CBDA/CANNABIDIOLIC ACID – precursor to Cannabidiol


Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L.. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid.     (full – 1996)  http://www.jbc.org/content/271/29/17411.long


Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis. (full – 2008)                                         http://dmd.aspetjournals.org/content/36/9/1917.long

Phytocannabinoids for use in the treatment of cancer   – Patent GB2478595  (A) ― 2011-09-14            (full – 2011)




Cannabis as a Unique Functional Food   (full – 2011)



The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus.                                                             (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21975813/abstract/The_effects_of_cannabidiolic_a  cid_and_cannabidiol_on_contractility_of_the_gastrointestinal_tract_of_Suncus_murinus_


Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.                                                           (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21175579/abstract/Effects_of_cannabinoids_and_c   annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_


Cannabidiol May Fight Alzheimer’s Disease                        (news – 2011)



Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro.                                                                  (abst – 2012)     http://www.ncbi.nlm.nih.gov/pubmed/22233683


Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects.                                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22411724


Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA- MB-231 breast cancer cell migration.                                                                   (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22963825


Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR.                                                  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23280038


Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT(1A) receptor activation.                                                            (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23121618

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