931541










Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity.                                                              (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/19147270


Expression of cannabinoid receptor I during mice skin incised wound healing course (abst – 2010)                                     http://www.ncbi.nlm.nih.gov/pubmed/20967946


Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans.         (abst – 2010)                            http://www.ncbi.nlm.nih.gov/pubmed/20618415


CB1 receptor deficiency decreases wheel-running activity: consequences on emotional behaviours and hippocampal neurogenesis.                                                                (abst – 2010)  http://www.ncbi.nlm.nih.gov/pubmed/20138171


Bimodal control of stimulated food intake by the endocannabinoid system. (abst – 2010)                                         http://www.ncbi.nlm.nih.gov/pubmed/20139974


Endocannabinoid (EC) Receptor, CB1, and EC Enzymes’ Expression in Primary Adipocyte Cultures of Lean and Obese Pre-pubertal Children in Relation to Adiponectin and Insulin           (abst – 2010)

http://www.degruyter.com/abstract/j/jpem.2010.23.issue-  10/jpem.2010.162/jpem.2010.162.xml?rskey=38kdx0&result=22&q=cannabinoid


Study shows direct cellular interaction between endocannabinoids and alcohol in the brain           (news – 2010)

http://www.news-medical.net/news/20100513/Study-shows-direct-cellular-interaction-between-  endocannabinoids-and-alcohol-in-the-brain.aspx


Cannabidiol (CBD) as an Anti-Arrhythmic – the Role of the CB1 Receptors (news – 2010)



Increasing the body’s (but not brain’s) cannabinoids dulls pain                 (news – 2010)



Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis                                                           (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025486/?tool=pubmed


Increased Expression of Cannabinoid CB(1) Receptors in Achilles Tendinosis. (full – 2011)                                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169627/?tool=pubmed


WIN55,212-2 induces cytoplasmic vacuolation in apoptosis-resistant MCL cells. (full – 2011)                                    http://www.nature.com/cddis/journal/v2/n11/full/cddis2011106a.html


Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents.                                                    (full – 2011)











Cannabinoid CB1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4                                                                   (full – 2011)  http://dmd.aspetjournals.org/content/early/2011/04/21/dmd.110.037812.full.pdf+html?maxtoshow=&hits=8   0&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcet  ype=HWCIT


Anandamide inhibits Theiler’s virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1 receptors.    (full – 2011)



Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging              (full– 2011)



Endocannabinoid system in cardiovascular disorders – new pharmacotherapeutic opportunities    (full – 2011)

http://www.jpbsonline.org/article.asp?issn=0975-  7406;year=2011;volume=3;issue=3;spage=350;epage=360;aulast=Cunha


Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces.    (full – 2011)                        http://www.molecularautism.com/content/pdf/2040-2392-2-10.pdf


Gadolinium-HU-308-incorporated micelles.                  (full – 2011)



Differential signaling in human cannabinoid CB(1) receptors and their splice variants in autaptic hippocampal neurons                                                        (full – 2011)  http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01744.x/pdf


A Pilot Study into the Effects of the CB1 Cannabinoid Receptor Agonist WIN55,212-2 or the Antagonist/Inverse Agonist AM251 on Sleep in Rats                                                     (full – 2011)  http://www.hindawi.com/journals/sd/2011/178469/


Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol. (full – 2011)                                     http://onlinelibrary.wiley.com/doi/10.1002/biof.131/full


Cannabinoid and GABA modulation of sympathetic nerve activity and blood pressure in the dorsal periaqueductal gray of the rat                                                        (full – 2011)  http://ajpregu.physiology.org/content/301/6/R1765.full


Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease.   (full – 2011)                          http://brain.oxfordjournals.org/content/134/1/119.long


Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor                                                             (full – 2011)  http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2010.07041.x/full









Cannabinoid exposure during zebra finch sensorimotor vocal learning persistently alters expression of endocannabinoid signaling elements and acute agonist responsiveness (full – 2011)                                  http://www.biomedcentral.com/1471-2202/12/3


Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise       (full – 2011)                             http://www.lipidworld.com/content/10/1/194


Comparison of Cannabinoid CB1 Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [18F]MK-9470  (full – 2011)  http://www.hindawi.com/journals/ijmi/2011/548123/


The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction

(link to PDF – 2011)               http://www.mdpi.com/1424-8247/4/8/1101


The role of the cannabinoid system in the pathogenesis and treatment of alcohol dependence       (link to PDF – 2011)  http://www.doaj.org/doaj?func=abstract&id=825351&q1=cannabinoid&f1=all&b1=and&q2=&f2=all&rec No=22&uiLanguage=en


Deficiency of Dietary Omega-3 May Explain Depressive Behaviors              (summary – 2011)  http://www.thefreelibrary.com/Deficiency+of+Dietary+Omega-3+May+Explain+Depressive+Behaviors.-  a0248155576


Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection.                                                          (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21873455


Possible involvement of the endocannabinoid system in memory modulation effect of general anesthetics                                               (abst  – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21555187/abstract/Possible_involvement_of_the_e   ndocannabinoid_system_in_memory_modulation_effect_of_general_anesthetics_


Genetic and pharmacological inactivation of cannabinoid CB1 receptor inhibits angiogenesis.      (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21460248/abstract/Genetic_and_pharmacological_  inactivation_of_cannabinoid_CB1_receptor_inhibits_angiogenesis_


Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice.                                                        (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/21785110


Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors.                (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/22116907/abstract/17_Cannabidiol_as_an_anti_arr  hythmic_the_role_of_the_CB1_receptors_


Regional changes in type 1 cannabinoid receptor availability in Parkinson’s disease in vivo           (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21459482/abstract/Regional_changes_in_type_1_c  annabinoid_receptor_availability_in_Parkinson%27s_disease_in_vivo_










Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation.                                                        (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22079984


Effects of cannabinoid CB(1) receptor agonism and antagonism on SKF81297-induced dyskinesia and haloperidol-induced dystonia in Cebus apella monkeys.                                                          (abst – 2011)   http://www.ncbi.nlm.nih.gov/pubmed/21029743


Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice.   (abst – 2011)                              http://www.ncbi.nlm.nih.gov/pubmed/20724033


The G protein-coupled cannabinoid-1 (CB(1)) receptor of mammalian brain: Inhibition by phthalate esters in vitro.                                                           (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/21763743


Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats.                                                         (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/21145311


Alkamides and a neolignan from Echinacea purpurea roots and the interaction of alkamides with G-protein-coupled cannabinoid receptors.                                                                       (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21764086


Brain Type 1 Cannabinoid Receptor Availability in Patients with Anorexia and Bulimia Nervosa.            (abst – 2011)                       http://www.ncbi.nlm.nih.gov/pubmed/21718968


Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors                                                     (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/20817042/abstract/Increment_of_hypothalamic_2_  arachidonoylglycerol_induces_the_preference_for_a_high_fat_diet_via_activation_of_cannabinoid_1_rece  ptors_


Type I cannabinoid receptor trafficking: all roads lead to lysosome.              (abst – 2011)



Intact cannabinoid CB1 receptors in the Alzheimer’s disease cortex.              (abst – 2011)



Indirect Sympatholytic Actions at β-Adrenoceptors Account for the Ocular Hypotensive Actions of Cannabinoid Receptor Agonists                                                        (abst – 2011)  http://jpet.aspetjournals.org/content/339/3/757.abstract?sid=2ef42c80-59ad-4b4e-8eed-d5b9d556b866


Endocannabinoid CB1 receptors modulate visual output from the thalamus. (abst – 2011)                                         http://www.ncbi.nlm.nih.gov/pubmed/21773721


Cannabinoids and emotionality: a neuroanatomical perspective.                 (abst – 2011)










The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors.        (abst – 2011)                                                      http://www.ncbi.nlm.nih.gov/pubmed/21887137


Bioactivation Pathways of the Cannabinoid Receptor 1 Antagonist Rimonabant (abst – 2011)



Loss of striatal cannabinoid CB1 receptor function in attention-deficit/hyperactivity disorder mice with point-mutation of the dopamine transporter.                                                         (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22034972


Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain.                                                        (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21813113


α-Tocopherol and α-tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus.                                                 (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/21843633


Interictal Type 1 Cannabinoid Receptor Binding is Increased in Female Migraine Patients.           (abst – 2011)                           http://www.ncbi.nlm.nih.gov/pubmed/22077199


Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET.                                                   (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/18077184


In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis.        (abst – 2011)                                         http://www.ncbi.nlm.nih.gov/pubmed/21303859


The endocannabinoid system in the cancer therapy: an overview.             (abst – 2011)



Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect.                                                       (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21298280


Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts (abst – 2011)                                     http://www.ncbi.nlm.nih.gov/pubmed/21575494



http://ajpgi.physiology.org/content/early/2011/11/28/ajpgi.00158.2011.abstract?sid=d420a7ad       -54ba-4946-  b1da-8bfe664eeec2


Impaired hippocampal glucoregulation in the cannabinoid CB(1) receptor knockout mice as revealed by an optimized in vitro experimental approach.                                               (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22155442










Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects.                                                             (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/22007164/abstract/Endocannabinoid_system_and_ psychiatry:_in_search_of_a_neurobiological_basis_for_detrimental_and_potential_therapeutic_effects_


Sexually dimorphic effects of cannabinoid compounds on emotion and cognition. (abst – 2011)




Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat

(abst – 2011)



The Effect of Hypoxia on G Protein Coupled (CB1) Receptor Gene Expression in Cortical B50 Neurons in Culture                                                                    (abst – 2011)  http://www.maxwellsci.com/jp/abstract.php?jid=BJPT&no=92&abs=05


CB1 receptors mediate rimonabant-induced pruritic responses in mice: investigation of locus of action.   (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21340468/abstract/CB1_receptors_mediate_rimon abant_induced_pruritic_responses_in_mice:_investigation_of_locus_of_action_


The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail. (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21244428/abstract/The_cannabinoid_type_1_recep tor_carboxyl_terminus_more_than_just_a_tail_


Chronic Δ⁹-tetrahydrocannabinol treatment in rhesus monkeys: differential tolerance and

cross-tolerance among cannabinoids.          (abst – 2011)

http://www.unboundmedicine.com/medline/ebm/record/21091643/abstract/Chronic_%CE%94%E2%81%B 9_tetrahydrocannabinol_treatment_in_rhesus_monkeys:_differential_tolerance_and_cross_tolerance_amon g_cannabinoids_


CB1 cannabinoid receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes. (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22211674


Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in bombesin- induced activation of central adrenomedullary outflow in rats.                                                             (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21371452


Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. (abst – 2011)











Intracellular Cannabinoid Type 1 (CB1) Receptors Are Activated by Anandamide (abst – 2011)



Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro (abst – 2011)                                      http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2011.01519.x/abstract


Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington’s disease.                                                          (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22207189


Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 Receptor. (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22044209


The genetic basis of the endocannabinoid system and drug addiction in humans (abst – 2011)                                       http://jop.sagepub.com/content/early/2011/09/20/0269881111416689


G1359A polymorphism in the cannabinoid receptor-1 gene is associated with coronary artery disease in the Chinese Han population.                                                                 (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/22029183


Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia.                                                 (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21420833


