AM-1241– synthetic, CB 2 agonist

 

Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS                        (full – 2003)  http://www.pnas.org/content/100/18/10529.full

 

Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2 Cannabinoid Receptors                          (full – 2003)  http://journals.lww.com/anesthesiology/Fulltext/2003/10000/Inhibition_of_Inflammatory_Hyperalgesia_by

.31.aspx

 

New Compound That Acts On Peripheral Receptors May Be Promising Treatment For Some Nerve Pain                            (news – 2003)  http://www.sciencedaily.com/releases/2003/08/030812073750.htm

 

CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids                     (full – 2005)          http://www.pnas.org/content/102/8/3093.full

 

Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain.                                      (abst – 2005)           http://www.ncbi.nlm.nih.gov/pubmed/16316653

 

In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor?                                      (full – 2006)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2013801/?tool=pubmed

 

AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis.                                      (abst – 2006)  http://www.ncbi.nlm.nih.gov/pubmed/16781706

 

The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset                                  (full – 2007)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819701/?tool=pmcentrez

 

Peripheral Cannabinoids Attenuate Carcinoma Induced Nociception in Mice (full – 2008)                               http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771220/

 

Selective Activation of Cannabinoid CB2 Receptors Suppresses Neuropathic Nociception Induced by Treatment with the Chemotherapeutic Agent Paclitaxel in Rats (full – 2008)  http://jpet.aspetjournals.org/content/327/2/584.full#content-block

 

The endocannabinoid system in amyotrophic lateral sclerosis.      (abst – 2008)

http://www.ncbi.nlm.nih.gov/pubmed/18781981

 

Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis. (full – 2009)                               http://onlinelibrary.wiley.com/doi/10.1002/ibd.20960/full

 

Spinal and peripheral analgesic effects of the CB cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain.                                    (full – 2010)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931557/?tool=pubmed

 

A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. (abst – 2010)                              http://www.ncbi.nlm.nih.gov/pubmed/20176037

 

Cannabinoids attenuate cancer pain and proliferation in a mouse model.

(full – 2011)         http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099480/?tool=pubmed

 

Self-medication of a cannabinoid CB(2) agonist in an animal model of neuropathic pain. (abst – 2011)  http://www.unboundmedicine.com/medline/ebm/record/21550725/abstract/Self_medication_of_a_cannabin

 

 

 

Regulation of hematopoietic stem cell trafficking and mobilization by the endocannabinoid system.  (abst – 2011)                                     http://www.ncbi.nlm.nih.gov/pubmed/22074629

 

Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. (abst – 2011)  http://www.ncbi.nlm.nih.gov/pubmed/21063029

 

Antinociceptive effects induced through the stimulation of spinal cannabinoid type 2 receptors in chronically inflamed mice                             (abst – 2011)

 

http://www.unboundmedicine.com/medline/ebm/record/21771590/abstract/Antinociceptive_effects_induce   d_through_the_stimulation_of_spinal_cannabinoid_type_2_receptors_in_chronically_inflamed_mice_

 

Effects of a Selective Cannabinoid CB2 Agonist and Antagonist on Intravenous Nicotine Self Administration and Reinstatement of Nicotine Seeking.             (full – 2012)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266883/?tool=pubmed

 

Therapeutic modulation of cannabinoid lipid signaling: Metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist.                                 (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22749867

 

Prevention of Fibrosis Progression in CCl4-Treated Rats: Role of the Hepatic Endocannabinoid and Apelin Systems                                            (abst – 2012)  http://jpet.aspetjournals.org/content/340/3/629.abstract?sid=ae58f15a-06bb-4a81-b850-61bb89fd59f5

 

Diuretic effects of cannabinoids.  (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/23019138

 

Cannabinoid Receptors as Therapeutic Targets for Dialysis-Induced Peritoneal Fibrosis. (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23296044

 

 

 

 

Share a link for