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CANCER – COLON /COLORECTAL

CANCER – COLON /COLORECTAL

 

Possible endocannabinoid control of colorectal cancer growth.                         (abst – 2003)

Possible endocannabinoid control of colorectal can… [Gastroenterology. 2003] – PubMed result

 

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation.            (full – 2004)

Inflammation and Cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation

 

Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes.        (abst – 2004)

Agonists of cannabinoid receptor 1 and 2 inhibit e… [Am J Physiol Gastrointest Liver Physiol. 2006] –  PubMed result

 

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2                                                             (full – 2005)

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role  for cyclooxygenase 2

 

A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells         (full – 2005)

A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells

 

Cannabinoids and cancer: potential for colorectal cancer therapy.                  (abst – 2005)

Cannabinoids and cancer: potential for colorectal … [Biochem Soc Trans. 2005] – PubMed result

 

A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells. (full – 2006)                                    http://molpharm.aspetjournals.org/content/70/1/51.long

 

Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth : RECRUITMENT OF Fas AND Fas LIGAND TO LIPID RAFTS                                                                       (full – 2007)

http://www.jbc.org/content/282/17/13098.full

 

The cannabinoid CB(2) receptor: a good friend in the gut.               (abst – 2007)

http://www.ncbi.nlm.nih.gov/pubmed/17727390

 

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. (abst – 2007)   http://www.ncbi.nlm.nih.gov/pubmed/17583570

 

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.    (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755791/?tool=pubmed

 

Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha- mediated ceramide de novo synthesis in colon cancer cells.                                                          (full – 2008)  http://clincancerres.aacrjournals.org/content/14/23/7691.long

 

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects      (abst – 2008)                           http://gut.bmj.com/content/57/8/1140.abstract

 

Turned-Off Cannabinoid Receptor Turns On Colorectal Tumor Growth              (news – 2008)

http://www.sciencedaily.com/releases/2008/08/080801074056.htm

 

Marijuana takes on colon cancer                (news – 2008)

Marijuana takes on colon cancer – health – 01 August 2008 – New Scientist

 

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer         (news – 2008)                           http://www.news-medical.net/news/2008/08/03/40485.aspx

 

Induction of the antitumorigenic NSAID-activated gene (NAG-1) in synthetic hexahydrocannabinol-induced apoptosis of human colorectal cancer cells                                                                (abst – 2009)  http://www.fasebj.org/cgi/content/meeting_abstract/23/1_MeetingAbstracts/761.5?maxtoshow=&hits=80& RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HW  CIT

 

Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil.                                           (abst + 1st page – 2009)  http://www.springerlink.com/content/45008p9643k139l4/

 

Cannabinoids in intestinal inflammation and cancer                (abst – 2009)

http://www.ncbi.nlm.nih.gov/pubmed/19442536

 

US Patent Application 20100222437 – COMPOSITION CONTAINING NON- PSYCHOTROPIC CANNABINOIDS FOR THE TREATMENT OF INFLAMMATORY DISEASES        (full – 2010)

http://www.patentstorm.us/applications/20100222437/fulltext.html

 

The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells.                                                       (abst, link to PDF – 2010)  http://www.spandidos-publications.com/ijo/37/1/187

 

Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability.        (abst – 2010)                           http://www.ncbi.nlm.nih.gov/pubmed/20592049

 

Effects of anandamide on polyamine levels and cell growth in human colon cancer cells (abst – 2010)                                    http://www.ncbi.nlm.nih.gov/pubmed/20682986

 

Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells

(abst – 2010)                http://www.sciencedirect.com/science/article/pii/S0006295210001735

 

Involvement of NSAID-activated gene-1 in a novel synthetic hexahydrocannabinol analogue-induced growth inhibition and apoptosis of colon cancer cells                                                       (abst – 2010)  http://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/965.8?maxtoshow=&hits=80&   RESULTFORMAT=&fulltext=Hexahydrocannabinol&searchid=1&FIRSTINDEX=0&resourcetype=HW  CIT

 

Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full – 2011)  https://www.jstage.jst.go.jp/article/bpb/34/5/34_5_774/_pdf

 

Phytocannabinoids for use in the treatment of cancer   – Patent  GB2478595  (A) ― 2011-09-14            (full – 2011)

http://worldwide.espacenet.com/publicationDetails/biblio?CC=GB&NR=2478595A&KC=A&FT=D&ND=

&date=20110914&DB=&locale=en_EP

 

Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth.  (abst – 2011)                                   http://www.ncbi.nlm.nih.gov/pubmed/21412772

 

Anandamide inhibits the growth of colorectal cancer cells through CB1 and lipid rafts (abst – 2011)                                  http://www.ncbi.nlm.nih.gov/pubmed/21575494

 

Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.      (abst – 2011)                             http://www.ncbi.nlm.nih.gov/pubmed/22110202

 

Anti-tumor activity of the novel hexahydrocannabinol analog LYR-8 in Human colorectal tumor xenograft is mediated through the inhibition of Akt and hypoxia- inducible factor-1α activation.          (full – 2012)  https://www.jstage.jst.go.jp/article/bpb/35/6/35_b12-00020/_pdf

 

The atypical cannabinoid O-1602 shows antitumorigenic effects in colon cancer cells and reduces tumor growth in a colitis-associated colon cancer model                                                                    (full – 2012)  http://www.biomedcentral.com/content/pdf/2050-6511-13-S1-A23.pdf

 

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.                                                               (abst – 2012)       http://www.ncbi.nlm.nih.gov/pubmed/22231745

 

O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms.                                              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22965195

 

How Weed Can Protect Us From Cancer and Alzheimer’s                       (book excerpt – 2012)

http://www.alternet.org/story/156269/how_weed_can_protect_us_from_cancer_and_alzheimer%27s

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