Effects of Chronic Oral Rimonabant Administration on Energy Budgets of Diet-Induced Obese C57BL/6 Mice.                                                   (abst – 2011)       http://www.ncbi.nlm.nih.gov/pubmed/22173576


Cannabinomimetic lipid from a marine cyanobacterium.                (abst – 2011)



Cannabinoid-1 Receptor Protects The Brain From Aging                (news – 2011)



Part of placebo effect ascribed to cannabinoids               (news – 2011)



What An Expectant Mother Eats Affects Children’s Psychology in Later Life (news – 2011)



The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription (full – 2012)                                      http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02175.x/full


Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver                                                          (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076854/?tool=pubmed










Synaptic Targets of Δ9-Tetrahydrocannabinol in the Central Nervous System. (full – 2012)  http://perspectivesinmedicine.cshlp.org/content/early/2012/12/03/cshperspect.a012237.long


Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption.                                                            (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004984/?tool=pubmed


Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain         (full – 2012)                                                      http://jpet.aspetjournals.org/content/338/1/114.full


Cannabinoids and atherosclerotic coronary heart disease.              (full – 2012)



Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells                                                          (full – 2012)  http://endo.endojournals.org/content/153/1/29.full


Excess of the endocannabinoid anandamide during lactation induces overweight, fat accumulation and insulin resistance in adult mice                                                          (full – 2012)  http://www.dmsjournal.com/content/4/1/35


Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors.                                                                   (full – 2012)  http://www.jbc.org/content/early/2012/07/11/jbc.M112.346296.full.pdf+html


Allosteric modulator ORG27569 induces a CB1 Cannabinoid receptor high affinity agonist binding state, receptor internalization and Gi-independent ERK1/2 activation. (full – 2012)                                  http://www.jbc.org/content/early/2012/02/16/jbc.M111.316463.long


Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST.                                                        (full – 2012)  http://www.sciencedirect.com/science/article/pii/S0028390812000470


Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function.                                                   (full – 2012)  http://www.nutritionandmetabolism.com/content/pdf/1743-7075-8-93.pdf


Cannabinoids Facilitate the Swallowing Reflex Elicited by the Superior Laryngeal Nerve Stimulation in Rats     (full – 2012)                                http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507745/


Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity. (full – 2012)                                       http://www.ncbi.nlm.nih.gov/pubmed/22829723?dopt=Abstract









Cannabinoid Receptor 1 (CNR1) 4895 C/T Genetic Polymorphism was Associated with Obesity in Japanese Men.                                                             (full – 2012)  https://www.jstage.jst.go.jp/article/jat/19/8/19_12732/_pdf


A polymorphism in the gene of the endocannabinoid-degrading enzyme FAAH (FAAH C385A) is associated with emotional–motivational reactivity                                                         (full – 2012)  http://link.springer.com/article/10.1007/s00213-012-2785-y/fulltext.html


Autocrine Endocannabinoid Signaling Through CB1 Receptors Potentiates OX1 Orexin Receptor Signaling.     (full – 2012)  http://molpharm.aspetjournals.org/content/early/2012/12/11/mol.112.080523.long


To Be or Not To Be—Obese                 (full – 2012)



Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant (full – 2012)                                http://www.nutritionj.com/content/11/1/50


The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription

(full – 2012)                  http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02175.x/abstract


Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging (full – 2012)                                      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131310/?tool=pubmed


Loss of CB1 receptors leads to differential age-related changes in reward-driven learning and memory.  (full – 2012)                           http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514639/


A Role for the Cannabinoid 1 Receptor in Neuronal Differentiation of Adult Spinal Cord Progenitors in vitro is Revealed through Pharmacological Inhibition and Genetic Deletion.          (full – 2012)                           http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265030/?tool=pubmed


Endocannabinoids Stimulate Human Melanogenesis via Type-1 Cannabinoid Receptor (full – 2012)                                      http://www.jbc.org/content/early/2012/03/19/jbc.M111.314880.full.pdf+html


Contribution of Hypothermia and CB(1) Receptor Activation to Protective Effects of TAK-937, a Cannabinoid Receptor Agonist, in Rat Transient MCAO Model.

(full– 2012)                http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397930/?tool=pubmed


Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. (full – 2012)                                        http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366638/


Type-1 Cannabinoid Receptor Signaling in Neuronal Development.              (full – 2012)



Differences in Spontaneously Avoiding or Approaching Mice Reflect Differences in CB1-Mediated Signaling of Dorsal Striatal Transmission.                                                             (full – 2012)











Neonatal DSP-4 Treatment Modifies Antinociceptive Effects of the CB(1) Receptor Agonist Methanandamide in Adult Rats.                                                              (full – 2012)  http://www.springerlink.com/content/d44543844w814p33/fulltext.html


Early Endogenous Activation of CB1 and CB2 Receptors after Spinal Cord Injury Is a Protective Response Involved in Spontaneous Recovery                                                (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496738/


Role of cannabinoids in the regulation of bone remodeling                  (full – 2012)



The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.                                                                                    (full – 2012)  http://www.jbc.org/content/early/2012/11/16/jbc.M112.364109.long


Cannabinoid modulation of neuroinflammatory disorders.             (full – 2012)



Small-animal PET imaging of the type 1 and type 2 cannabinoid receptors in a photothrombotic stroke model     (full – 2012)  http://link.springer.com/article/10.1007/s00259-012-2209-6/fulltext.html


Diet-dependent modulation of hippocampal expression of endocannabinoid signaling- related proteins in cannabinoid antagonist-treated obese rats.                                                (full – 2012)  http://onlinelibrary.wiley.com/doi/10.1111/ejn.12012/full


