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Anti-inflammatory properties of cannabichromene                        (abst – 1980)


Biological activity of cannabichromene, its homologs and isomers.                   (abst – 1981)


Analgesic and antiinflammatory activity of constituents of Cannabis sativa L. (full – 1988)


Antiinflammatory and antimicrobial compounds and compositions

United States Patent 4837228                  (full – 1989)


1′,1′-Dimethylheptyl-Δ-8-tetrahydrocannabinol-11-oic Acid: A Novel, Orally Effective Cannabinoid with Analgesic and Anti-inflammatory Properties                                                  (full – 1999)  marihuana&searchid=1&FIRSTINDEX=1840&resourcetype=HWCIT


Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat                                                               (full – 2002)


Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2 Cannabinoid Receptors          (full – 2003)



Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst – 2003)                              


New perspectives in the studies on endocannabinoid and cannabis: 2- arachidonoylglycerol as a possible novel mediator of inflammation                                                                                       (full – 2004)


Cannabinoids and neuroinflammation                     (full – 2004)


Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation.            (full – 2004)                         


A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis.                                                        (full – 2004)


The cannabinoid receptor agonist WIN 55212-2 inhibits neurogenic inflammations in airway tissues.       (full – 2005)                        



Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full – 2005)                          


Ajulemic acid (IP-751): Synthesis, proof of principle, toxicity studies, and clinical trials (full – 2005)                       


Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson’s disease.                                               (abst – 2005)


Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.         (abst – 2005)            


Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes                                                          (full – 2006)


Involvement of the Cannabinoid CB2 Receptor and Its Endogenous Ligand 2- Arachidonoylglycerol in Oxazolone-Induced Contact Dermatitis in Mice                                                                      (full – 2006)


The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells.                                                                    (abst – 2006)


Cannabinoid-Induced Immune Suppression and Modulation of Antigen-Presenting Cells (abst – 2006)                          


Anandamide, an endocannabinoid, protects neurons from inflammation after brain damage          (news – 2006)


Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain   (full – 2007)        


Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis

(full – 2007)     


Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression (Alzheimer’s)                                                    (full – 2007)


Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.                                                            (full – 2007)


Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro      (full – 2007)


Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation                                           (full – 2007)


Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis                                              (full – 2007)   binoid&searchid=1&FIRSTINDEX=240&resourcetype=HWCIT


The endocannabinoid system in targeting inflammatory neurodegenerative diseases (full – 2007) ry_neuro.pdf


Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain            (full – 2007)


Endocannabinoids, cannabinoid receptors and inflammatory stress: an interview with Dr. Pál Pacher       (interview – 2007)



Cannabinoids and neuroprotection in motor-related disorders.              (abst – 2007)


Cannabinoids for the treatment of inflammation.               (abst – 2007) tplus


A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain.                                       (abst – 2007)


Constituents Of Hashish And Marijuana May Help To Fight Inflammation And Allergies (news – 2007)                                


Pot Chemical May Curb Inflammation                 (news – 2007)


Endocannabinoids appear to play important role in regulating inflammation (news – 2007)  


Anti-inflammatory cannabinoids in diet               (full – 2008)



Cannabinoid receptors in acute and chronic complications of atherosclerosis (full – 2008)                        


Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats. (full -2008)                         


Inflammation and aging: can endocannabinoids help?               (full – 2008)


Cannabinoid CB2 receptors in human brain inflammation               (full – 2008)


Cannabinoid Modulation of Cutaneous A{delta} Nociceptors During Inflammation (full – 2008)                          


Cannabinoid modulation of cutaneous Adelta nociceptors during inflammation. (full – 2008)                           


Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders. (abst – 2008) view_of_its_therapeutic_potential_in_CNS_disorders_


Scientists are High on Idea that Cannabis Reduces Memory Impairment             (news – 2008)


Why Cannabis Stems Inflammation              (news – 2008)


Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects       (full – 2009)


Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis                                                                    (full – 2009)


Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells        (full – 2009)


Ajulemic acid, a synthetic cannabinoid, increases formation of the endogenous proresolving and anti-inflammatory eicosanoid, lipoxin A4                                                                           (full – 2009)  annabis&searchid=1&FIRSTINDEX=2400&resourcetype=HWCIT


Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease


(full – 2009)    


Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death                                                              (full – 2009)


Cannabinoids as novel anti-inflammatory drugs.               (full – 2009)


The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function                                                          (full – 2009)


Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation

(full – 2009)       


Endocannabinoid signalling as an anti-inflammatory therapeutic target in atherosclerosis: does it work?   (full – 2009)  4a971695b4fb


Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro- inflammatory cytokines during experimental periodontitis in rats.                                                        (abst – 2009)


Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis. (abst – 2009)                           


How Hemp Seed Oil Can Help Your Arthritis                 (news – 2009)


Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. (full – 2010)                         


Cannabinoids and Viral Infections                (full – 2010)




The endocannabinoid system as a target for the treatment of neurodegenerative disease (full – 2010)                         


The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis.                                                          (full – 2010)



Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation    (full – 2010)


Synthesis of Novel Cannabinoid Ligands and Their Use as Anti-Glioma and Anti- Inflammatory Agents            (full – 2010)


N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor                                                         (full – 2010)


Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion.                                                                  (abst – 2010)


WIN55212-2 ameliorates atherosclerosis associated with suppression of pro- inflammatory responses in ApoE-knockout mice.                                                                        (abst – 2010)


Beneficial effects of cannabinoids (CB) in a murine model of allergen-induced airway inflammation: Role of CB(1)/CB(2) receptors.                                                     (abst – 2010)


oids              CB






Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats.                                                        (abst – 2010)


Hemp Oil Benefits for Skin                 (news – 2010)


Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study                                                  (full – 2011)


Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement                                                                 (full – 2011)


Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full – 2011)


Gut feelings about the endocannabinoid system                (full – 2011)


Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis. (full – 2011)                          


Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents.                                                  (full – 2011)


Cannabinoid CB2 Receptors Contribute to Upregulation of β-endorphin in Inflamed Skin Tissues by Electroacupuncture                                      (full – 2011)


The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids.

(full – 2011)       


Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation.       (full – 2011)                              


Cannabinoids and Innate Immunity: Taking a Toll on Neuroinflammation (link to PDF– 2011)                                   


Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.                                           (abst – 2011)     


GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils. (abst – 2011) 2_receptor_mediated_responses_in_human_neutrophils_


Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation                                                         (abst – 2011)


Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis.                                            (abst – 2011)


Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and cell death                                                  (abst – 2011)

&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=160&sortspec=date&resourcet  ype=HWCIT


Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9) -tetrahydrocannabinol in BV-2 microglial cells                                   (abst – 2011)



Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. (abst – 2011) epatic_ischemia/reperfusion_injury_by_attenuating_inflammatory_signaling_and_response_oxidative/nitra  tive_stress_and_cell_death_


Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection.                                                           (abst – 2011)


A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells.          (abst – 2011) 940_inhibits_lipopolysaccharide_induced_cytokine_mRNA_expression_in_a_cannabinoid_receptor_indep  endent_mechanism_in_rat_cerebellar_granule_cells_


Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.                                                   (abst – 2011) annabinoid_enriched_Cannabis_extracts_on_TRP_channels_and_endocannabinoid_metabolic_enzymes_


Allergen Challenge Increases Anandamide in Bronchoalveolar Fluid of Patients With Allergic Asthma   (abst – 2011)                    


New metabolic pathway for controlling brain inflammation (news – 2011)  inflammation.aspx


Prolonged oral Cannabinoid Administration prevents Neuroinflammation, lowers beta- amyloid Levels and improves Cognitive Performance in Tg APP 2576 Mice.

