Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer’s disease.   (abst – 1997)


Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. (abst – 2002)                 


US Patent 6630507 – Cannabinoids as antioxidants and neuroprotectants    (full – 2003)


Cannabinoid CB2 Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer’s Disease Brains (full – 2003)  cannabinoid&searchid=1&FIRSTINDEX=80&resourcetype=HWCIT


Safety and efficacy of Dronabinol in the treatment of agitation in patients with Alzheimer’s disease with anorexia                             (abst – 2003)


Open-label study of  Dronabinol in the treatment of refractory agitation in Alzheimer’s disease : a pilot study                                  (abst – 2003)


Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on β-amyloid-induced toxicity in PC12 cells                             (full – 2004)


Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. (full – 2005)                          


Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (full – 2005)                       


Prevention of Alzheimer’s Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation                               (full – 2005)


Avoidance of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and PI3K- dependent mechanisms: role of NF-kappaB and p53.                                                          (abst – 2005)


Phosphorylated amyloid-beta: the toxic intermediate in alzheimer’s disease neurodegeneration.                                       (abst – 2005)


Cannabinoid control of motor function at the basal ganglia.       (abst – 2005)


Marijuana Ingredient May Stall Decline From Alzheimer’s        (news – 2005)


Research shows preventive effects of cannabinoids on Alzheimer’s disease (news – 2005)                      


Marijuana Slows Alzheimer’s Decline             (news – 2005)


Marijuana May Block Alzheimer’s            (news – 2005)


Marijuana Ingredient May Help Alzheimer’s          (news – 2005)


Cannabinoids reduce the progression of Alzheimer’s disease in animals        (news – 2005)


Pass the Doobie, pops         (news – 2005)


The Cannabinoid CB2 Receptor as a Target for Inflammation-Dependent Neurodegeneration                                         (full – 2006)


A Molecular Link between the Active Component of Marijuana and Alzheimer’s Disease Pathology                      (full – 2006)


Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia

(full – 2006)


Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels.                                    (abst – 2006)


Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF- kappaB involvement.   (abst – 2006)                               


The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells. (abst – 2006)                         


CB1 receptor selective activation inhibits beta-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylation in co-cultured neurons. (abst – 2006)           


Marijuana Compound Efficient Against Alzheimer’s Disease (news – 2006)


THC inhibits primary marker of Alzheimer’s disease         (news – 2006)


Marijuana’s Active Ingredient Shown to Inhibit Primary Marker of Alzheimer’s Disease (news – 2006)                       


Marijuana’s Active Ingredient May Slow Progression Of Alzheimer’s Disease (news – 2006)                     


Marijuana may help stave off Alzheimer’s       (news – 2006)


Marijuana May Slow Alzheimer’s         (news – 2006)


Pot-Like Compound May Slow Alzheimer’s        (news – 2006)


Latest Buzz: Marijuana May Slow Progression Of Alzheimer’s Disease       (news – 2006)


Alzheimer’s disease; taking the edge off with cannabinoids?        (full – 2007)


Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression                         (full – 2007)


Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.                                        (full – 2007)


Anti-inflammatory property of the cannabinoid agonist WIN-55212-2 in a rodent model of chronic brain inflammation                                    (full – 2007)


The endocannabinoid system in targeting inflammatory neurodegenerative diseases (full – 2007)  ry_neuro.pdf


Cannabinoid CB2 receptors in human brain inflammation       (full – 2008)


Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats (full – 2008)                 


Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease (full – 2008)                 


Inflammation and aging: can endocannabinoids help?       (full – 2008)


Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids.                                                      (full – 2008)


Role of CB2 receptors in neuroprotective effects of cannabinoids.      (abst – 2008)


The role of the endocannabinoid system in Alzheimer’s disease: facts and hypotheses. (abst – 2008)                       


Scientists are High on Idea that Cannabis Reduces Memory Impairment      (news – 2008)


Israeli Research Shows Cannabidiol May Slow Alzheimer’s Disease       (news – 2008)


Marijuana may be good for the aging brain        (news – 2008)


Alzheimer’s sufferers may benefit from cannabis compound       (news – 2008)


Marijuana reduces memory impairment        (news – 2008)


Cannabis ‘could stop dementia in its tracks’        (news – 2008)


LSUHSC research reports new method to protect brain cells from diseases like Alzheimer’s  (news – 2008)             


Could Marijuana Substance Help Prevent Or Delay Memory Impairment In The Aging Brain?          (news – 2008)


Attacking Alzheimer’s with Red Wine and Marijuana          (news – 2008)


Can cannabis offer hope for Alzheimer’s?           (news – 2008)


Cannabis-derived medicines may help Alzheimer’s        (news – 2008)


Pot joins the fight against Alzheimer’s, memory loss         (news – 2008) alzheim-2008-11-19


Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects                              (full – 2009)


Cannabidiol: a promising drug for neurodegenerative disorders?       (full – 2009)


The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages.                                         (abst – 2009)   nel.Pubmed_RVDocSum&ordinalpos=18


Endocannabinoids prevent lysosomal membrane destabilisation evoked by treatment with β-amyloid in cultured rat cortical neurons                             (abst – 2009)  study.html#post14325992


Medical Marijuana and Alzheimer’s Disease        (news – 2009)


Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality.                                  (full – 2010)


Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain (full – 2010)                   


Cannabinoids and Dementia: A Review of Clinical and Preclinical Data (link to PDF – 2010)                    


The development of cannabinoid CBII receptor agonists for the treatment of central neuropathies.   (abst – 2010)  oid_CBII_receptor_agonists_for_the_treatment_of_central_neuropathies_


Endocannabinoids Prevent β-Amyloid-mediated Lysosomal Destabilization in Cultured Neurons    (abst – 2010) 


The endocannabinoid system in gp120-mediated insults and HIV-associated dementia. (abst – 2010)                  


The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration.    (abst – 2010)                    


Marijuana could prevent Alzheimer’s       (news – 2010)


Newly discovered mechanism controls levels and efficacy of a marijuana-like substance in the brain (news – 2010)


Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers’ disease                           (full – 2011)


Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement                               (full – 2011)


Gadolinium-HU-308-incorporated micelles.         (full – 2011)


US Patent Application 20110257256 – CANNABINOIDS FOR USE IN TREATING OR PREVENTING COGNITIVE IMPAIRMENT AND DEMENTIA                               (full – 2011)


Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011)                


Anandamide and its congeners inhibit human plasma butyrylcholinesterase. Possible new roles for these endocannabinoids?                                 (abst – 2011)


Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.                                      (abst – 2011)   


An amyloid β(42)-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer’s disease                                                    (abst – 2011)          d

ependent_deficit_in_anandamide_mobilization_is_associated_with_cognitive_dysfunction_in_Alzheimer%  27s_disease_


Molecular reorganization of endocannabinoid signalling in Alzheimer’s disease. (abst – 2011) ndocannabinoid_signalling_in_Alzheimer%27s_disease_


Palmitoylethanolamide counteracts reactive astrogliosis induced by beta-amyloid peptide. (abst – 2011)                    


The role of phytochemicals in the treatment and prevention of dementia.       (abst – 2011)   n_the_treatment_and_prevention_of_dementia_


Early onset of aging-like changes is restricted to cognitive abilities and skin structure in Cnr1(-/-) mice.                              (abst – 2011) 



Intact cannabinoid CB1 receptors in the Alzheimer’s disease cortex.      (abst – 2011)


The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia.                                        (abst – 2011)


Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults. (abst – 2011)  ylglycerol_protects_neurons_against_%CE%B2_amyloid_insults_


New metabolic pathway for controlling brain inflammation          (news – 2011)  inflammation.aspx


Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?                                         (full – 2012)


Prolonged oral Cannabinoid Administration prevents Neuroinflammation, lowers beta- amyloid Levels and improves Cognitive Performance in Tg APP 2576 Mice.

(full – 2012)


A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer’s Disease                                     (full – 2012)


Monoacylglycerol lipase is a new therapeutic target for Alzheimer’s disease (full – 2012)                   


Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α

(full – 2012)


The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation (full – 2012)                   


Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?                                         (full – 2012)


Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors? (full – 2012)                   


Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α.

(full – 2012)


The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-beta and in the cortex of aged rats.                                          (full – 2012)


Review article: The endocannabinoid system in normal and pathological brain ageing (abst – 2012)                      


Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. (abst – 2012)                      


Protective effect of cannabinoid CB1 receptor activation against altered intrinsic repetitive firing properties induced by Aβ neurotoxicity.                                 (abst – 2012)


Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro.                                       (abst – 2012)


[(125)I]SD-7015 reveals fine modalities of CB(1) cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer’s disease.                                    (abst – 2012)


CB1 Agonist ACEA Protects Neurons and Reduces the Cognitive Impairment of AβPP/PS1 Mice.                                  (abst – 2012)


CB1 cannabinoid receptor activation rescues amyloid β-induced alterations in behaviour and intrinsic electrophysiological properties of rat hippocampal CA1 pyramidal neurones. (abst – 2012)                    


The therapeutic potential of the endocannabinoid system for Alzheimer’s disease. (abst – 2012)                    


WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.                            (abst – 2012)


CB(2) receptor and amyloid pathology in frontal cortex of Alzheimer’s disease patients. (abst – 2012)                    


In vivo type 1 cannabinoid receptor availability in Alzheimer’s disease        (abst – 2012)

&hits=25&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=130&sortspec=date&  resourcetype=HWCIT


Essential fatty acids and lipid mediators. Endocannabinoids         (abst – 2012)


β−Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB1 or CB2 receptors        (abst – 2012)


How Weed Can Protect Us From Cancer and Alzheimer’s       (book excerpt – 2012)


Marijuana Compound Found Superior To Drugs For Alzheimer’s (news – 2012) –   print.html


How Cannabinoids May Slow Brain Aging         (news – 2012)


Cannabinoid Receptor Stimulator Reverses Symptoms of Alzheimer’s Disease in Animal Model                 (news – 2012)


Researchers investigating potential drug for treatement of Alzheimer’s disease (news – 2012)


Research identifies new therapeutic target for Alzheimer’s disease      (news – 2012)


Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. (abst – 2013)                    


CB(2) receptor and amyloid pathology in frontal cortex of Alzheimer’s disease patients. (abst – 2013)                    


Multitarget Cannabinoids as Novel Strategy for Alzheimer Disease.        (abst – 2013)



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