Therapeutic Potentials and uses of Cannabinoid Agonists in Health and Disease Conditions         (full – 2012)                                    http://maxwellsci.com/print/bjpt/v3-76-88.pdf


A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord   (full – 2012)  http://onlinelibrary.wiley.com/doi/10.1002/cne.23184/full


The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation (full – 2012)                                    http://www.jneuroinflammation.com/content/9/1/79


Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb.                                                (full– 2012)       http://www.jneurosci.org/content/32/25/8475.long


Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat        (full – 2012)










Neural Circuit in the Dorsal Raphe Nucleus Responsible for Cannabinoid-Mediated Increases in 5-HT Efflux in the Nucleus Accumbens of the Rat Brain

(link to PDF – 2012)                     http://www.hindawi.com/isrn/pharmacology/2012/276902/


Critical role of the endocannabinoid system in mediating rapid glucocorticoid effects on memory for emotionally arousing experiences                                                        (link to PDF – 2012)  http://www.doaj.org/doaj?func=abstract&id=1152481&q1=cannabinoid&f1=all&b1=and&q2=&f2=all&re cNo=3&uiLanguage=en


Endocannabinoids in stressed humans                (link to PDF – 2012)  http://www.doaj.org/doaj?func=abstract&id=1152482&q1=cannabinoid&f1=all&b1=and&q2=&f2=all&re cNo=2&uiLanguage=en


Positron emission tomography offers new perspectives for evidence-based treatment development in PTSD                                                     (link to PDF – 2012)  http://www.doaj.org/doaj?func=abstract&id=1152483&q1=endocannabinoid&f1=all&b1=and&q2=&f2=al  l&recNo=2&uiLanguage=en


Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23108547


Dynamic changes to the endocannabinoid system in models of chronic pain (abst – 2012)                                  http://www.ncbi.nlm.nih.gov/pubmed/23108548


JWH-018 and JWH-073: {Delta}9-Tetrahydrocannabinol-Like Discriminative Stimulus Effects in Monkeys.                                                (abst – 2012)  http://www.unboundmedicine.com/medline/ebm/record/21965552/abstract/JWH_018_and_JWH_073:_%7 BDelta%7D9_Tetrahydrocannabinol_Like_Discriminative_Stimulus_Effects_in_Monkeys_


The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain. (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22093909


Review article: Why do cannabinoid receptors have more than one endogenous ligand? (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/23108541


Review article: The endocannabinoid system in normal and pathological brain ageing (abst – 2012)



Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density.   (abst – 2012)                                                                 http://www.ncbi.nlm.nih.gov/pubmed/22005165


Contrasting effects of different cannabinoid receptor ligands on mouse ingestive behavior (abst – 2012)  http://www.unboundmedicine.com/medline/ebm/record/22772336/abstract/Contrasting_effects_of_differen  t_cannabinoid_receptor_ligands_on_mouse_ingestive_behaviour_









Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/23207972


Opposing Roles for Cannabinoid Receptor Type-1 (CB(1)) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats.      (abst – 2012)                                            http://www.ncbi.nlm.nih.gov/pubmed/21937980


Extinction learning of rewards in the rat: is there a role for CB1 receptors? (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/21519986


Tolerance to cannabinoid-induced behaviors in mice treated chronically with ethanol. (abst – 2012)                                       http://www.ncbi.nlm.nih.gov/pubmed/21701813


The cannabinoid receptor CB₁ inverse agonist AM251 potentiates the anxiogenic activity

of urocortin I in the basolateral amygdala.               (abst – 2012)



Cannabinoids and muscular pain. Effectiveness of the local administration in rat. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22354705


Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB(1) receptor-mediated anti-inflammatory effects. (abst – 2012)   http://www.ncbi.nlm.nih.gov/pubmed/22342378


The CB(1) Receptor-Mediated Endocannabinoid Signaling and NGF: The Novel Targets of Curcumin.  (abst – 2012)                          http://www.ncbi.nlm.nih.gov/pubmed/22311129


Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model.                                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22289684


Localization of mGluR5, GABA(B) , GABA(A) , and cannabinoid receptors on the vago- vagal reflex pathway responsible for transient lower esophageal sphincter relaxation in humans: an immunohistochemical study.                                                                                 (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22256945


Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor.      (abst – 2012)                             http://www.ncbi.nlm.nih.gov/pubmed/22248639


Endocannabinoids limit excessive mast cell maturation and activation in human skin. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22226549


Cannabinoid CB(1) receptor mediates glucocorticoid effects on hormone secretion induced by volume and osmotic changes.                                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22211674


[(125)I]SD-7015 reveals fine modalities of CB(1) cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer’s disease.                                                       (abst – 2012)











CB1 Agonist ACEA Protects Neurons and Reduces the Cognitive Impairment of AβPP/PS1 Mice.         (abst – 2012)                                http://www.ncbi.nlm.nih.gov/pubmed/22451318


CB1 cannabinoid receptor activation rescues amyloid β-induced alterations in behaviour and intrinsic electrophysiological properties of rat hippocampal CA1 pyramidal neurones. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22508047


Cortical basket cell dysfunction in schizophrenia.                (abst – 2012)



The cannabinoid agonist WIN55212-2 decreases l-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated rats.                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22192465


Cannabinergic Pain Medicine: A Concise Clinical Primer and Survey of Randomized- controlled Trial Results.                                                    (abst – 2012)        http://www.ncbi.nlm.nih.gov/pubmed/22367503


Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2.                                             (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22366523


Cannabinoid Receptor Genotype Moderation of the Effects of Childhood Physical Abuse on Anhedonia and Depression.                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22393204


Effect of delta-9-tetrahydrocannabinol on behavioral despair and on presynaptic and postsynaptic serotonergic transmission.                                                            (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22386778


