endocannabinoid, CB 1 & 2 agonist


Phytocannabinoids        (news – undated)



2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor (full – 2001)                              http://www.ncbi.nlm.nih.gov/pmc/articles/PMC31108/


Comparison of the enzymatic stability and intraocular pressure effects of 2- arachidonylglycerol and noladin ether, a novel putative endocannabinoid.                                            (full – 2002)  http://www.iovs.org/content/43/10/3216.full


Endocannabinoid Degradation, Endotoxic Shock and Inflammation (link to PDF – 2002)                               http://www.eurekaselect.com/91915/article


Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. (abst – 2002)                               http://www.ncbi.nlm.nih.gov/pubmed/12384227


Endocannabinoids and related fatty acid derivatives in pain modulation.     (abst – 2002)



Synthesis, in vitro evaluation, and intraocular pressure effects of water-soluble prodrugs of endocannabinoid noladin ether.            (abst – 2003)  http://www.ncbi.nlm.nih.gov/pubmed/14584958


The endocannabinoid noladin ether acts as a full agonist at human CB2 cannabinoid receptors.  (full – 2005)       http://jpet.aspetjournals.org/content/314/2/868.long


Effects of the endocannabinoid noladin ether on body weight, food consumption, locomotor activity, and cognitive index in mice.                          (abst – 2005)  http://www.ncbi.nlm.nih.gov/pubmed/15763177


Noladin ether acts on trabecular meshwork cannabinoid (CB1) receptors to enhance aqueous humor outflow facility.                              (full – 2006)      http://www.iovs.org/content/47/5/1999.long


2-Arachidonylglyceryl ether and abnormal cannabidiol-induced vascular smooth muscle relaxation in rabbit pulmonary arteries via receptor-pertussis toxin sensitive G proteins- ERK1/2 signaling.     (abst – 2007)                          http://www.ncbi.nlm.nih.gov/pubmed/17292352


Alterations in the hippocampal endocannabinoid system in diet-induced obese mice. (full – 2010)                            http://www.jneurosci.org/content/30/18/6273.long


Endogenous cannabinoids in liver disease: Many darts for a single target       (abst – 2010)



Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol.


(full – 2011)          http://onlinelibrary.wiley.com/doi/10.1002/biof.131/full


Anti-proliferative Effect of a Putative Endocannabinoid, 2-Arachidonylglyceryl Ether in Prostate Carcinoma Cells                     (full – 2011)  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039283/?tool=pmcentrez


Noladin ether, a putative endocannabinoid, enhances motivation to eat after acute systemic administration in rats.   (abst – 2012)                                            http://www.ncbi.nlm.nih.gov/pubmed/22309979


Stimulation of acumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats.      (abst – 2012)  http://www.ncbi.nlm.nih.gov/pubmed/22728691


Stimulatory and Inhibitory Roles of Brain 2-Arachidonoylglycerol in Bombesin-Induced Central Activation of Adrenomedullary Outflow in Rats.                       (abst – 2013)  http://www.ncbi.nlm.nih.gov/pubmed/23386378




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