(full – 2012)       


A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer’s Disease                                                                (full – 2012)


The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation (full – 2012)                          


Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain         (full – 2012)                                            


The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α                                                         (full – 2012)



Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?                                                        (full – 2012)


Update on the role of cannabinoid receptors after ischemic stroke.                     (full – 2012)


Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress.                                                            (full – 2012)


Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α.

(full – 2012)              


The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation (full – 2012)                               


Cannabinoid modulation of neuroinflammatory disorders.                    (full – 2012)


Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues                                                               (full – 2012)


Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice.   (abst – 2012)                      


Review article: Mast cell–glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide                                                            (abst – 2012)


Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a

`             murine model of acute lung injury: Role for the adenosine A(2A) receptor.   (abst – 2012)


Endocannabinoids limit excessive mast cell maturation and activation in human skin. (abst – 2012)                                  


The endocannabinoid system: a revolving plate in neuro-immune interaction in health and disease.          (abst – 2012)                     


Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis.                                                 (abst – 2012)


The Role of Cannabinoids In Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke.                                                                     (abst – 2012)


WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.                                                        (abst – 2012)


Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?                                              (abst – 2012)


Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.       (abst – 2012)                   


Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice                                                                (abst – 2012)  cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT


Differential migratory properties of monocytes isolated from human subjects naïve and non-naïve to Cannabis.                                                   (abst – 2012)


Cannabinoid receptor-2-selective agonists improve recovery in experimental autoimmune encephalomyelitis                                             (abst – 2012)

=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&resou  rcetype=HWCIT


Anti-Inflammatory Effect of the Endocannabinoid Anandamide in Experimental Periodontitis and Stress in the Rat.                                                                (abst – 2012)


Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions.                                                       (abst – 2012)


Palmitoylethanolamide is a new possible pharmacological treatment for the inflammation associated with trauma.                                                     (abst – 2012)


Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammation.                                                                 (abst – 2012)


Cannabinoids inhibit peptidoglycan-induced phosphorylation of NF-κB and cell growth in U87MG human malignant glioma cells.                                              (abst – 2012)


Differential Modulation by Delta(9)-Tetrahydrocannabinol (∆ (9)-THC) of CD40 Ligand (CD40L) Expression in Activated Mouse Splenic CD4(+) T cells.                                                       (abst – 2012)


Cannabidiol treatment ameliorates ischemia/reperfusion renal injury in rats. (abst – 2012)                             


A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury.                                                              (abst – 2012)


Signaling through cannabinoid receptor 2 suppresses murine dendritic cell migration by inhibiting matrix metalloproteinase 9 expression.                                         (abst – 2012)


A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis.          (abst – 2012)        


Activation of Cannabinoid Receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms. (abst – 2012)


N-acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids – From fishy endocannabinoids to potential leads                                                             (abst – 2012)


Anti-Inflammatory Effect of the Endocannabinoid Anandamide in Experimental Periodontitis and Stress in the Rat                                                                    (abst – 2012)


Palmitoylethanolamide is a new possible pharmacological treatment for the inflammation associated with trauma.  (abst – 2012)


CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation                                                        (abst – 2012)


β−Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB1 or CB2 receptors    (abst – 2012)


Update on the endocannabinoid-mediated regulation of gelatinase release in arterial wall physiology and atherosclerotic pathophysiology.                                         (abst – 2012)


Cannabidiol (CBD) enhances lipopolysaccharide (LPS)-induced pulmonary inflammation in C57BL/6 mice.                                          (abst – 2012)


The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects.                                                (abst – 2013)


The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis.                                                                       (abst – 2013)


Inhibition of endocannabinoid degradation in experimental endotoxemia reduces leukocyte adhesion and improves capillary perfusion in the gut.                                                                               (abst – 2013)


New Insights in Mast Cell Modulation by Palmitoylethanolamide.                      (abst – 2013)

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