Alteration of endocannabinoid system in human gliomas.                (abst – 2012)



Expression and localization of the cannabinoid receptor type 1 and the enzyme fatty acid amide hydrolase in the retina of vervet monkeys.                                                    (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22142900


Regulation of endocannabinoid release by G proteins: A paracrine mechanism of G protein-coupled receptor action.                                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22075205


Mitochondrial CB(1) receptors regulate neuronal energy metabolism.               (abst – 2012)



The Role of Cannabinoids In Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke.                                                                       (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22420307









Sex differences in cannabinoid receptor-1 (CB1) pharmacology in mice selectively bred for high voluntary wheel-running behavior.                                                         (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22405775


Effects of amphetamine on dopamine release in the rat nucleus accumbens shell region depend on cannabinoid CB1 receptor activation.                                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22426202


The decrease of dopamine D(2)/D(3) receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CB(1) cannabinoid receptors in Parkinson’s disease: A preliminary autoradiographic study with the selective dopamine D(2)/D(3) antagonist [(3)H]raclopride and the novel CB(1) inverse agonist [(125)I]SD7015.                                          (abst – 2012)        http://www.ncbi.nlm.nih.gov/pubmed/22421165


Cannabinoid receptors in submandibular acinar cells: functional coupling between saliva fluid and electrolytes secretion and Ca2+ signalling.                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22366450


Role of Lipid Rafts/Caveolae in the Anticancer Effect of Endocannabinoids. (abst – 2012)                                    http://www.ncbi.nlm.nih.gov/pubmed/22625418


On Disruption of Fear Memory by Reconsolidation Blockade: Evidence from Cannabidiol Treatment.     (abst – 2012)                                          http://www.ncbi.nlm.nih.gov/pubmed/22549120


Bimodal Control of Fear-Coping Strategies by CB1 Cannabinoid Receptors. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22623656


Revisiting CB1 Receptor as Drug Target in Human Melanoma.               (abst – 2012)



Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis.                                           (abst – 2012)         http://www.ncbi.nlm.nih.gov/pubmed/22738050


Stimulation of acumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats.                                           (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22728691


Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice. (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22778221


Lower levels of cannabinoid 1 receptor mRNA in female eating disorder patients: Association with wrist cutting as impulsive self-injurious behavior.                                                                       (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22542985


Cannabinoid modulation of midbrain urocortin 1 neurones during acute and chronic stress.          (abst – 2012)                       http://www.ncbi.nlm.nih.gov/pubmed/22734681









Anandamide Induces Matrix Metalloproteinase-2 Production through Cannabinoid-1 Receptor and Transient Receptor Potential Vanilloid-1 in Human Dental Pulp Cells in Culture.      (abst – 2012)                               http://www.ncbi.nlm.nih.gov/pubmed/22595113


Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo.                                                                 (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22579951


Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22553354


Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear. (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22534181


Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/22532560


Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain.

(abst – 2012)               http://www.ncbi.nlm.nih.gov/pubmed/22509801


Cannabinoid receptor 1 inhibition causes seizures during anesthesia induction in experimental sepsis.       (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/22504215


Tumor necrosis factor activation of vagal afferent terminal calcium is blocked by cannabinoids.   (abst – 2012)                                    http://www.ncbi.nlm.nih.gov/pubmed/22496569


A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors. (abst – 2012)                                    http://www.ncbi.nlm.nih.gov/pubmed/22404317


The cannabinoid CB1 receptor biphasically modulates motor activity and regulates dopamine and glutamate release region dependently.                                                                     (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22391102


Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD.                                                 (abst – 2012)        http://www.ncbi.nlm.nih.gov/pubmed/22385967


Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity.          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22266354


G1359A polymorphism in the cannabinoid receptor-1 gene is associated with the presence of coronary artery disease in patients with type 2 diabetes.                                                           (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22138970










Associations of variants of CNR1 with obesity and obesity-related traits in Chinese women.        (abst – 2012)                          http://www.ncbi.nlm.nih.gov/pubmed/22244745


Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets.                                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/21543209


The interaction between intrathecal administration of low doses of  palmitoylethanolamide and AM251 in formalin-induced pain related behavior and spinal cord IL1-β expression in rats.      (abst – 2012)                                                             http://www.ncbi.nlm.nih.gov/pubmed/22201038


CB(2) receptor and amyloid pathology in frontal cortex of Alzheimer’s disease patients. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/22763024


Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour.                                                       (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/11982628


Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome                                               (abst – 2012)  http://ajpgi.physiology.org/content/302/10/G1075.abstract?maxtoshow=&hits=25&RESULTFORMAT=&f  ulltext=cannabinoid&searchid=1&FIRSTINDEX=105&sortspec=date&resourcetype=HWCIT


In vivo type 1 cannabinoid receptor availability in Alzheimer’s disease                (abst – 2012)


&hits=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&  resourcetype=HWCIT


Cannabinoid Receptor Activity In The Tumour Necrosis Factor (tnf)−α-Induced Increased Contractility Of The Guinea-Pig Isolated Trachea                                                                 (abst – 2012)  http://ajrccm.atsjournals.org/cgi/reprint/185/1_MeetingAbstracts/A2154?maxtoshow=&hits=25&RESULT   FORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&resourcetype=HWCI  T



http://www.bjjprocs.boneandjoint.org.uk/content/94-  B/SUPP_XVIII/7.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=  1&FIRSTINDEX=130&sortspec=date&resourcetype=HWCIT


Cannabinoid receptors in submandibular acinar cells: Functional coupling between saliva fluid and electrolytes secretion and Ca2+ signalling                                                   (abst – 2012)  http://jcs.biologists.org/content/125/8/1884.abstract?maxtoshow=&hits=25&RESULTFORMAT=&fulltext



