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AM-404– cannabinoid transport inhibitor

AM-404– cannabinoid transport inhibitor

 

Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172.                                 (full – 2004)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC423268/

 

Easing anxiety with anandamide        (news – 2004)

http://www.rsc.org/chemistryworld/Issues/2004/July/anandamide.asp

 

Synergistic Interactions between Cannabinoids and Environmental Stress in the Activation of the Central Amygdala                             (full – 2005)  http://www.nature.com/npp/journal/v30/n3/full/1300535a.html

 

Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear (full – 2005)                            http://www.nature.com/npp/journal/v30/n3/full/1300655a.html

 

Anxiolytic-like properties of the anandamide transport inhibitor AM404.       (full – 2006)

http://www.nature.com/npp/journal/v31/n12/full/1301061a.html

 

Δ9-Tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors                                   (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189998/?tool=pmcentrez

 

Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus.                                     (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21767554

 

The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats

(abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21557729/abstract/The_anandamide_transport_inh  ibitor_AM404_reduces_the_rewarding_effects_of_nicotine_and_nicotine_induced_dopamine_elevations_i n_the_nucleus_accumbens_shell_in_rats_

 

The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats.

(abst – 2011)        http://www.ncbi.nlm.nih.gov/pubmed/21557729

 

Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor.    (abst – 2012)         http://www.ncbi.nlm.nih.gov/pubmed/22248639

 

Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration.                         (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22133635

 

Inhibition of fatty acid amide hydrolase by URB597 attenuates the anxiolytic-like effect of acetaminophen in the mouse elevated plus-maze test.              (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22750843

 

 

Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats. (abst – 2012)                          http://www.ncbi.nlm.nih.gov/pubmed/22959964

 

Involvement of the Endocannabinoid System in Ethanol-Induced Corticostriatal Synaptic Depression.                        (abst – 2012)    http://www.ncbi.nlm.nih.gov/pubmed/22971846

 

Diuretic effects of cannabinoids.  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23019138

 

 

 

 

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