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A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat.                                             (abst – 1993)


Development of HU-211 as a neuroprotectant for ischemic brain damage.                  (abst – 1995)


45Ca accumulation in rat brain after closed head injury; attenuation by the novel neuroprotective agent HU-211.                                                                     (abst – 1995)


Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant.                                                             (abst – 1997)


How hash became a smash in brain trauma research               (news – 1998)


Exogenous anandamide protects rat brain against acute neuronal injury in vivo. (full – 2001)                        


Brain Injury Circumvented by Endocannabinoids              (abst – 2001);2001/104/tw380?maxtoshow=&hits=80&RESULT   FORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=1680&resourcetype=HWCIT


An endogenous cannabinoid (2-AG) is neuroprotective after brain injury.             (abst – 2001)


Cannabinoids on the Brain             (full – 2002)


Cannabinoids and brain injury: therapeutic implications             (full – 2002)


Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trial.                                                              (abst – 2002)


Neuroprotective and brain edema-reducing efficacy of the novel cannabinoid receptor agonist BAY 38-7271.                                                   (abst – 2003)


BAY 38-7271: a novel highly selective and highly potent cannabinoid receptor agonist for the treatment of traumatic brain injury.                                                (abst – 2003)


Cannabinoids As Neuroprotective Agents in Traumatic Brain Injury.               (abst – 2004)


The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines.                                                           (abst – 2005)


The Cannabinoid CB2 Receptor as a Target for Inflammation-Dependent Neurodegeneration      (full – 2006)


The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines.                                                         (abst – 2006)


Anandamide, an endocannabinoid, protects neurons from inflammation after brain damage          (news – 2006)



The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis                                                              (full – 2007)


Endocannabinoids and traumatic brain injury.              (abst – 2007)


The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.       (full – 2008)                   


LSUHSC research reports new method to protect brain cells from diseases like Alzheimer’s         (news – 2008)


Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease

(full – 2009)             


Breakthrough in treatment of Traumatic Brain Injury: KeyNeurotek’s clinical study reaches primary endpoint and shows significant increase in survival                                                                 (news – 2009)  reaches-primary-endpoint-shows-8667.html


Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality.                                                            (full – 2010)


Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage.

(abst – 2011)        


N-arachidonoyl-L-serine is neuroprotective after traumatic brain injury by reducing apoptosis      (abst – 2011) europrotective_after_traumatic_brain_injury_by_reducing_apoptosis_


Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a murine model of traumatic brain injury                                                          (abst – 2011)





Acute effects of a selective cannabinoid-2 receptor agonist on neuroinflammation in a model of traumatic brain injury.                                                      (abst – 2011) annabinoid_2_receptor_agonist_on_neuroinflammation_in_a_murine_model_of_traumatic_brain_injury_


New metabolic pathway for controlling brain inflammation (news – 2011)  inflammation.aspx


Site-specific and time-dependent activation of the endocannabinoid system after transection of long-range projections.                                                                 (full – 2012)


Cannabis Responsive Head Injury Induced Mutiple Disabilities: A Case Report (link to PDF- 2012)                                          


Cannabidiol for neurodegenerative disorders: important new clinical applications for this hytocannabinoids?                                                       (abst – 2012)


Early Survival of Comatose Patients after Severe Traumatic Brain Injury with the Dual Cannabinoid CB1/CB2 Receptor Agonist KN38-7271: A Randomized, Double-Blind, Placebo-Controlled Phase II Trial.           (abst – 2012)


A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury.                                                                    (abst – 2012)


Type-1 (CB(1)) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells.                                                                            (abst – 2013)

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