Photoperiodic Changes in Endocannabinoid Levels and Energetic Responses to Altered Signalling at CB1 Receptors in Siberian Hamsters                                               (abst – 2012)











2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism (abst – 2012)                                        http://www.sciencedirect.com/science/article/pii/S1550413112000526


Sex Differences in Cannabinoid 1 vs. Cannabinoid 2 Receptor-Selective Antagonism of Antinociception Produced by Δ9-Tetrahydrocannabinol and CP55,940 in the Rat

(abst – 2012)



Progesterone-dependent regulation of endometrial cannabinoid receptor type 1 (CB1-R) expression is disrupted in women with endometriosis and in isolated stromal cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).                                                                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22789143


Medial prefrontal cortex endocannabinoid system modulates baroreflex activity through CB1 receptors  (abst – 2012)  http://ajpregu.physiology.org/content/302/7/R876.abstract?sid=952e2125-0502-477c-b603-30f0f3e51b55


Non-Δ⁹tetrahydrocannabinol phytocannabinoids stimulate feeding in rats.

(abst – 2012)                     http://www.ncbi.nlm.nih.gov/pubmed/22157176


Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22836266


Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB(1) and CB(2) Receptors.        (abst – 2012)                               http://www.ncbi.nlm.nih.gov/pubmed/22860209


Cannabinoids inhibit peptidoglycan-induced phosphorylation of NF-κB and cell growth in U87MG human malignant glioma cells.                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22842590


Biphasic Effects of Cannabinoids in Anxiety Responses: CB1 and GABA(B) Receptors in the Balance of GABAergic and Glutamatergic Neurotransmission.                                        (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22850737


Genetic variability in the endocannabinoid system and 12-week clinical response to citalopram treatment: the role of the CNR1, CNR2 and FAAH genes                                                                  (abst – 2012)  http://jop.sagepub.com/content/early/2012/07/22/0269881112454229.abstract?maxtoshow=&hits=80&RES  ULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=H  WCIT


The CB(2)-preferring agonist JWH015 also potently and efficaciously activates CB(1) in autaptic hippocampal neurons.                                               (abst – 2012)     http://www.ncbi.nlm.nih.gov/pubmed/22921769


Brain regional differences in CB1 receptor adaptation and regulation of transcription.









(abst – 2012)               http://www.ncbi.nlm.nih.gov/pubmed/22940268


Modulation of sweet responses of taste receptor cells.               (abst – 2012)



The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity.                                             (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22943701


The FAAH inhibitor URB597 efficiently reduces tyrosine hydroxylase expression through CB(1) and FAAH-independent mechanisms.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22970888


Probing the Interaction of SR141716A with the CB1 Receptor.             (abst – 2012)



Cannabinoid CB(1) receptor in the modulation of stress coping behaviour in mice: the role of serotonin and different forebrain neuronal subpopulations.                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23000076


Opposing local effects of endocannabinoids on the activity of noradrenergic neurons and release of noradrenaline: relevance for their role in depression and in the actions of CB(1) receptor antagonists.      (abst – 2012)                                               http://www.ncbi.nlm.nih.gov/pubmed/22990678


The therapeutic potential of cannabis and cannabinoids.              (abst – 2012)



Failure to extinguish fear and genetic variability in the human cannabinoid receptor 1. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/23010766


Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice (abst – 2012)



Childhood Obesity and the Role of Dopamine D2 Receptor and Cannabinoid Receptor-1 Gene Polymorphisms.                                                   (abst – 2012)         http://www.ncbi.nlm.nih.gov/pubmed/23057570


Distribution and function of the endocannabinoid system in the rat and human bladder. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/23081739


Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice.               (abst – 2012)



Chronic activation of cannabinoid receptors in vitro does not compromise mouse islet function.   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23078523


Differences in the endocannabinoid system of sperm from fertile and infertile men. (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23082196










Cannabinoid Receptor Subtypes 1 and 2 Mediate Long-Lasting Neuroprotection and Improve Motor Behaviour Deficits After Transient Focal Cerebral Ischemia.

(abst – 2012)               http://www.ncbi.nlm.nih.gov/pubmed/23069763


Receptor-dependent and Receptor-independent Endocannabinoid Signaling: A Therapeutic Target for Regulation of Cancer Growth.                                                                       (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23069587


△9-Tetrahydrocannabinol Impairs the Inflammatory Response to Influenza Infection:

Role of Antigen Presenting Cells and the Cannabinoid Receptors 1 and 2.            (abst – 2012)



The Volitional Nature of Nicotine Exposure Alters Anandamide and Oleoylethanolamide Levels in the Ventral Tegmental Area.                                                      (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23169348


Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington’s disease and mouse models.                                                         (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23167744


The CB1 Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis.                                                      (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23175820


Cannabinoid Modulation of Midbrain Urocortin 1 Neurones During Acute and Chronic Stress    (abst – 2012)



CB1 receptor activation in the nucleus accumbens core impairs contextual fear learning. (abst – 2012)                                    http://www.ncbi.nlm.nih.gov/pubmed/23018128


Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate.                                                       (abst – 2012)        http://www.ncbi.nlm.nih.gov/pubmed/23199705


Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23142606?dopt=Abstract


Marine Cyanobacterial Fatty Acid Amides Acting on Cannabinoid Receptors. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/23143757?dopt=Abstract


Cannabinoid type 1 receptor ligands WIN 55,212-2 and AM 251 alter anxiety-like behaviors of marmoset monkeys in an open-field test.                                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23183218









