ARTHRITIS

 

ANTI-EDEMA AND ANALGESIC PROPERTIES OF Δ9- TETRAHYDROCANNABINOL (THC)  (abst – 1973)

http://jpet.aspetjournals.org/content/186/3/646.abstract?maxtoshow=&hits=80&RESULTFORMAT=&fullt ext=marihuana&searchid=1&FIRSTINDEX=2160&resourcetype=HWCIT

 

Analgesic and antiinflammatory activity of constituents of Cannabis sativa L. (full – 1988)  http://www.ukcia.org/research/AnalgesicAndAntiInflammatoryActivityofConstituents.html

 

US Patent 6132762 – Transcutaneous application of marijuana                    (full – 2000)

http://www.patentstorm.us/patents/6132762/fulltext.html

 

Immunoactive cannabinoids: Therapeutic prospects for marijuana constituents

(full – 2000)                      http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=34030&tool=pmcentrez

 

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis                                                     (full – 2000)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC16904/?tool=pubmed

 

Marijuana Extract Helps Arthritis Pain                      (news – 2000)

http://www.prohealth.com//library/showArticle.cfm?libid=552

 

Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints (full – 2001)                                     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572613/?tool=pmcentrez

 

Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst – 2003)                                    http://www.ncbi.nlm.nih.gov/pubmed/14644587

 

Cannabis May Suppress Immune System                (news – 2003)

http://lupus.webmd.com/news/20030415/cannabis-may-suppress-immune-system

 

A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis.                                                 (full – 2004)  http://onlinelibrary.wiley.com/doi/10.1002/art.20050/full

 

Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (abst – 2005)                                    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751505/?tool=pmcentrez

 

Rheumatoid arthritis, Cannabis based medicine eases pain and suppresses disease (news – 2005)                                      http://www.medicalnewstoday.com/articles/33376.php

 

Cannabis-Based Drug Relieves Arthritis Pain               (news – 2005)

http://www.medpagetoday.com/Rheumatology/Arthritis/2097

 

First study to use a cannabis-based medicine for treating rheumatoid arthritis (news – 2005)         http://www.news-medical.net/news/2005/11/09/14393.aspx

 

Pot-Based Drug Promising for Arthritis                (news – 2005)

http://www.webmd.com/rheumatoid-arthritis/news/20051108/pot-based-drug-promising-for-arthritis

 

Cannabis-based medicine relieves the pain of rheumatoid arthritis and suppresses the disease       (news – 2005)                          http://www.eurekalert.org/pub_releases/2005-11/oup-cmr110705.php

 

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis                                                       (full – 2006)  http://rheumatology.oxfordjournals.org/cgi/content/full/45/1/50?maxtoshow=&hitqs=80&RESULTFORM  AT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=2240&resourcetype=HWCIT

 

The use of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis   (letter – 2006)  http://rheumatology.oxfordjournals.org/cgi/content/full/45/6/781

 

Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro.                                                     (abst – 2006)  http://www.ncbi.nlm.nih.gov/pubmed/16536902

 

The Cannabinergic System as a Target for Anti-inflammatory Therapies                (abst – 2006)

http://www.ingentaconnect.com/content/ben/ctmc/2006/00000006/00000013/art00008

 

In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219539/?tool=pmcentrez

 

Arthritis and pain. Future targets to control osteoarthritis pain.              (full – 2007)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2206352/?tool=pubmed

 

Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid.        (abst – 2007)                                  http://www.ncbi.nlm.nih.gov/pubmed/16927387

 

The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat involves the CB(2) cannabinoid receptor.                                              (abst – 2007)  http://www.unboundmedicine.com/medline/ebm/record/17588560/abstract/The_antinociceptive_effect_of_

 

 

 

 

Synergy between Delta(9)-tetrahydrocannabinol and morphine in the arthritic rat (abst – 2007) http://www.unboundmedicine.com/medline/ebm/record/17498686/abstract/Synergy_between_Delta_9 rahydrocannabinol_and_morphine_in_the_arthritic_rat


 

 

 

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Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis.                                                                   (full – 2008)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453762/?tool=pubmed

 

In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full – 2008)  http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2219539&tool=pmcentrez

 

Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. (full – 2008)                                      http://onlinelibrary.wiley.com/doi/10.1002/art.23156/full

 

CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways.                                                             (full – 2008)  http://ajpheart.physiology.org/content/294/3/H1145.long

 

Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid. (abst – 2008)                                   http://www.ncbi.nlm.nih.gov/sites/pubmed

 

Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells. (abst – 2008)  http://www.ncbi.nlm.nih.gov/pubmed/17786950

 

Anti-inflammatory compound from cannabis found in herbs                (news – 2008)

http://www.rsc.org/chemistryworld/News/2008/June/24060801.asp

 

Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4                                                                            (full – 2009)

 

http://www.fasebj.org/cgi/content/full/23/5/1503?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=c  annabis&searchid=1&FIRSTINDEX=2400&resourcetype=HWCIT

 

Cannabinoids as novel anti-inflammatory drugs.               (full – 2009)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/?tool=pubmed

 

How Hemp Seed Oil Can Help Your Arthritis                (news – 2009)

http://www.thefreelibrary.com/How+Hemp+Seed+Oil+Can+Help+Your+Arthritis-a01074002477

 

Medical Marijuana and Reiter’s Syndrome                (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/57?ailment=reiter-s-syndrome

 

Medical Marijuana and Arthritis               (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/72?ailment=arthritis

 

Medical Marijuana and Arthritis (Rheumatoid)                (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/105?ailment=arthritis-rheumatoid-

 

Medical Marijuana and Post-traumatic arthritis               (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/85?ailment=post-traumatic-arthritis

 

Medical Marijuana and Degenerative Arthritis               (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/83?ailment=degenerative-arthritis

 

Medical Marijuana and Degenerative Arthropathy              (news – 2009)

https://www.marijuanadoctors.com/content/ailments/view/126?ailment=degenerative-arthropathy

 

Tissue Engineering of Cartilage; Can Cannabinoids Help?              (full – 2010)

http://www.tara.tcd.ie/bitstream/2262/40674/1/Tissue%20Engineering%20of%20Cartilage%20-

%20Can%20Cannabinoids%20Help.pdf

 

Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full – 2010)                                    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005548/?tool=pubmed

 

Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain.                                                           (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132591/?tool=pubmed

 

Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis. (abst – 2010)

http://www.unboundmedicine.com/medline/ebm/record/21185649/abstract/Local_application_of_the_endo  cannabinoid_hydrolysis_inhibitor_URB597_reduces_nociception_in_spontaneous_and_chemically_induce   d_models_of_osteoarthritis_

 

Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain.                                                            (abst – 2010)     http://www.ncbi.nlm.nih.gov/pubmed/20863899

 

Plaquenil, Rheumatoid Arthritis, Lupus and Marijuana (Cannabis)              (news – 2010)

 

http://www.mcsocal.com/blog/plaquenil-rheumatoid-arthritis-lupus-and-marijuana-cannabis

 

Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011)                                  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/

 

Cannabinoids for Treatment of Chronic Non-Cancer Pain; a Systematic Review of Randomized Trials.   (abst – 2011)                                     http://www.ncbi.nlm.nih.gov/pubmed/21426373

 

Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.                                            (abst – 2011)              http://www.ncbi.nlm.nih.gov/pubmed/21238581

 

The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55.                                                      (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21683763

 

Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice.                                                               (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21740924

 

Echinacea & Arthritis                (news – 2011)

http://www.livestrong.com/article/369067-echinacea-arthritis/

 

Medical Reasons for Marijuana                 (news – 2011)

http://www.livestrong.com/article/98476-medical-reasons-marijuana/

 

Platelet-rich plasma loaded hydrogel scaffold enhances chondrogenic differentiation and maturation with up-regulation of CB1 and CB2.                                                (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22366523

 

Effects of Peptide and Lipid Endocannabinoids on Arthritic Pain at Spinal Level. (abst – 2012)                                      http://www.ncbi.nlm.nih.gov/pubmed/22451592

 

Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system.           (abst – 2012)                           http://www.ncbi.nlm.nih.gov/pubmed/22595021

 

Cannabinoids: novel therapies for arthritis?                  (abst – 2012)

http://www.ncbi.nlm.nih.gov/pubmed/22530636

 

 

 

 

Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid system                                                            (abst – 2012)  http://onlinelibrary.wiley.com/doi/10.1002/art.37684/abstract

 

Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate.                                                       (abst – 2012)        http://www.ncbi.nlm.nih.gov/pubmed/23199705

 

Neuromodulators for pain management in rheumatoid arthritis                     (abst – 2012)

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008921.pub2/abstract

 

Reefer tokin’ seniors in South Florida see pain go up in smoke                       (news – 2012)

http://articles.sun-sentinel.com/2012-07-23/news/fl-toking-oldsters-20120723_1_reefer-pain-seniors

 

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