Cannabinoid Receptor Antagonist-Induced Striated Muscle Toxicity and Ethylmalonic- Adipic Aciduria in Beagle Dogs                                                             (abst – 2012)  http://toxsci.oxfordjournals.org/content/129/2/268.short?rss=1


Cannabinoid receptor expression at the MNTB-LSO synapse in developing rats. (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22230885


Functional diversity on synaptic plasticity mediated by endocannabinoids (abst – 2012)                                  http://www.ncbi.nlm.nih.gov/pubmed/23108543


WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal cerebral ischemia in rats.                                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23202804


Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy.                                                                (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23206503


Binding of a tritiated inverse agonist to cannabinoid CB1 receptors is increased in patients with schizophrenia                                                        (abst – 2012)      http://www.ncbi.nlm.nih.gov/pubmed/22910406


Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis (abst – 2012)                                        http://www.ncbi.nlm.nih.gov/pubmed/22669247


Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes.                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22701012?dopt=Abstract


The FAAH inhibitor URB597 efficiently reduces tyrosine hydroxylase expression through CB1 and FAAH-independent mechanisms                                                         (abst – 2012)  http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02208.x/abstract


The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity                                               (abst – 2012)  http://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2012.01026.x/abstract


TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts.                                               (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22656960?dopt=Abstract


Anandamide Induces Matrix Metalloproteinase-2 Production through Cannabinoid-1 Receptor and Transient Receptor Potential Vanilloid-1 in Human Dental Pulp Cells in Culture       (abst – 2012)                       http://www.jendodon.com/article/PIIS0099239912002191/abstract?rss=yes


Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice.                                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/21883147









Tumour epithelial expression levels of endocannabinoid markers modulates the value of endoglin-positive vascular density as a prognostic marker in prostate cancer.

(abst – 2012)                http://www.ncbi.nlm.nih.gov/pubmed/23262399


Revisiting CB1 receptor as drug target in human melanoma.                (abst – 2012)



Age of Stress Exposure Modulates the Immediate and Sustained Effects of Repeated Stress on. (abst – 2012)                               http://www.ncbi.nlm.nih.gov/pubmed/23200786


Cannabinoid receptors: nomenclature and pharmacological principles.              (abst – 2012)



Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake. (abst – 2012)                                     http://www.ncbi.nlm.nih.gov/pubmed/23207972


Ventral Tegmental Area Cannabinoid Type-1 Receptors Control Voluntary Exercise Performance.          (abst – 2012)                          http://www.ncbi.nlm.nih.gov/pubmed/23237313


WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination.                                                                                      (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23202804


Discovery of agonists of cannabinoid receptor 1 with restricted CNS penetration aimed for treatment of gastroesophageal reflux disease.                                          (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23227781


The effects of fasting duration on gastric emptying in man, an exploration of the role of the endocannabinoid system and inter-individual responsiveness                                                   (abst – 2012)  http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2012.01954.x/abstract


The Contractile Effect of Anandamide in the Guinea-Pig Small Intestine is Mediated by Prostanoids but not TRPV1 Receptors or Capsaicin-Sensitive Nerves. (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23216932


Update on the endocannabinoid-mediated regulation of gelatinase release in arterial wall physiology and atherosclerotic pathophysiology.                                         (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23253273


Positron Emission Tomography Shows Elevated Cannabinoid CB 1 Receptor Binding in Men with Alcohol Dependence                                             (abst – 2012)  http://onlinelibrary.wiley.com/doi/10.1111/j.1530-0277.2012.01815.x/abstract


Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice                                                           (abst – 2012)  http://eurheartj.oxfordjournals.org/content/33/24/3124.short?rss=1









Effects of gonadal hormones on the peripheral cannabinoid receptor 1 (CB1R) system under a myositis condition in rats.                                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22940464


Uncovering a role for endocannabinoid signaling in autophagy in preimplantation mouse embryos            (abst – 2012)                    http://molehr.oxfordjournals.org/content/19/2/93.abstract


Determination of naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in mouse blood and tissue after inhalation exposure to ‘buzz’ smoke by HPLC/MS/MS

(abst – 2012)               http://onlinelibrary.wiley.com/doi/10.1002/bmc.2710/abstract


Sensation-seeking genes and physical activity in youth                  (abst – 2012)



Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor.           (abst – 2013)                   http://www.ncbi.nlm.nih.gov/pubmed/23150578


Spinal Cord Fatty Acid Amide Hydrolase (FAAH) in Normal Micturition Control and Bladder Overactivity in Awake Rats.                                                             (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23219540


Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report (abst – 2012)                                       http://onlinelibrary.wiley.com/doi/10.1111/jcpt.12018/abstract


Mechanism of the Interaction of Cannabinoid System in Central Amygdale with Opioid System  (abst – 2012)                         http://journal.muq.ac.ir/en/index.php/jmuqen/article/view/29


Endocannabinoid system and mood disorders: Priming a target for new therapies. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/23261685


Cannabinoid Receptor Function is Altered by Nutrionally Deficient Diet            (news – 2012)  http://www.examiner.com/medical-marijuana-in-philadelphia/cannabinoid-receptor-function-is-altered-by-  nutrionally-deficient-diet


Structured Unlearning: Marijuana May Impair Memory via the Brain’s Non-Firing Cells (news – 2012)



Do deficits in brain cannabinoids contribute to eating disorders?              (news – 2012)



Developmental and Visual Input-Dependent Regulation of the CB1 Cannabinoid Receptor in the Mouse Visual Cortex.                                                               (full – 2013)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540079/


Role of endocannabinoids and cannabinoid-1 receptors in cerebrocortical blood flow regulation. (full – 2013)                               http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537620/









Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations.                                                        (full – 2013)  http://onlinelibrary.wiley.com/doi/10.1002/pro.2192/full


THE ENDOCANNABINOID SYSTEM PROVIDES AN AVENUE FOR EVIDENCE- BASED TREATMENT DEVELOPMENT FOR PTSD                                                          (1st page – 2013)



Predator threat stress promotes long lasting anxiety-like behaviors and modulates synaptophysin and CB1 receptors expression in brain areas associated with PTSD symptoms.  (abst – 2013)   http://www.ncbi.nlm.nih.gov/pubmed/23178193


WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination.                                                                                     (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23148948


Cannabinoid Receptor 1 Gene and Irritable Bowel Syndrome: Phenotype and Quantitative Traits.           (abst – 2013)                                     http://www.ncbi.nlm.nih.gov/pubmed/23306084


CB1 and CB2 Cannabinoid Receptor Agonists Induce Peripheral Antinociception by Activation of the Endogenous Noradrenergic System.                                        (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23302980


The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23298518


The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects.                                         (abst – 2013)         http://www.ncbi.nlm.nih.gov/pubmed/23296873


Cannabinoid Receptors as Therapeutic Targets for Dialysis-Induced Peritoneal Fibrosis. (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23296044


LiCABEDS II. Modeling of Ligand Selectivity for G-protein Coupled Cannabinoid Receptors.   (abst – 2013)                              http://www.ncbi.nlm.nih.gov/pubmed/23278450


Surinabant, a selective CB(1) antagonist, inhibits THC-induced central nervous system and heart rate effects in humans.                                                       (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23278647


Striatal CB1 and D2 receptors regulate expression of each other, crip1a and delta opioid systems.           (abst – 2013)                 http://www.ncbi.nlm.nih.gov/pubmed/23286559


Neuron-type specific cannabinoid-mediated G protein signalling in mouse hippocampus. (abst – 2013)                                    http://www.ncbi.nlm.nih.gov/pubmed/23289830


Endocannabinoid/GABA interactions in the entopeduncular nucleus modulates alcohol intake in rats.     (abst – 2013)                          http://www.ncbi.nlm.nih.gov/pubmed/23291357










Effects of glucagon-like peptide-1 receptor stimulation and blockade on food consumption and body weight in rats treated with a cannabinoid CB1 receptor agonist WIN 55,212-2.   (abst – 2013)                                                      http://www.ncbi.nlm.nih.gov/pubmed/23291632


Evidence for the involvement of cannabinoid receptors’ polymorphisms in the pathophysiology of human diseases.                                                                          (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23293857


Behavioral Responses to Acute and Sub-chronic Administration of the Synthetic Cannabinoid JWH-018 in Adult Mice Prenatally Exposed to Corticosterone. (abst – 2013)   http://www.ncbi.nlm.nih.gov/pubmed/23296549


Cannabinoid CB(1) receptor is expressed in chromophobe renal cell carcinoma and renal oncocytoma.     (abst – 2013)                        http://www.ncbi.nlm.nih.gov/pubmed/23318578


Functional Residues Essential for the Activation of the CB1 Cannabinoid Receptor. (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23332708


DHA prevents altered 5-HT1(A), 5-HT2(A), CB1 and GABA(A) receptor binding densities in the brain of male rats fed a high-saturated-fat diet.                                                              (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23337348


Genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) and their influence on anthropometric parameters and metabolic parameters under a high monounsaturated vs. high polyunsaturated fat hypocaloric diets.                                                                                         (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23337343


Developmentally-induced hypothyroidism alters the expression of Egr-1 and Arc genes and the sensitivity to cannabinoid agonists in the hippocampus. Possible implications for memory and learning. (abst – 2013)                                                   http://www.ncbi.nlm.nih.gov/pubmed/23079472


Type-1 (CB(1)) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells.                                                                      (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23372698


Δ9-tetrahydrocannabinol impairs the inflammatory response to influenza infection: role of antigen-presenting cells and the cannabinoid receptors 1 and 2.                                                             (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23152191


Endocannabinoids and obesity.           (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23374723


The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis.                                                                (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23373571


Nicotine-Induced Neuroprotection Against Ischemic Injury Involves Activation of Endocannabinoid System in Rats                                                            (abst – 2013)  http://link.springer.com/article/10.1007/s11064-012-0927-6










Stimulatory and Inhibitory Roles of Brain 2-Arachidonoylglycerol in Bombesin-Induced Central Activation of Adrenomedullary Outflow in Rats.                                                           (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23386378


Rapid Glucocorticoid-Induced Activation of TRP and CB1 Receptors Causes Biphasic Modulation of Glutamate Release in Gastric-Related Hypothalamic Preautonomic Neurons.  (abst – 2013)                                    http://www.ncbi.nlm.nih.gov/pubmed/23386808


The pharmacologic and clinical effects of medical cannabis.                       (abst – 2013)



Neonatal lipopolysaccharide treatment has long term effects on monoaminergic and cannabinoid receptors in the rat.                                                                    (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23389966


Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle                                                          (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23396229


Role of cannabinoid and vanilloid receptors in invasion of human breast carcinoma cells (abst – 2013)                                             http://www.ncbi.nlm.nih.gov/pubmed/23394450


Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects.

(abst – 2013)                      http://www.ncbi.nlm.nih.gov/pubmed/23412396


Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding.                                                                                                        (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23408552


Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.                                                                          (abst – 2013)  http://link.springer.com/article/10.1007%2Fs00213-013-2995-y


Why resolutions about taking up physical activity are hard to keep.                       (news – 2013)  http://www.thefreelibrary.com/Why+resolutions+about+taking+up+physical+activity+are+hard+to+keep.       –   a0313904638


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